<?xml version="1.0" encoding="US-ASCII"?>
<!--XBRL Document Created with Wdesk from Workiva-->
<!-- -->
<link:linkbase xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/Acquisitions" xlink:href="livn-20170930.xsd#Acquisitions" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/AcquisitionsContingentConsiderationDetails" xlink:href="livn-20170930.xsd#AcquisitionsContingentConsiderationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/AcquisitionsContingentConsiderationReconciliationDetails" xlink:href="livn-20170930.xsd#AcquisitionsContingentConsiderationReconciliationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/AcquisitionsNarrativeDetails" xlink:href="livn-20170930.xsd#AcquisitionsNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/AcquisitionsPreliminaryPurchasePriceAllocationDetails" xlink:href="livn-20170930.xsd#AcquisitionsPreliminaryPurchasePriceAllocationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/AcquisitionsPurchasePriceCompositionDetails" xlink:href="livn-20170930.xsd#AcquisitionsPurchasePriceCompositionDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/AcquisitionsTables" xlink:href="livn-20170930.xsd#AcquisitionsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/CommitmentsAndContingencies" xlink:href="livn-20170930.xsd#CommitmentsAndContingencies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/CommitmentsAndContingenciesNarrativeDetails" xlink:href="livn-20170930.xsd#CommitmentsAndContingenciesNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/CondensedConsolidatedBalanceSheets" xlink:href="livn-20170930.xsd#CondensedConsolidatedBalanceSheets" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/CondensedConsolidatedBalanceSheetsParenthetical" xlink:href="livn-20170930.xsd#CondensedConsolidatedBalanceSheetsParenthetical" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/CondensedConsolidatedStatementsOfCashFlowsUnaudited" xlink:href="livn-20170930.xsd#CondensedConsolidatedStatementsOfCashFlowsUnaudited" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/CondensedConsolidatedStatementsOfComprehensiveIncomeLossUnaudited" xlink:href="livn-20170930.xsd#CondensedConsolidatedStatementsOfComprehensiveIncomeLossUnaudited" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/CondensedConsolidatedStatementsOfIncomeLossUnaudited" xlink:href="livn-20170930.xsd#CondensedConsolidatedStatementsOfIncomeLossUnaudited" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagement" xlink:href="livn-20170930.xsd#DerivativesAndRiskManagement" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementAmountOfGainLossRecognizedInOciAndIncomeStatementDetails" xlink:href="livn-20170930.xsd#DerivativesAndRiskManagementAmountOfGainLossRecognizedInOciAndIncomeStatementDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementDerivativeNotionalAmountsDetails" xlink:href="livn-20170930.xsd#DerivativesAndRiskManagementDerivativeNotionalAmountsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementFairValueOfDerivativeInstrumentsDetails" xlink:href="livn-20170930.xsd#DerivativesAndRiskManagementFairValueOfDerivativeInstrumentsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementNarrativeDetails" xlink:href="livn-20170930.xsd#DerivativesAndRiskManagementNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementTables" xlink:href="livn-20170930.xsd#DerivativesAndRiskManagementTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/DocumentAndEntityInformation" xlink:href="livn-20170930.xsd#DocumentAndEntityInformation" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/FairValueMeasurements" xlink:href="livn-20170930.xsd#FairValueMeasurements" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/FairValueMeasurementsAssetsAndLiabilitiesThatAreMeasuredAtFairValueOnRecurringBasisDetails" xlink:href="livn-20170930.xsd#FairValueMeasurementsAssetsAndLiabilitiesThatAreMeasuredAtFairValueOnRecurringBasisDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/FairValueMeasurementsTables" xlink:href="livn-20170930.xsd#FairValueMeasurementsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/FinancingArrangements" xlink:href="livn-20170930.xsd#FinancingArrangements" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/FinancingArrangementsLongTermDebtOutstandingRevolvingCreditAndEuropeanInvestmentBankFinancingAgreementDetails" xlink:href="livn-20170930.xsd#FinancingArrangementsLongTermDebtOutstandingRevolvingCreditAndEuropeanInvestmentBankFinancingAgreementDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/FinancingArrangementsTables" xlink:href="livn-20170930.xsd#FinancingArrangementsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformation" xlink:href="livn-20170930.xsd#GeographicAndSegmentInformation" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformationChangesInCarryingAmountOfGoodwillDetails" xlink:href="livn-20170930.xsd#GeographicAndSegmentInformationChangesInCarryingAmountOfGoodwillDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformationGeographicAreasDetails" xlink:href="livn-20170930.xsd#GeographicAndSegmentInformationGeographicAreasDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformationSegmentInfoDetails" xlink:href="livn-20170930.xsd#GeographicAndSegmentInformationSegmentInfoDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformationTables" xlink:href="livn-20170930.xsd#GeographicAndSegmentInformationTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/IncomeTaxes" xlink:href="livn-20170930.xsd#IncomeTaxes" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/IncomeTaxesNarrativeDetails" xlink:href="livn-20170930.xsd#IncomeTaxesNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/Investments" xlink:href="livn-20170930.xsd#Investments" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/InvestmentsCostMethodInvestmentsDetails" xlink:href="livn-20170930.xsd#InvestmentsCostMethodInvestmentsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/InvestmentsEquityMethodInvestmentsDetails" xlink:href="livn-20170930.xsd#InvestmentsEquityMethodInvestmentsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/InvestmentsTables" xlink:href="livn-20170930.xsd#InvestmentsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/NetIncomeLossPerShare" xlink:href="livn-20170930.xsd#NetIncomeLossPerShare" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/NetIncomeLossPerShareNarrativeOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareDetails" xlink:href="livn-20170930.xsd#NetIncomeLossPerShareNarrativeOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/NetIncomeLossPerShareScheduleOfEarningsPerShareBasicAndDilutedDetails" xlink:href="livn-20170930.xsd#NetIncomeLossPerShareScheduleOfEarningsPerShareBasicAndDilutedDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/NetIncomeLossPerShareTables" xlink:href="livn-20170930.xsd#NetIncomeLossPerShareTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/NewAccountingPronouncements" xlink:href="livn-20170930.xsd#NewAccountingPronouncements" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/NewAccountingPronouncementsDetails" xlink:href="livn-20170930.xsd#NewAccountingPronouncementsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/ProductRemediationLiability" xlink:href="livn-20170930.xsd#ProductRemediationLiability" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/ProductRemediationLiabilityDetails" xlink:href="livn-20170930.xsd#ProductRemediationLiabilityDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/ProductRemediationLiabilityTables" xlink:href="livn-20170930.xsd#ProductRemediationLiabilityTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/Restructuring" xlink:href="livn-20170930.xsd#Restructuring" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/RestructuringAccrualDetailDetails" xlink:href="livn-20170930.xsd#RestructuringAccrualDetailDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/RestructuringNarrativeDetails" xlink:href="livn-20170930.xsd#RestructuringNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/RestructuringRestructuringExpenseBySegmentDetails" xlink:href="livn-20170930.xsd#RestructuringRestructuringExpenseBySegmentDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/RestructuringTables" xlink:href="livn-20170930.xsd#RestructuringTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/StockBasedIncentivePlanCompensationExpenseDetails" xlink:href="livn-20170930.xsd#StockBasedIncentivePlanCompensationExpenseDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/StockBasedIncentivePlanExecutedAgreementsDetails" xlink:href="livn-20170930.xsd#StockBasedIncentivePlanExecutedAgreementsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/StockBasedIncentivePlanTables" xlink:href="livn-20170930.xsd#StockBasedIncentivePlanTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/StockBasedIncentivePlans" xlink:href="livn-20170930.xsd#StockBasedIncentivePlans" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/StockholdersEquity" xlink:href="livn-20170930.xsd#StockholdersEquity" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/StockholdersEquityComprehensiveIncomeDetails" xlink:href="livn-20170930.xsd#StockholdersEquityComprehensiveIncomeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/StockholdersEquityTables" xlink:href="livn-20170930.xsd#StockholdersEquityTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformation" xlink:href="livn-20170930.xsd#SupplementalFinancialInformation" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationSummaryOfAccountsReceivableDetails" xlink:href="livn-20170930.xsd#SupplementalFinancialInformationSummaryOfAccountsReceivableDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationSummaryOfAccruedLiabilitiesDetails" xlink:href="livn-20170930.xsd#SupplementalFinancialInformationSummaryOfAccruedLiabilitiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationSummaryOfInventoryDetails" xlink:href="livn-20170930.xsd#SupplementalFinancialInformationSummaryOfInventoryDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationSummaryOfOtherLongTermAssetsDetails" xlink:href="livn-20170930.xsd#SupplementalFinancialInformationSummaryOfOtherLongTermAssetsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationSummaryOfOtherLongTermLiabilitiesDetails" xlink:href="livn-20170930.xsd#SupplementalFinancialInformationSummaryOfOtherLongTermLiabilitiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationSummaryOfPrepaidExpensesAndOtherAssetsDetails" xlink:href="livn-20170930.xsd#SupplementalFinancialInformationSummaryOfPrepaidExpensesAndOtherAssetsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationTables" xlink:href="livn-20170930.xsd#SupplementalFinancialInformationTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/UnauditedCondensedConsolidatedFinancialStatements" xlink:href="livn-20170930.xsd#UnauditedCondensedConsolidatedFinancialStatements" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/UnauditedCondensedConsolidatedFinancialStatementsNarrativeDetails" xlink:href="livn-20170930.xsd#UnauditedCondensedConsolidatedFinancialStatementsNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/UnauditedCondensedConsolidatedFinancialStatementsPolicies" xlink:href="livn-20170930.xsd#UnauditedCondensedConsolidatedFinancialStatementsPolicies" xlink:type="simple" />
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/all" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#all" xlink:type="simple" />
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-default" xlink:type="simple" />
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-domain" xlink:type="simple" />
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/domain-member" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#domain-member" xlink:type="simple" />
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#hypercube-dimension" xlink:type="simple" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/Acquisitions" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/AcquisitionsContingentConsiderationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionContingentConsiderationLineItems" xlink:label="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_04409D5DE4C5885FEA9FDE6FFF9F2543" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_60F8E6C9ED5251856139DE6FFF9FAE1E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_04409D5DE4C5885FEA9FDE6FFF9F2543" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_60F8E6C9ED5251856139DE6FFF9FAE1E" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_B0C67EB7458A4DB9C69EDE6FFF9F4639" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_60F8E6C9ED5251856139DE6FFF9FAE1E" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_B0C67EB7458A4DB9C69EDE6FFF9F4639" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_7909DDB8E755C356ABDCDE6FFF9F4D31_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_B0C67EB7458A4DB9C69EDE6FFF9F4639" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_7909DDB8E755C356ABDCDE6FFF9F4D31_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_7909DDB8E755C356ABDCDE6FFF9F4D31" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_B0C67EB7458A4DB9C69EDE6FFF9F4639" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_7909DDB8E755C356ABDCDE6FFF9F4D31" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_CaissonInterventionalLLCMember" xlink:label="loc_livn_CaissonInterventionalLLCMember_D5DCBD579668B1E9A252DE6FFF9F6241" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_7909DDB8E755C356ABDCDE6FFF9F4D31" xlink:to="loc_livn_CaissonInterventionalLLCMember_D5DCBD579668B1E9A252DE6FFF9F6241" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ValuationTechniqueAxis" xlink:label="loc_us-gaap_ValuationTechniqueAxis_D105C224F37BDEF6380EDE6FFF9FB071" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_60F8E6C9ED5251856139DE6FFF9FAE1E" xlink:to="loc_us-gaap_ValuationTechniqueAxis_D105C224F37BDEF6380EDE6FFF9FB071" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ValuationTechniqueDomain" xlink:label="loc_us-gaap_ValuationTechniqueDomain_1331587D40FD07C43F69DE6FFF9FA417_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ValuationTechniqueAxis_D105C224F37BDEF6380EDE6FFF9FB071" xlink:to="loc_us-gaap_ValuationTechniqueDomain_1331587D40FD07C43F69DE6FFF9FA417_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ValuationTechniqueDomain" xlink:label="loc_us-gaap_ValuationTechniqueDomain_1331587D40FD07C43F69DE6FFF9FA417" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ValuationTechniqueAxis_D105C224F37BDEF6380EDE6FFF9FB071" xlink:to="loc_us-gaap_ValuationTechniqueDomain_1331587D40FD07C43F69DE6FFF9FA417" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_DiscountedCashFlowMember" xlink:label="loc_livn_DiscountedCashFlowMember_C442113AC0ACDBB5A68DDE6FFF9F33F6" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ValuationTechniqueDomain_1331587D40FD07C43F69DE6FFF9FA417" xlink:to="loc_livn_DiscountedCashFlowMember_C442113AC0ACDBB5A68DDE6FFF9F33F6" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_MonteCarloSimulationMember" xlink:label="loc_livn_MonteCarloSimulationMember_A55C14F03CA5A4A6CDE9DE6FFF9F6B4E" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ValuationTechniqueDomain_1331587D40FD07C43F69DE6FFF9FA417" xlink:to="loc_livn_MonteCarloSimulationMember_A55C14F03CA5A4A6CDE9DE6FFF9F6B4E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RangeAxis" xlink:label="loc_us-gaap_RangeAxis_75F8178AE1E698528A70DE6FFF9F9081" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_60F8E6C9ED5251856139DE6FFF9FAE1E" xlink:to="loc_us-gaap_RangeAxis_75F8178AE1E698528A70DE6FFF9F9081" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_77DEE308D3DAFB643146DE6FFF9F1F5E_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RangeAxis_75F8178AE1E698528A70DE6FFF9F9081" xlink:to="loc_us-gaap_RangeMember_77DEE308D3DAFB643146DE6FFF9F1F5E_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_77DEE308D3DAFB643146DE6FFF9F1F5E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RangeAxis_75F8178AE1E698528A70DE6FFF9F9081" xlink:to="loc_us-gaap_RangeMember_77DEE308D3DAFB643146DE6FFF9F1F5E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MinimumMember" xlink:label="loc_us-gaap_MinimumMember_5ECC80188EB3C090B59ADE6FFF9F7949" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RangeMember_77DEE308D3DAFB643146DE6FFF9F1F5E" xlink:to="loc_us-gaap_MinimumMember_5ECC80188EB3C090B59ADE6FFF9F7949" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MaximumMember" xlink:label="loc_us-gaap_MaximumMember_1B545B5308280D7E23D9DE6FFF9FC8CF" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RangeMember_77DEE308D3DAFB643146DE6FFF9F1F5E" xlink:to="loc_us-gaap_MaximumMember_1B545B5308280D7E23D9DE6FFF9FC8CF" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_BusinessCombinationContingentConsiderationRegulatoryMilestoneBasedPayments" xlink:label="loc_livn_BusinessCombinationContingentConsiderationRegulatoryMilestoneBasedPayments_C90370CF1D09FD22763FDE6FFFA0FABB" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_04409D5DE4C5885FEA9FDE6FFF9F2543" xlink:to="loc_livn_BusinessCombinationContingentConsiderationRegulatoryMilestoneBasedPayments_C90370CF1D09FD22763FDE6FFFA0FABB" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_BusinessCombinationContingentConsiderationSalesBasedEarnout" xlink:label="loc_livn_BusinessCombinationContingentConsiderationSalesBasedEarnout_3A56C52FE76E2B6F5A1EDE6FFFA09331" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_04409D5DE4C5885FEA9FDE6FFF9F2543" xlink:to="loc_livn_BusinessCombinationContingentConsiderationSalesBasedEarnout_3A56C52FE76E2B6F5A1EDE6FFFA09331" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_DCFDEBB47B38609F0E75DE6FFFA02A78" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_04409D5DE4C5885FEA9FDE6FFF9F2543" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_DCFDEBB47B38609F0E75DE6FFFA02A78" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueInputsDiscountRate" xlink:label="loc_us-gaap_FairValueInputsDiscountRate_FDD8FE793A2740A8AAC2DE6FFFA0579F" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_04409D5DE4C5885FEA9FDE6FFF9F2543" xlink:to="loc_us-gaap_FairValueInputsDiscountRate_FDD8FE793A2740A8AAC2DE6FFFA0579F" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_ProbabilityofPayment" xlink:label="loc_livn_ProbabilityofPayment_4975CBCEB4BAD7A13880DE6FFFA03F97" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_04409D5DE4C5885FEA9FDE6FFF9F2543" xlink:to="loc_livn_ProbabilityofPayment_4975CBCEB4BAD7A13880DE6FFFA03F97" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueAssumptionsExpectedVolatilityRate" xlink:label="loc_us-gaap_FairValueAssumptionsExpectedVolatilityRate_97DB48D611A75C0934EFDE86E5CE418C" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_04409D5DE4C5885FEA9FDE6FFF9F2543" xlink:to="loc_us-gaap_FairValueAssumptionsExpectedVolatilityRate_97DB48D611A75C0934EFDE86E5CE418C" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/AcquisitionsContingentConsiderationReconciliationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_58D6221673F492E805056DA43E540BEC" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_EECC063294161D5C2D336DA43E53B9DE" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_58D6221673F492E805056DA43E540BEC" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_EECC063294161D5C2D336DA43E53B9DE" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_E924853B08A523E95B096DA43E539C0B" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_EECC063294161D5C2D336DA43E53B9DE" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_E924853B08A523E95B096DA43E539C0B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_A26678D065D9280C5E496DA43E53B618_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_E924853B08A523E95B096DA43E539C0B" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_A26678D065D9280C5E496DA43E53B618_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_A26678D065D9280C5E496DA43E53B618" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_E924853B08A523E95B096DA43E539C0B" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_A26678D065D9280C5E496DA43E53B618" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueInputsLevel3Member" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_6CF70560B7FEDAACEBC46DA43E530237" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_A26678D065D9280C5E496DA43E53B618" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_6CF70560B7FEDAACEBC46DA43E530237" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_E148A64EC8DBB73404046DA43E539758" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_EECC063294161D5C2D336DA43E53B9DE" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_E148A64EC8DBB73404046DA43E539758" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_F6BD35E258B5D08C4D0E6DA43E535C81_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_E148A64EC8DBB73404046DA43E539758" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_F6BD35E258B5D08C4D0E6DA43E535C81_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_F6BD35E258B5D08C4D0E6DA43E535C81" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_E148A64EC8DBB73404046DA43E539758" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_F6BD35E258B5D08C4D0E6DA43E535C81" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_CaissonInterventionalLLCMember" xlink:label="loc_livn_CaissonInterventionalLLCMember_C6AC56AA20AB7DD7BB116DA43E54A9DB" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_F6BD35E258B5D08C4D0E6DA43E535C81" xlink:to="loc_livn_CaissonInterventionalLLCMember_C6AC56AA20AB7DD7BB116DA43E54A9DB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_DDFC3E6F7952B9D048286DA43E54BBB9" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_EECC063294161D5C2D336DA43E53B9DE" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_DDFC3E6F7952B9D048286DA43E54BBB9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_40D69D0865FB3F4E02C76DA43E5436F3_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_DDFC3E6F7952B9D048286DA43E54BBB9" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_40D69D0865FB3F4E02C76DA43E5436F3_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_40D69D0865FB3F4E02C76DA43E5436F3" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_DDFC3E6F7952B9D048286DA43E54BBB9" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_40D69D0865FB3F4E02C76DA43E5436F3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_446E9C4C8ED90E4D7A5B6DA832B51186" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_58D6221673F492E805056DA43E540BEC" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_446E9C4C8ED90E4D7A5B6DA832B51186" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_AA9078218E004F19CCF06DA43E54B4D8" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_446E9C4C8ED90E4D7A5B6DA832B51186" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_AA9078218E004F19CCF06DA43E54B4D8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityPurchases" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityPurchases_586E88A4E587B57E67076DA43E548802" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_446E9C4C8ED90E4D7A5B6DA832B51186" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityPurchases_586E88A4E587B57E67076DA43E548802" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements_24706754EBD52614C7306DA54B3B5E70" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_446E9C4C8ED90E4D7A5B6DA832B51186" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements_24706754EBD52614C7306DA54B3B5E70" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings_73766E46DBF9B94B9CEA6DA6B60D334C" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_446E9C4C8ED90E4D7A5B6DA832B51186" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings_73766E46DBF9B94B9CEA6DA6B60D334C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInOtherComprehensiveIncome" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInOtherComprehensiveIncome_20637056E19597A0D5D26DA72ADF96CE" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_446E9C4C8ED90E4D7A5B6DA832B51186" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInOtherComprehensiveIncome_20637056E19597A0D5D26DA72ADF96CE" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/AcquisitionsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_8B1A33526812D93558C765B053EEA708" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_636D82E0C38D3FC0D87F65B053E8AA31" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_8B1A33526812D93558C765B053EEA708" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_636D82E0C38D3FC0D87F65B053E8AA31" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_210BC352BEDB33B3F83B65B053E84F86" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_636D82E0C38D3FC0D87F65B053E8AA31" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_210BC352BEDB33B3F83B65B053E84F86" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_FD54D4529EF3E8F510B865B053E89076_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_210BC352BEDB33B3F83B65B053E84F86" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_FD54D4529EF3E8F510B865B053E89076_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_FD54D4529EF3E8F510B865B053E89076" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_210BC352BEDB33B3F83B65B053E84F86" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_FD54D4529EF3E8F510B865B053E89076" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpensesMember" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_AE0B8A693CCD657660D865B053E80D1C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_FD54D4529EF3E8F510B865B053E89076" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_AE0B8A693CCD657660D865B053E80D1C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_F37AEBDB43C7BC3073BD65B053E813A2" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_636D82E0C38D3FC0D87F65B053E8AA31" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_F37AEBDB43C7BC3073BD65B053E813A2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_8C785CF8F84B77FF381F65B053E87768_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_F37AEBDB43C7BC3073BD65B053E813A2" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_8C785CF8F84B77FF381F65B053E87768_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_8C785CF8F84B77FF381F65B053E87768" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_F37AEBDB43C7BC3073BD65B053E813A2" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_8C785CF8F84B77FF381F65B053E87768" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_CaissonInterventionalLLCMember" xlink:label="loc_livn_CaissonInterventionalLLCMember_39A5E26C7B0BC96E621F65B053E8C8E2" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_8C785CF8F84B77FF381F65B053E87768" xlink:to="loc_livn_CaissonInterventionalLLCMember_39A5E26C7B0BC96E621F65B053E8C8E2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementScenarioAxis" xlink:label="loc_us-gaap_StatementScenarioAxis_95B274CEE631F3DAE51D65B053E86942" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_636D82E0C38D3FC0D87F65B053E8AA31" xlink:to="loc_us-gaap_StatementScenarioAxis_95B274CEE631F3DAE51D65B053E86942" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScenarioUnspecifiedDomain" xlink:label="loc_us-gaap_ScenarioUnspecifiedDomain_24D0AA7E0604B2F7144465B053EE82CD_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementScenarioAxis_95B274CEE631F3DAE51D65B053E86942" xlink:to="loc_us-gaap_ScenarioUnspecifiedDomain_24D0AA7E0604B2F7144465B053EE82CD_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScenarioUnspecifiedDomain" xlink:label="loc_us-gaap_ScenarioUnspecifiedDomain_24D0AA7E0604B2F7144465B053EE82CD" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementScenarioAxis_95B274CEE631F3DAE51D65B053E86942" xlink:to="loc_us-gaap_ScenarioUnspecifiedDomain_24D0AA7E0604B2F7144465B053EE82CD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScenarioForecastMember" xlink:label="loc_us-gaap_ScenarioForecastMember_7BA60B463E7FBDD02BEC65B053EEC572" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScenarioUnspecifiedDomain_24D0AA7E0604B2F7144465B053EE82CD" xlink:to="loc_us-gaap_ScenarioForecastMember_7BA60B463E7FBDD02BEC65B053EEC572" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BalanceSheetLocationAxis" xlink:label="loc_us-gaap_BalanceSheetLocationAxis_39E571CE2B8F804EFC1965B053EEFD2A" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_636D82E0C38D3FC0D87F65B053E8AA31" xlink:to="loc_us-gaap_BalanceSheetLocationAxis_39E571CE2B8F804EFC1965B053EEFD2A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BalanceSheetLocationDomain" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_D27A6BC2F31EC3F79D8D65B053EEFB7D_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_39E571CE2B8F804EFC1965B053EEFD2A" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_D27A6BC2F31EC3F79D8D65B053EEFB7D_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BalanceSheetLocationDomain" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_D27A6BC2F31EC3F79D8D65B053EEFB7D" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_39E571CE2B8F804EFC1965B053EEFD2A" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_D27A6BC2F31EC3F79D8D65B053EEFB7D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PrepaidExpensesAndOtherCurrentAssetsMember" xlink:label="loc_us-gaap_PrepaidExpensesAndOtherCurrentAssetsMember_053CB4657EFA51D9D03265B053EE4AF1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_D27A6BC2F31EC3F79D8D65B053EEFB7D" xlink:to="loc_us-gaap_PrepaidExpensesAndOtherCurrentAssetsMember_053CB4657EFA51D9D03265B053EE4AF1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherNoncurrentAssetsMember" xlink:label="loc_us-gaap_OtherNoncurrentAssetsMember_6C8B39070A3E0F79D6EE65B053EEBD3A" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_D27A6BC2F31EC3F79D8D65B053EEFB7D" xlink:to="loc_us-gaap_OtherNoncurrentAssetsMember_6C8B39070A3E0F79D6EE65B053EEBD3A" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_BusinessCombinationEquityInterestinAcquireePercentage" xlink:label="loc_livn_BusinessCombinationEquityInterestinAcquireePercentage_44B66A736B7E0F2465CC65B053EE3FC0" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_8B1A33526812D93558C765B053EEA708" xlink:to="loc_livn_BusinessCombinationEquityInterestinAcquireePercentage_44B66A736B7E0F2465CC65B053EE3FC0" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_BusinessCombinationConsiderationTransferredGross" xlink:label="loc_livn_BusinessCombinationConsiderationTransferredGross_0909A474C4797D750BC265B053EE5F6A" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_8B1A33526812D93558C765B053EEA708" xlink:to="loc_livn_BusinessCombinationConsiderationTransferredGross_0909A474C4797D750BC265B053EE5F6A" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_BusinessCombinationDebtInstrumentDecreaseForgiveness" xlink:label="loc_livn_BusinessCombinationDebtInstrumentDecreaseForgiveness_54C9F5B55966E5E1FF2E65B053EE9E8F" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_8B1A33526812D93558C765B053EEA708" xlink:to="loc_livn_BusinessCombinationDebtInstrumentDecreaseForgiveness_54C9F5B55966E5E1FF2E65B053EE9E8F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesGross" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesGross_CCFBF572F744CFF4DC7965B053EE8086" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_8B1A33526812D93558C765B053EEA708" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesGross_CCFBF572F744CFF4DC7965B053EE8086" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh_4A700CA63C0BA1021EF165B053EEEC6C" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_8B1A33526812D93558C765B053EEA708" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh_4A700CA63C0BA1021EF165B053EEEC6C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionPurchasePriceAllocationGoodwillExpectedTaxDeductibleAmount" xlink:label="loc_us-gaap_BusinessAcquisitionPurchasePriceAllocationGoodwillExpectedTaxDeductibleAmount_8B5FB71C4FA7A75A4D4065B053EE4147" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_8B1A33526812D93558C765B053EEA708" xlink:to="loc_us-gaap_BusinessAcquisitionPurchasePriceAllocationGoodwillExpectedTaxDeductibleAmount_8B5FB71C4FA7A75A4D4065B053EE4147" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationIndemnificationAssetsAmountAsOfAcquisitionDate" xlink:label="loc_us-gaap_BusinessCombinationIndemnificationAssetsAmountAsOfAcquisitionDate_310D8297A1CF11213A2065B053EE8F3E" xlink:type="locator" />
    <link:definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_8B1A33526812D93558C765B053EEA708" xlink:to="loc_us-gaap_BusinessCombinationIndemnificationAssetsAmountAsOfAcquisitionDate_310D8297A1CF11213A2065B053EE8F3E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationAcquisitionRelatedCosts" xlink:label="loc_us-gaap_BusinessCombinationAcquisitionRelatedCosts_2FA8B77B6D199E1B740C65B053EE59D5" xlink:type="locator" />
    <link:definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_8B1A33526812D93558C765B053EEA708" xlink:to="loc_us-gaap_BusinessCombinationAcquisitionRelatedCosts_2FA8B77B6D199E1B740C65B053EE59D5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationProFormaInformationRevenueOfAcquireeSinceAcquisitionDateActual" xlink:label="loc_us-gaap_BusinessCombinationProFormaInformationRevenueOfAcquireeSinceAcquisitionDateActual_909F27D7963CF03925B965B053EEC098" xlink:type="locator" />
    <link:definitionArc order="9" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_8B1A33526812D93558C765B053EEA708" xlink:to="loc_us-gaap_BusinessCombinationProFormaInformationRevenueOfAcquireeSinceAcquisitionDateActual_909F27D7963CF03925B965B053EEC098" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationProFormaInformationEarningsOrLossOfAcquireeSinceAcquisitionDateActual" xlink:label="loc_us-gaap_BusinessCombinationProFormaInformationEarningsOrLossOfAcquireeSinceAcquisitionDateActual_91F55E69484D7B977BB765B053EF454F" xlink:type="locator" />
    <link:definitionArc order="10" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_8B1A33526812D93558C765B053EEA708" xlink:to="loc_us-gaap_BusinessCombinationProFormaInformationEarningsOrLossOfAcquireeSinceAcquisitionDateActual_91F55E69484D7B977BB765B053EF454F" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/AcquisitionsPreliminaryPurchasePriceAllocationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_58FE4488F80D5D9A82B5C23B87C6AF2F" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_5A7438092FDC5068B1F5DFC41FE857A8" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_58FE4488F80D5D9A82B5C23B87C6AF2F" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_5A7438092FDC5068B1F5DFC41FE857A8" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_8BA610A0CF245A1BAB8C5DCAD319722B" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_5A7438092FDC5068B1F5DFC41FE857A8" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_8BA610A0CF245A1BAB8C5DCAD319722B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_17147F5FFB48814AD1B8C4FEBA76AAE9_BEECA28EC1465A3CB0E29196CA2C2F8C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_8BA610A0CF245A1BAB8C5DCAD319722B" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_17147F5FFB48814AD1B8C4FEBA76AAE9_BEECA28EC1465A3CB0E29196CA2C2F8C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_F5C03A7B4F4B58E89C924AE8B635A86C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_8BA610A0CF245A1BAB8C5DCAD319722B" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_F5C03A7B4F4B58E89C924AE8B635A86C" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_CaissonInterventionalLLCMember" xlink:label="loc_livn_CaissonInterventionalLLCMember_EF16F61F68265B8E9F83A236483A17A1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_F5C03A7B4F4B58E89C924AE8B635A86C" xlink:to="loc_livn_CaissonInterventionalLLCMember_EF16F61F68265B8E9F83A236483A17A1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_446B942E50475ECC90303B89011D1CCD" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_58FE4488F80D5D9A82B5C23B87C6AF2F" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_446B942E50475ECC90303B89011D1CCD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibles" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibles_4BD88DE13AAE5612A399A86F494C0F04" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_58FE4488F80D5D9A82B5C23B87C6AF2F" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibles_4BD88DE13AAE5612A399A86F494C0F04" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_94422D12FF1558E08CA1A5291317A8CD" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_58FE4488F80D5D9A82B5C23B87C6AF2F" xlink:to="loc_us-gaap_Goodwill_94422D12FF1558E08CA1A5291317A8CD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherNoncurrentAssets" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherNoncurrentAssets_6E1A79ED284E561B8B5023E9173D5688" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_58FE4488F80D5D9A82B5C23B87C6AF2F" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedOtherNoncurrentAssets_6E1A79ED284E561B8B5023E9173D5688" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilities" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilities_380CA589587E5EEA8E3314873076C92C" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_58FE4488F80D5D9A82B5C23B87C6AF2F" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilities_380CA589587E5EEA8E3314873076C92C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities_54AE91166F455D6E8801E14850AB3866" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_58FE4488F80D5D9A82B5C23B87C6AF2F" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities_54AE91166F455D6E8801E14850AB3866" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_0563BCD45CD257A5BBD2743C29DF1CC7" xlink:type="locator" />
    <link:definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_58FE4488F80D5D9A82B5C23B87C6AF2F" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_0563BCD45CD257A5BBD2743C29DF1CC7" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/AcquisitionsPurchasePriceCompositionDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_B01B31BC823E6A9FE3EF7466210E75D6" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_CF0DDB41CDE0EC8D58437466210C21F5" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_B01B31BC823E6A9FE3EF7466210E75D6" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_CF0DDB41CDE0EC8D58437466210C21F5" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_53D729A68C0ED7F437807466210DC865" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_CF0DDB41CDE0EC8D58437466210C21F5" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_53D729A68C0ED7F437807466210DC865" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_8C845A611C843B6347DA7466210D0280_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_53D729A68C0ED7F437807466210DC865" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_8C845A611C843B6347DA7466210D0280_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_8C845A611C843B6347DA7466210D0280" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_53D729A68C0ED7F437807466210DC865" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_8C845A611C843B6347DA7466210D0280" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_CaissonInterventionalLLCMember" xlink:label="loc_livn_CaissonInterventionalLLCMember_8700239ACF9FBD5C42CE7466210DFFE4" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_8C845A611C843B6347DA7466210D0280" xlink:to="loc_livn_CaissonInterventionalLLCMember_8700239ACF9FBD5C42CE7466210DFFE4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" xlink:label="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_8EAAF8D27049C2ABFB347466210DD6B3" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_CF0DDB41CDE0EC8D58437466210C21F5" xlink:to="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_8EAAF8D27049C2ABFB347466210DD6B3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RelatedPartyDomain" xlink:label="loc_us-gaap_RelatedPartyDomain_9967AA550FF6FB7D14437466210ED2A6_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_8EAAF8D27049C2ABFB347466210DD6B3" xlink:to="loc_us-gaap_RelatedPartyDomain_9967AA550FF6FB7D14437466210ED2A6_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RelatedPartyDomain" xlink:label="loc_us-gaap_RelatedPartyDomain_9967AA550FF6FB7D14437466210ED2A6" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_8EAAF8D27049C2ABFB347466210DD6B3" xlink:to="loc_us-gaap_RelatedPartyDomain_9967AA550FF6FB7D14437466210ED2A6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquityMethodInvesteeMember" xlink:label="loc_us-gaap_EquityMethodInvesteeMember_F358AEDE0290C3080A367466210ECBD4" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RelatedPartyDomain_9967AA550FF6FB7D14437466210ED2A6" xlink:to="loc_us-gaap_EquityMethodInvesteeMember_F358AEDE0290C3080A367466210ECBD4" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_PaymentstoAcquireBusinesses" xlink:label="loc_livn_PaymentstoAcquireBusinesses_904D4FE06C624FA9F23D7466210E7702" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_B01B31BC823E6A9FE3EF7466210E75D6" xlink:to="loc_livn_PaymentstoAcquireBusinesses_904D4FE06C624FA9F23D7466210E7702" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_BusinessCombinationDebtInstrumentDecreaseForgiveness" xlink:label="loc_livn_BusinessCombinationDebtInstrumentDecreaseForgiveness_6E9EC7D1B6B204CAC3917466210E6738" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_B01B31BC823E6A9FE3EF7466210E75D6" xlink:to="loc_livn_BusinessCombinationDebtInstrumentDecreaseForgiveness_6E9EC7D1B6B204CAC3917466210E6738" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_BusinessCombinationDeferredConsideration" xlink:label="loc_livn_BusinessCombinationDeferredConsideration_5D55D624EE7C12C8221C7466210EBAC3" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_B01B31BC823E6A9FE3EF7466210E75D6" xlink:to="loc_livn_BusinessCombinationDeferredConsideration_5D55D624EE7C12C8221C7466210EBAC3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationAssetNoncurrent" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationAssetNoncurrent_B1CE84EFBC1868E198AE7466210E60D9" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_B01B31BC823E6A9FE3EF7466210E75D6" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationAssetNoncurrent_B1CE84EFBC1868E198AE7466210E60D9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferred1" xlink:label="loc_us-gaap_BusinessCombinationConsiderationTransferred1_75D4821A064B8A5897A67466210ECC55" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_B01B31BC823E6A9FE3EF7466210E75D6" xlink:to="loc_us-gaap_BusinessCombinationConsiderationTransferred1_75D4821A064B8A5897A67466210ECC55" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferredIncludingEquityInterestInAcquireeHeldPriorToCombination1" xlink:label="loc_us-gaap_BusinessCombinationConsiderationTransferredIncludingEquityInterestInAcquireeHeldPriorToCombination1_096F4FC272E6FAE7D4517466210EB2CD" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_B01B31BC823E6A9FE3EF7466210E75D6" xlink:to="loc_us-gaap_BusinessCombinationConsiderationTransferredIncludingEquityInterestInAcquireeHeldPriorToCombination1_096F4FC272E6FAE7D4517466210EB2CD" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_BusinessCombinationConsiderationTransferredEquityInterestinAcquireeHeldAfterCombination" xlink:label="loc_livn_BusinessCombinationConsiderationTransferredEquityInterestinAcquireeHeldAfterCombination_DB97022A0931DE3E7F0B7466210E6506" xlink:type="locator" />
    <link:definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_B01B31BC823E6A9FE3EF7466210E75D6" xlink:to="loc_livn_BusinessCombinationConsiderationTransferredEquityInterestinAcquireeHeldAfterCombination_DB97022A0931DE3E7F0B7466210E6506" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_PostCombinationCompensationExpense" xlink:label="loc_livn_PostCombinationCompensationExpense_CFFBFEC0BCCACBAE55597466211128F1" xlink:type="locator" />
    <link:definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_B01B31BC823E6A9FE3EF7466210E75D6" xlink:to="loc_livn_PostCombinationCompensationExpense_CFFBFEC0BCCACBAE55597466211128F1" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_PostCombinationCompensationExpenseWhichReducedCashPaidatClosingofAcquisition" xlink:label="loc_livn_PostCombinationCompensationExpenseWhichReducedCashPaidatClosingofAcquisition_43DDE3F030BD26EABD297466211165FE" xlink:type="locator" />
    <link:definitionArc order="9" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_B01B31BC823E6A9FE3EF7466210E75D6" xlink:to="loc_livn_PostCombinationCompensationExpenseWhichReducedCashPaidatClosingofAcquisition_43DDE3F030BD26EABD297466211165FE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesGross" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesGross_DB8409E31372CD0BACB374662111A4D3" xlink:type="locator" />
    <link:definitionArc order="10" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_B01B31BC823E6A9FE3EF7466210E75D6" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesGross_DB8409E31372CD0BACB374662111A4D3" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_PostCombinationDeferredCompensationandContingentConsiderationRecognizedatDateofAcquisition" xlink:label="loc_livn_PostCombinationDeferredCompensationandContingentConsiderationRecognizedatDateofAcquisition_E0110823B8D09C4B9E0974662112C93D" xlink:type="locator" />
    <link:definitionArc order="11" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_B01B31BC823E6A9FE3EF7466210E75D6" xlink:to="loc_livn_PostCombinationDeferredCompensationandContingentConsiderationRecognizedatDateofAcquisition_E0110823B8D09C4B9E0974662112C93D" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_DeferredCompensationLiabilityAssumedinAcquisition" xlink:label="loc_livn_DeferredCompensationLiabilityAssumedinAcquisition_EEFEB913165727F0B39A74662112149A" xlink:type="locator" />
    <link:definitionArc order="12" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_B01B31BC823E6A9FE3EF7466210E75D6" xlink:to="loc_livn_DeferredCompensationLiabilityAssumedinAcquisition_EEFEB913165727F0B39A74662112149A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_FDF55EB71DEF77AF76267466211282DE" xlink:type="locator" />
    <link:definitionArc order="13" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_B01B31BC823E6A9FE3EF7466210E75D6" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_FDF55EB71DEF77AF76267466211282DE" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentNotesReceivable" xlink:label="loc_livn_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentNotesReceivable_4044072BC46A20389930746621129B3B" xlink:type="locator" />
    <link:definitionArc order="14" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_B01B31BC823E6A9FE3EF7466210E75D6" xlink:to="loc_livn_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentNotesReceivable_4044072BC46A20389930746621129B3B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetsFairValueAdjustment" xlink:label="loc_us-gaap_AssetsFairValueAdjustment_67570C21E33BA44C9A3A746621122B7F" xlink:type="locator" />
    <link:definitionArc order="15" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_B01B31BC823E6A9FE3EF7466210E75D6" xlink:to="loc_us-gaap_AssetsFairValueAdjustment_67570C21E33BA44C9A3A746621122B7F" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/AcquisitionsTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/CommitmentsAndContingencies" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/CommitmentsAndContingenciesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherCommitmentsLineItems" xlink:label="loc_us-gaap_OtherCommitmentsLineItems_BF8A8DF2F610ECBF636F5A39674DD1EC" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherCommitmentsTable" xlink:label="loc_us-gaap_OtherCommitmentsTable_34C2331143DBED7DD6125A39674CA783" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_BF8A8DF2F610ECBF636F5A39674DD1EC" xlink:to="loc_us-gaap_OtherCommitmentsTable_34C2331143DBED7DD6125A39674CA783" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LitigationCaseAxis" xlink:label="loc_us-gaap_LitigationCaseAxis_546B944D70BD21BF6BA75A39674CC492" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_OtherCommitmentsTable_34C2331143DBED7DD6125A39674CA783" xlink:to="loc_us-gaap_LitigationCaseAxis_546B944D70BD21BF6BA75A39674CC492" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LitigationCaseTypeDomain" xlink:label="loc_us-gaap_LitigationCaseTypeDomain_491A910449092DEEB6185A39674C4C40_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LitigationCaseAxis_546B944D70BD21BF6BA75A39674CC492" xlink:to="loc_us-gaap_LitigationCaseTypeDomain_491A910449092DEEB6185A39674C4C40_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LitigationCaseTypeDomain" xlink:label="loc_us-gaap_LitigationCaseTypeDomain_491A910449092DEEB6185A39674C4C40" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LitigationCaseAxis_546B944D70BD21BF6BA75A39674CC492" xlink:to="loc_us-gaap_LitigationCaseTypeDomain_491A910449092DEEB6185A39674C4C40" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_FDAWarningLetterMember" xlink:label="loc_livn_FDAWarningLetterMember_9BE5AA020B07417329B85A39674C3CD1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LitigationCaseTypeDomain_491A910449092DEEB6185A39674C4C40" xlink:to="loc_livn_FDAWarningLetterMember_9BE5AA020B07417329B85A39674C3CD1" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_SNIAMember" xlink:label="loc_livn_SNIAMember_5E81941ACE17A62DF39E5A39674D9DCE" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LitigationCaseTypeDomain_491A910449092DEEB6185A39674C4C40" xlink:to="loc_livn_SNIAMember_5E81941ACE17A62DF39E5A39674D9DCE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LitigationStatusAxis" xlink:label="loc_us-gaap_LitigationStatusAxis_9AE4BE797A1874CF41745A39674D592B" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_OtherCommitmentsTable_34C2331143DBED7DD6125A39674CA783" xlink:to="loc_us-gaap_LitigationStatusAxis_9AE4BE797A1874CF41745A39674D592B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LitigationStatusDomain" xlink:label="loc_us-gaap_LitigationStatusDomain_6D4E1526E50AC0861A1F5A39674D1042_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LitigationStatusAxis_9AE4BE797A1874CF41745A39674D592B" xlink:to="loc_us-gaap_LitigationStatusDomain_6D4E1526E50AC0861A1F5A39674D1042_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LitigationStatusDomain" xlink:label="loc_us-gaap_LitigationStatusDomain_6D4E1526E50AC0861A1F5A39674D1042" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LitigationStatusAxis_9AE4BE797A1874CF41745A39674D592B" xlink:to="loc_us-gaap_LitigationStatusDomain_6D4E1526E50AC0861A1F5A39674D1042" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PendingLitigationMember" xlink:label="loc_us-gaap_PendingLitigationMember_A2C56F4C5A1BF351B8CB5A39674DF4C0" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LitigationStatusDomain_6D4E1526E50AC0861A1F5A39674D1042" xlink:to="loc_us-gaap_PendingLitigationMember_A2C56F4C5A1BF351B8CB5A39674DF4C0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SettledLitigationMember" xlink:label="loc_us-gaap_SettledLitigationMember_CC2DACD9C0BB723679E05A39674D1B5F" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LitigationStatusDomain_6D4E1526E50AC0861A1F5A39674D1042" xlink:to="loc_us-gaap_SettledLitigationMember_CC2DACD9C0BB723679E05A39674D1B5F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ThreatenedLitigationMember" xlink:label="loc_us-gaap_ThreatenedLitigationMember_078FE5B761E82FC449C15A39674DC3EE" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LitigationStatusDomain_6D4E1526E50AC0861A1F5A39674D1042" xlink:to="loc_us-gaap_ThreatenedLitigationMember_078FE5B761E82FC449C15A39674DC3EE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_LegalEntityAxis" xlink:label="loc_dei_LegalEntityAxis_D9C63363A42A05621FFF5A39674DDD79" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_OtherCommitmentsTable_34C2331143DBED7DD6125A39674CA783" xlink:to="loc_dei_LegalEntityAxis_D9C63363A42A05621FFF5A39674DDD79" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityDomain" xlink:label="loc_dei_EntityDomain_B7B5A7FB6DF7CA168C1B5A39674D78E0_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_dei_LegalEntityAxis_D9C63363A42A05621FFF5A39674DDD79" xlink:to="loc_dei_EntityDomain_B7B5A7FB6DF7CA168C1B5A39674D78E0_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityDomain" xlink:label="loc_dei_EntityDomain_B7B5A7FB6DF7CA168C1B5A39674D78E0" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_dei_LegalEntityAxis_D9C63363A42A05621FFF5A39674DDD79" xlink:to="loc_dei_EntityDomain_B7B5A7FB6DF7CA168C1B5A39674D78E0" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_SorinS.p.A.Member" xlink:label="loc_livn_SorinS.p.A.Member_6230FD22857B4257EC845A39674DA233" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityDomain_B7B5A7FB6DF7CA168C1B5A39674D78E0" xlink:to="loc_livn_SorinS.p.A.Member_6230FD22857B4257EC845A39674DA233" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_SNIAs.p.aMember" xlink:label="loc_livn_SNIAs.p.aMember_15A55CB54EC46E8078275A39674D81F6" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityDomain_B7B5A7FB6DF7CA168C1B5A39674D78E0" xlink:to="loc_livn_SNIAs.p.aMember_15A55CB54EC46E8078275A39674D81F6" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_SorinS.p.A.andSNIAs.p.aMember" xlink:label="loc_livn_SorinS.p.A.andSNIAs.p.aMember_82F17D63F46E2B1B28A85A39674D3138" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityDomain_B7B5A7FB6DF7CA168C1B5A39674D78E0" xlink:to="loc_livn_SorinS.p.A.andSNIAs.p.aMember_82F17D63F46E2B1B28A85A39674D3138" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainContingenciesByNatureAxis" xlink:label="loc_us-gaap_GainContingenciesByNatureAxis_B3E7938BD39BE15FF8325A39674DFDAC" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_OtherCommitmentsTable_34C2331143DBED7DD6125A39674CA783" xlink:to="loc_us-gaap_GainContingenciesByNatureAxis_B3E7938BD39BE15FF8325A39674DFDAC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainContingencyNatureDomain" xlink:label="loc_us-gaap_GainContingencyNatureDomain_E389D50D2D9B539FCADC5A39674DE6EC_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_GainContingenciesByNatureAxis_B3E7938BD39BE15FF8325A39674DFDAC" xlink:to="loc_us-gaap_GainContingencyNatureDomain_E389D50D2D9B539FCADC5A39674DE6EC_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainContingencyNatureDomain" xlink:label="loc_us-gaap_GainContingencyNatureDomain_E389D50D2D9B539FCADC5A39674DE6EC" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_GainContingenciesByNatureAxis_B3E7938BD39BE15FF8325A39674DFDAC" xlink:to="loc_us-gaap_GainContingencyNatureDomain_E389D50D2D9B539FCADC5A39674DE6EC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PositiveOutcomeOfLitigationMember" xlink:label="loc_us-gaap_PositiveOutcomeOfLitigationMember_B73E00D3A3B67E848B7D5A39674D517A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GainContingencyNatureDomain_E389D50D2D9B539FCADC5A39674DE6EC" xlink:to="loc_us-gaap_PositiveOutcomeOfLitigationMember_B73E00D3A3B67E848B7D5A39674D517A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxAuthorityNameAxis" xlink:label="loc_us-gaap_IncomeTaxAuthorityNameAxis_F2C29E7287FDD95D81A15A39674D35B7" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_OtherCommitmentsTable_34C2331143DBED7DD6125A39674CA783" xlink:to="loc_us-gaap_IncomeTaxAuthorityNameAxis_F2C29E7287FDD95D81A15A39674D35B7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxAuthorityNameDomain" xlink:label="loc_us-gaap_IncomeTaxAuthorityNameDomain_B47817E908DAB261D90F5A39674D03FE_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeTaxAuthorityNameAxis_F2C29E7287FDD95D81A15A39674D35B7" xlink:to="loc_us-gaap_IncomeTaxAuthorityNameDomain_B47817E908DAB261D90F5A39674D03FE_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxAuthorityNameDomain" xlink:label="loc_us-gaap_IncomeTaxAuthorityNameDomain_B47817E908DAB261D90F5A39674D03FE" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeTaxAuthorityNameAxis_F2C29E7287FDD95D81A15A39674D35B7" xlink:to="loc_us-gaap_IncomeTaxAuthorityNameDomain_B47817E908DAB261D90F5A39674D03FE" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_RegionalInternalRevenueOfficeofLombardyMember" xlink:label="loc_livn_RegionalInternalRevenueOfficeofLombardyMember_2FD2E71AE057152AB4775A39674D5092" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxAuthorityNameDomain_B47817E908DAB261D90F5A39674D03FE" xlink:to="loc_livn_RegionalInternalRevenueOfficeofLombardyMember_2FD2E71AE057152AB4775A39674D5092" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_LossContingencyNumberofObservedNonConformities" xlink:label="loc_livn_LossContingencyNumberofObservedNonConformities_78190B2A184A5730CECC5A39674D728F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_BF8A8DF2F610ECBF636F5A39674DD1EC" xlink:to="loc_livn_LossContingencyNumberofObservedNonConformities_78190B2A184A5730CECC5A39674D728F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccrualForEnvironmentalLossContingencies" xlink:label="loc_us-gaap_AccrualForEnvironmentalLossContingencies_8D1885B8B0898E4C37875A39674D2431" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_BF8A8DF2F610ECBF636F5A39674DD1EC" xlink:to="loc_us-gaap_AccrualForEnvironmentalLossContingencies_8D1885B8B0898E4C37875A39674D2431" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StockholdersEquityNoteSpinoffTransaction" xlink:label="loc_us-gaap_StockholdersEquityNoteSpinoffTransaction_446E6F91A86D08E894F15A39674EEA0A" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_BF8A8DF2F610ECBF636F5A39674DD1EC" xlink:to="loc_us-gaap_StockholdersEquityNoteSpinoffTransaction_446E6F91A86D08E894F15A39674EEA0A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LossContingencyDamagesSoughtValue" xlink:label="loc_us-gaap_LossContingencyDamagesSoughtValue_F2342E6D77E4318F57495A39674E85A9" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_BF8A8DF2F610ECBF636F5A39674DD1EC" xlink:to="loc_us-gaap_LossContingencyDamagesSoughtValue_F2342E6D77E4318F57495A39674E85A9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LitigationSettlementAmountAwardedFromOtherParty" xlink:label="loc_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_A9951E71CAE20C590D8A5A39674E4026" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_BF8A8DF2F610ECBF636F5A39674DD1EC" xlink:to="loc_us-gaap_LitigationSettlementAmountAwardedFromOtherParty_A9951E71CAE20C590D8A5A39674E4026" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_ReimbursedLegalFees" xlink:label="loc_livn_ReimbursedLegalFees_EF49655D325010CD66FD5A39674E4870" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_BF8A8DF2F610ECBF636F5A39674DD1EC" xlink:to="loc_livn_ReimbursedLegalFees_EF49655D325010CD66FD5A39674E4870" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_IncomeTaxExaminationOperatingLossesUnderDispute" xlink:label="loc_livn_IncomeTaxExaminationOperatingLossesUnderDispute_4A543F3E621CE31332345A39674E3162" xlink:type="locator" />
    <link:definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_BF8A8DF2F610ECBF636F5A39674DD1EC" xlink:to="loc_livn_IncomeTaxExaminationOperatingLossesUnderDispute_4A543F3E621CE31332345A39674E3162" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_IncomeTaxExaminationNumberofInstallments" xlink:label="loc_livn_IncomeTaxExaminationNumberofInstallments_95FD29F6F79E673BFB725A39674EA449" xlink:type="locator" />
    <link:definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_BF8A8DF2F610ECBF636F5A39674DD1EC" xlink:to="loc_livn_IncomeTaxExaminationNumberofInstallments_95FD29F6F79E673BFB725A39674EA449" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_LossContingencyNumberofAssessments" xlink:label="loc_livn_LossContingencyNumberofAssessments_0B2A408A949B14351F9B5A39674EE7F0" xlink:type="locator" />
    <link:definitionArc order="9" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_BF8A8DF2F610ECBF636F5A39674DD1EC" xlink:to="loc_livn_LossContingencyNumberofAssessments_0B2A408A949B14351F9B5A39674EE7F0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxExaminationEstimateOfPossibleLoss" xlink:label="loc_us-gaap_IncomeTaxExaminationEstimateOfPossibleLoss_960A9BB0B570890D81C55A39674E677E" xlink:type="locator" />
    <link:definitionArc order="10" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_BF8A8DF2F610ECBF636F5A39674DD1EC" xlink:to="loc_us-gaap_IncomeTaxExaminationEstimateOfPossibleLoss_960A9BB0B570890D81C55A39674E677E" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/CondensedConsolidatedBalanceSheets" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/CondensedConsolidatedBalanceSheetsParenthetical" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/CondensedConsolidatedStatementsOfCashFlowsUnaudited" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/CondensedConsolidatedStatementsOfComprehensiveIncomeLossUnaudited" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/CondensedConsolidatedStatementsOfIncomeLossUnaudited" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagement" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementAmountOfGainLossRecognizedInOciAndIncomeStatementDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_FB18A1524D47D2E94B2A4B20EDB1DBE1" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_F182082122A112787DB64B20EDB1494A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_FB18A1524D47D2E94B2A4B20EDB1DBE1" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_F182082122A112787DB64B20EDB1494A" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_C79A511394A1A8B573334B20EDB1DCAC" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_F182082122A112787DB64B20EDB1494A" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_C79A511394A1A8B573334B20EDB1DCAC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HedgingRelationshipDomain" xlink:label="loc_us-gaap_HedgingRelationshipDomain_7427FB5DE6D906B711B94B20EDB16674_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_C79A511394A1A8B573334B20EDB1DCAC" xlink:to="loc_us-gaap_HedgingRelationshipDomain_7427FB5DE6D906B711B94B20EDB16674_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HedgingRelationshipDomain" xlink:label="loc_us-gaap_HedgingRelationshipDomain_7427FB5DE6D906B711B94B20EDB16674" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_C79A511394A1A8B573334B20EDB1DCAC" xlink:to="loc_us-gaap_HedgingRelationshipDomain_7427FB5DE6D906B711B94B20EDB16674" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashFlowHedgingMember" xlink:label="loc_us-gaap_CashFlowHedgingMember_94097D13E380D062C4DD4B20EDB1D77D" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingRelationshipDomain_7427FB5DE6D906B711B94B20EDB16674" xlink:to="loc_us-gaap_CashFlowHedgingMember_94097D13E380D062C4DD4B20EDB1D77D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_56F1E0714226B1343B3F4B20EDB13CB9" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_F182082122A112787DB64B20EDB1494A" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_56F1E0714226B1343B3F4B20EDB13CB9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_628C6B66180E08CFF47B4B20EDB19CF6_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_56F1E0714226B1343B3F4B20EDB13CB9" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_628C6B66180E08CFF47B4B20EDB19CF6_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_628C6B66180E08CFF47B4B20EDB19CF6" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_56F1E0714226B1343B3F4B20EDB13CB9" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_628C6B66180E08CFF47B4B20EDB19CF6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ForeignExchangeContractMember" xlink:label="loc_us-gaap_ForeignExchangeContractMember_D53F4F3FA0626AAE34204B20EDB1C3CA" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_628C6B66180E08CFF47B4B20EDB19CF6" xlink:to="loc_us-gaap_ForeignExchangeContractMember_D53F4F3FA0626AAE34204B20EDB1C3CA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestRateSwapMember" xlink:label="loc_us-gaap_InterestRateSwapMember_3491FA4D0A810A0A6C2B4B20EDB1193B" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_628C6B66180E08CFF47B4B20EDB19CF6" xlink:to="loc_us-gaap_InterestRateSwapMember_3491FA4D0A810A0A6C2B4B20EDB1193B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_4A94861C3F5B7BBED4754B20EDB12EE9" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_F182082122A112787DB64B20EDB1494A" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_4A94861C3F5B7BBED4754B20EDB12EE9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_8F266580859F27432F854B20EDB1B327_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_4A94861C3F5B7BBED4754B20EDB12EE9" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_8F266580859F27432F854B20EDB1B327_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_8F266580859F27432F854B20EDB1B327" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_4A94861C3F5B7BBED4754B20EDB12EE9" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_8F266580859F27432F854B20EDB1B327" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_ForeignExchangeandOtherMember" xlink:label="loc_livn_ForeignExchangeandOtherMember_21A74E0201519B79A4E54B20EDB1F336" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_8F266580859F27432F854B20EDB1B327" xlink:to="loc_livn_ForeignExchangeandOtherMember_21A74E0201519B79A4E54B20EDB1F336" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpensesMember" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_E434A49A35E4D92AB8294B20EDB1A42E" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_8F266580859F27432F854B20EDB1B327" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_E434A49A35E4D92AB8294B20EDB1A42E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestExpenseMember" xlink:label="loc_us-gaap_InterestExpenseMember_B329D01B9D7DBBF754AB4B20EDB162F0" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_8F266580859F27432F854B20EDB1B327" xlink:to="loc_us-gaap_InterestExpenseMember_B329D01B9D7DBBF754AB4B20EDB162F0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossRecognizedInOtherComprehensiveIncomeEffectivePortionNet" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossRecognizedInOtherComprehensiveIncomeEffectivePortionNet_9B89AB41C6A55987CD7A4B20EDB20BC3" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_FB18A1524D47D2E94B2A4B20EDB1DBE1" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossRecognizedInOtherComprehensiveIncomeEffectivePortionNet_9B89AB41C6A55987CD7A4B20EDB20BC3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossReclassifiedFromAccumulatedOCIIntoIncomeEffectivePortionNet" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossReclassifiedFromAccumulatedOCIIntoIncomeEffectivePortionNet_0F9E7F32CFB4E62513E84B20EDB239E1" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_FB18A1524D47D2E94B2A4B20EDB1DBE1" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossReclassifiedFromAccumulatedOCIIntoIncomeEffectivePortionNet_0F9E7F32CFB4E62513E84B20EDB239E1" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementDerivativeNotionalAmountsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeLineItems" xlink:label="loc_us-gaap_DerivativeLineItems_828A3D09FBEC8BA541AA4B20EDB88CCC" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeTable" xlink:label="loc_us-gaap_DerivativeTable_BC5DAF02D81DF73EB3884B20EDB7ED65" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativeLineItems_828A3D09FBEC8BA541AA4B20EDB88CCC" xlink:to="loc_us-gaap_DerivativeTable_BC5DAF02D81DF73EB3884B20EDB7ED65" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HedgingDesignationAxis" xlink:label="loc_us-gaap_HedgingDesignationAxis_11C58AB559711EBB9EC74B20EDB703CB" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_BC5DAF02D81DF73EB3884B20EDB7ED65" xlink:to="loc_us-gaap_HedgingDesignationAxis_11C58AB559711EBB9EC74B20EDB703CB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="loc_us-gaap_HedgingDesignationDomain_FCC2735A2BB18F6452424B20EDB77821_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_HedgingDesignationAxis_11C58AB559711EBB9EC74B20EDB703CB" xlink:to="loc_us-gaap_HedgingDesignationDomain_FCC2735A2BB18F6452424B20EDB77821_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="loc_us-gaap_HedgingDesignationDomain_FCC2735A2BB18F6452424B20EDB77821" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_HedgingDesignationAxis_11C58AB559711EBB9EC74B20EDB703CB" xlink:to="loc_us-gaap_HedgingDesignationDomain_FCC2735A2BB18F6452424B20EDB77821" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DesignatedAsHedgingInstrumentMember" xlink:label="loc_us-gaap_DesignatedAsHedgingInstrumentMember_69E7398D99EAF34FFEDB4B20EDB76A68" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_FCC2735A2BB18F6452424B20EDB77821" xlink:to="loc_us-gaap_DesignatedAsHedgingInstrumentMember_69E7398D99EAF34FFEDB4B20EDB76A68" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_96BE66B9A1E80598C6DB4B20EDB79A3F" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_BC5DAF02D81DF73EB3884B20EDB7ED65" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_96BE66B9A1E80598C6DB4B20EDB79A3F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HedgingRelationshipDomain" xlink:label="loc_us-gaap_HedgingRelationshipDomain_99C15744C596212055464B20EDB77A0C_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_96BE66B9A1E80598C6DB4B20EDB79A3F" xlink:to="loc_us-gaap_HedgingRelationshipDomain_99C15744C596212055464B20EDB77A0C_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HedgingRelationshipDomain" xlink:label="loc_us-gaap_HedgingRelationshipDomain_99C15744C596212055464B20EDB77A0C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_96BE66B9A1E80598C6DB4B20EDB79A3F" xlink:to="loc_us-gaap_HedgingRelationshipDomain_99C15744C596212055464B20EDB77A0C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashFlowHedgingMember" xlink:label="loc_us-gaap_CashFlowHedgingMember_967E3E0D762DD9AEC84B4B20EDB79B79" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingRelationshipDomain_99C15744C596212055464B20EDB77A0C" xlink:to="loc_us-gaap_CashFlowHedgingMember_967E3E0D762DD9AEC84B4B20EDB79B79" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_49BB6A38ED1C3EAC82304B20EDB78B1F" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_BC5DAF02D81DF73EB3884B20EDB7ED65" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_49BB6A38ED1C3EAC82304B20EDB78B1F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_5F75277322E0B6798A2D4B20EDB83A7E_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_49BB6A38ED1C3EAC82304B20EDB78B1F" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_5F75277322E0B6798A2D4B20EDB83A7E_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_5F75277322E0B6798A2D4B20EDB83A7E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_49BB6A38ED1C3EAC82304B20EDB78B1F" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_5F75277322E0B6798A2D4B20EDB83A7E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ForeignExchangeContractMember" xlink:label="loc_us-gaap_ForeignExchangeContractMember_568BA73EF044D03DEC6B4B20EDB894B4" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_5F75277322E0B6798A2D4B20EDB83A7E" xlink:to="loc_us-gaap_ForeignExchangeContractMember_568BA73EF044D03DEC6B4B20EDB894B4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestRateSwapMember" xlink:label="loc_us-gaap_InterestRateSwapMember_8F82742DED750E8DFA244B20EDB82400" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_5F75277322E0B6798A2D4B20EDB83A7E" xlink:to="loc_us-gaap_InterestRateSwapMember_8F82742DED750E8DFA244B20EDB82400" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CurrencyAxis" xlink:label="loc_us-gaap_CurrencyAxis_CFBB118A524B788807694B20EDB8BAFF" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_BC5DAF02D81DF73EB3884B20EDB7ED65" xlink:to="loc_us-gaap_CurrencyAxis_CFBB118A524B788807694B20EDB8BAFF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/currency/2017/currency-2017-01-31.xsd#currency_AllCurrenciesDomain" xlink:label="loc_currency_AllCurrenciesDomain_395DFB21D000BA86FB984B20EDB867E0_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_CurrencyAxis_CFBB118A524B788807694B20EDB8BAFF" xlink:to="loc_currency_AllCurrenciesDomain_395DFB21D000BA86FB984B20EDB867E0_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/currency/2017/currency-2017-01-31.xsd#currency_AllCurrenciesDomain" xlink:label="loc_currency_AllCurrenciesDomain_395DFB21D000BA86FB984B20EDB867E0" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_CurrencyAxis_CFBB118A524B788807694B20EDB8BAFF" xlink:to="loc_currency_AllCurrenciesDomain_395DFB21D000BA86FB984B20EDB867E0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/currency/2017/currency-2017-01-31.xsd#currency_GBP" xlink:label="loc_currency_GBP_5ADEAC1C2910AC8B65644B20EDB84E9B" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_currency_AllCurrenciesDomain_395DFB21D000BA86FB984B20EDB867E0" xlink:to="loc_currency_GBP_5ADEAC1C2910AC8B65644B20EDB84E9B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/currency/2017/currency-2017-01-31.xsd#currency_JPY" xlink:label="loc_currency_JPY_98BD9D5F9E6E2D7DB62D4B20EDB8E3DC" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_currency_AllCurrenciesDomain_395DFB21D000BA86FB984B20EDB867E0" xlink:to="loc_currency_JPY_98BD9D5F9E6E2D7DB62D4B20EDB8E3DC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/currency/2017/currency-2017-01-31.xsd#currency_CAD" xlink:label="loc_currency_CAD_3207E8FC600C53605FA44B20EDB87340" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_currency_AllCurrenciesDomain_395DFB21D000BA86FB984B20EDB867E0" xlink:to="loc_currency_CAD_3207E8FC600C53605FA44B20EDB87340" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/invest/2013/invest-2013-01-31.xsd#invest_DerivativeNotionalAmount" xlink:label="loc_invest_DerivativeNotionalAmount_44DD206BB80674D4FB3C4B20EDB8EF92" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_828A3D09FBEC8BA541AA4B20EDB88CCC" xlink:to="loc_invest_DerivativeNotionalAmount_44DD206BB80674D4FB3C4B20EDB8EF92" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedGainLossOnDerivativesArisingDuringPeriodNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedGainLossOnDerivativesArisingDuringPeriodNetOfTax_D4464424FEFADA3650F44B20EDB84CA8" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_828A3D09FBEC8BA541AA4B20EDB88CCC" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedGainLossOnDerivativesArisingDuringPeriodNetOfTax_D4464424FEFADA3650F44B20EDB84CA8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashFlowHedgeGainLossToBeReclassifiedWithinTwelveMonths" xlink:label="loc_us-gaap_CashFlowHedgeGainLossToBeReclassifiedWithinTwelveMonths_809FD52E597F9AC645D54B20EDB8ABAB" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_828A3D09FBEC8BA541AA4B20EDB88CCC" xlink:to="loc_us-gaap_CashFlowHedgeGainLossToBeReclassifiedWithinTwelveMonths_809FD52E597F9AC645D54B20EDB8ABAB" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementFairValueOfDerivativeInstrumentsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativesFairValueLineItems" xlink:label="loc_us-gaap_DerivativesFairValueLineItems_C7EC9C4D102F5CE978B42FE5D2237FBD" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable" xlink:label="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_54CEF6E044BF470A8AC32FE5D2225BD2" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_C7EC9C4D102F5CE978B42FE5D2237FBD" xlink:to="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_54CEF6E044BF470A8AC32FE5D2225BD2" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HedgingDesignationAxis" xlink:label="loc_us-gaap_HedgingDesignationAxis_732131A0A000DF38506A2FE5D2226C2E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_54CEF6E044BF470A8AC32FE5D2225BD2" xlink:to="loc_us-gaap_HedgingDesignationAxis_732131A0A000DF38506A2FE5D2226C2E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="loc_us-gaap_HedgingDesignationDomain_A1F3FD657A979EE198222FE5D22225EB_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_HedgingDesignationAxis_732131A0A000DF38506A2FE5D2226C2E" xlink:to="loc_us-gaap_HedgingDesignationDomain_A1F3FD657A979EE198222FE5D22225EB_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="loc_us-gaap_HedgingDesignationDomain_A1F3FD657A979EE198222FE5D22225EB" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_HedgingDesignationAxis_732131A0A000DF38506A2FE5D2226C2E" xlink:to="loc_us-gaap_HedgingDesignationDomain_A1F3FD657A979EE198222FE5D22225EB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DesignatedAsHedgingInstrumentMember" xlink:label="loc_us-gaap_DesignatedAsHedgingInstrumentMember_5F6FDFCC8B895C7BBFAA2FE5D222E49B" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_A1F3FD657A979EE198222FE5D22225EB" xlink:to="loc_us-gaap_DesignatedAsHedgingInstrumentMember_5F6FDFCC8B895C7BBFAA2FE5D222E49B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NondesignatedMember" xlink:label="loc_us-gaap_NondesignatedMember_0D35AB407ACA0BCA79892FE5D222F35C" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_A1F3FD657A979EE198222FE5D22225EB" xlink:to="loc_us-gaap_NondesignatedMember_0D35AB407ACA0BCA79892FE5D222F35C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BalanceSheetLocationAxis" xlink:label="loc_us-gaap_BalanceSheetLocationAxis_8D9D992CB2071A32F7962FE5D222B6F0" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_54CEF6E044BF470A8AC32FE5D2225BD2" xlink:to="loc_us-gaap_BalanceSheetLocationAxis_8D9D992CB2071A32F7962FE5D222B6F0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BalanceSheetLocationDomain" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_D4A4EA0B7A936D08E5DA2FE5D2225512_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_8D9D992CB2071A32F7962FE5D222B6F0" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_D4A4EA0B7A936D08E5DA2FE5D2225512_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BalanceSheetLocationDomain" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_D4A4EA0B7A936D08E5DA2FE5D2225512" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_8D9D992CB2071A32F7962FE5D222B6F0" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_D4A4EA0B7A936D08E5DA2FE5D2225512" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PrepaidExpensesAndOtherCurrentAssetsMember" xlink:label="loc_us-gaap_PrepaidExpensesAndOtherCurrentAssetsMember_353927C47E41F9B2E4BA2FE5D2225049" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_D4A4EA0B7A936D08E5DA2FE5D2225512" xlink:to="loc_us-gaap_PrepaidExpensesAndOtherCurrentAssetsMember_353927C47E41F9B2E4BA2FE5D2225049" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccruedLiabilitiesMember" xlink:label="loc_us-gaap_AccruedLiabilitiesMember_9CE4D1FE07872F9A6F0E2FE5D2227E5B" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_D4A4EA0B7A936D08E5DA2FE5D2225512" xlink:to="loc_us-gaap_AccruedLiabilitiesMember_9CE4D1FE07872F9A6F0E2FE5D2227E5B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherAssetsMember" xlink:label="loc_us-gaap_OtherAssetsMember_5DA5976E5DABCCF56CA22FE5D222D815" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_D4A4EA0B7A936D08E5DA2FE5D2225512" xlink:to="loc_us-gaap_OtherAssetsMember_5DA5976E5DABCCF56CA22FE5D222D815" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherNoncurrentLiabilitiesMember" xlink:label="loc_us-gaap_OtherNoncurrentLiabilitiesMember_7AAE3B0E10BD7EADD1032FE5D2223734" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_D4A4EA0B7A936D08E5DA2FE5D2225512" xlink:to="loc_us-gaap_OtherNoncurrentLiabilitiesMember_7AAE3B0E10BD7EADD1032FE5D2223734" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_78C3EB8DE9668EB273A52FE5D2226364" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_54CEF6E044BF470A8AC32FE5D2225BD2" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_78C3EB8DE9668EB273A52FE5D2226364" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_0F1B8C4FE12C1BDF5B952FE5D2230B06_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_78C3EB8DE9668EB273A52FE5D2226364" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_0F1B8C4FE12C1BDF5B952FE5D2230B06_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_0F1B8C4FE12C1BDF5B952FE5D2230B06" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_78C3EB8DE9668EB273A52FE5D2226364" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_0F1B8C4FE12C1BDF5B952FE5D2230B06" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestRateContractMember" xlink:label="loc_us-gaap_InterestRateContractMember_E0768BC41CCAA5F93B182FE5D2230311" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_0F1B8C4FE12C1BDF5B952FE5D2230B06" xlink:to="loc_us-gaap_InterestRateContractMember_E0768BC41CCAA5F93B182FE5D2230311" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ForeignExchangeContractMember" xlink:label="loc_us-gaap_ForeignExchangeContractMember_9A2FE5A187480A067C382FE5D2230151" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_0F1B8C4FE12C1BDF5B952FE5D2230B06" xlink:to="loc_us-gaap_ForeignExchangeContractMember_9A2FE5A187480A067C382FE5D2230151" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeAsset" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeAsset_B27C6C02FB499C5732262FE5D2238FFD" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_C7EC9C4D102F5CE978B42FE5D2237FBD" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeAsset_B27C6C02FB499C5732262FE5D2238FFD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeLiability" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_8F27E839A5B7171AEB5C2FE5D223F592" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_C7EC9C4D102F5CE978B42FE5D2237FBD" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_8F27E839A5B7171AEB5C2FE5D223F592" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeLineItems" xlink:label="loc_us-gaap_DerivativeLineItems_FBEA333F813763B0273879101D823C51" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeTable" xlink:label="loc_us-gaap_DerivativeTable_C0B9B9F0CFDA6B254C3179101D820804" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativeLineItems_FBEA333F813763B0273879101D823C51" xlink:to="loc_us-gaap_DerivativeTable_C0B9B9F0CFDA6B254C3179101D820804" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HedgingDesignationAxis" xlink:label="loc_us-gaap_HedgingDesignationAxis_B36DA12A9DA1B7C48A8779101D821B89" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_C0B9B9F0CFDA6B254C3179101D820804" xlink:to="loc_us-gaap_HedgingDesignationAxis_B36DA12A9DA1B7C48A8779101D821B89" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="loc_us-gaap_HedgingDesignationDomain_3F25AAA615930FBFF41579101D8214C0_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_HedgingDesignationAxis_B36DA12A9DA1B7C48A8779101D821B89" xlink:to="loc_us-gaap_HedgingDesignationDomain_3F25AAA615930FBFF41579101D8214C0_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="loc_us-gaap_HedgingDesignationDomain_3F25AAA615930FBFF41579101D8214C0" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_HedgingDesignationAxis_B36DA12A9DA1B7C48A8779101D821B89" xlink:to="loc_us-gaap_HedgingDesignationDomain_3F25AAA615930FBFF41579101D8214C0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NondesignatedMember" xlink:label="loc_us-gaap_NondesignatedMember_5FA88EE5F482730B057979101D82C554" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_3F25AAA615930FBFF41579101D8214C0" xlink:to="loc_us-gaap_NondesignatedMember_5FA88EE5F482730B057979101D82C554" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_6BC499EF30B0C6A23F2279101D82B54F" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_C0B9B9F0CFDA6B254C3179101D820804" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_6BC499EF30B0C6A23F2279101D82B54F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_1EE534ABCA7415B490A379101D82C9B5_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_6BC499EF30B0C6A23F2279101D82B54F" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_1EE534ABCA7415B490A379101D82C9B5_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_1EE534ABCA7415B490A379101D82C9B5" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_6BC499EF30B0C6A23F2279101D82B54F" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_1EE534ABCA7415B490A379101D82C9B5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ForeignExchangeForwardMember" xlink:label="loc_us-gaap_ForeignExchangeForwardMember_389F6F892BB1EC1E450C79101D82E7CB" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_1EE534ABCA7415B490A379101D82C9B5" xlink:to="loc_us-gaap_ForeignExchangeForwardMember_389F6F892BB1EC1E450C79101D82E7CB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ForeignExchangeContractMember" xlink:label="loc_us-gaap_ForeignExchangeContractMember_EC15176BEEE44AF1449E79101D82AD11" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_1EE534ABCA7415B490A379101D82C9B5" xlink:to="loc_us-gaap_ForeignExchangeContractMember_EC15176BEEE44AF1449E79101D82AD11" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_11C03331A9AB56142A0079101D82DDDB" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_C0B9B9F0CFDA6B254C3179101D820804" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_11C03331A9AB56142A0079101D82DDDB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_8C0C836713AD652C453779101D8287C1_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_11C03331A9AB56142A0079101D82DDDB" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_8C0C836713AD652C453779101D8287C1_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_8C0C836713AD652C453779101D8287C1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_11C03331A9AB56142A0079101D82DDDB" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_8C0C836713AD652C453779101D8287C1" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_ForeignExchangeandOtherMember" xlink:label="loc_livn_ForeignExchangeandOtherMember_315B3BF0B23D1802545579101D82A68F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_8C0C836713AD652C453779101D8287C1" xlink:to="loc_livn_ForeignExchangeandOtherMember_315B3BF0B23D1802545579101D82A68F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/invest/2013/invest-2013-01-31.xsd#invest_DerivativeNotionalAmount" xlink:label="loc_invest_DerivativeNotionalAmount_75472FA7D496979634E879101D8287CC" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_FBEA333F813763B0273879101D823C51" xlink:to="loc_invest_DerivativeNotionalAmount_75472FA7D496979634E879101D8287CC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeGainLossOnDerivativeNet" xlink:label="loc_us-gaap_DerivativeGainLossOnDerivativeNet_FED023AC55A9EE65CBDB79101D83981C" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_FBEA333F813763B0273879101D823C51" xlink:to="loc_us-gaap_DerivativeGainLossOnDerivativeNet_FED023AC55A9EE65CBDB79101D83981C" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/DocumentAndEntityInformation" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/FairValueMeasurements" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/FairValueMeasurementsAssetsAndLiabilitiesThatAreMeasuredAtFairValueOnRecurringBasisDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_2B614B749330D4595FC16DA43DF9D946" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_12BDBE6FB3816CF6F1536DA43DF8B55D" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_2B614B749330D4595FC16DA43DF9D946" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_12BDBE6FB3816CF6F1536DA43DF8B55D" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_6FAC9E5E17403D344F196DA43DF8B23A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_12BDBE6FB3816CF6F1536DA43DF8B55D" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_6FAC9E5E17403D344F196DA43DF8B23A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_18D7C424D4BE52ED656D6DA43DF83142_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_6FAC9E5E17403D344F196DA43DF8B23A" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_18D7C424D4BE52ED656D6DA43DF83142_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_18D7C424D4BE52ED656D6DA43DF83142" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_6FAC9E5E17403D344F196DA43DF8B23A" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_18D7C424D4BE52ED656D6DA43DF83142" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementsRecurringMember" xlink:label="loc_us-gaap_FairValueMeasurementsRecurringMember_7B1B966C4DDD9EE89D296DA43DF8547D" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_18D7C424D4BE52ED656D6DA43DF83142" xlink:to="loc_us-gaap_FairValueMeasurementsRecurringMember_7B1B966C4DDD9EE89D296DA43DF8547D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_90F0D07237E46FC46D9F6DA43DF8525F" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_12BDBE6FB3816CF6F1536DA43DF8B55D" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_90F0D07237E46FC46D9F6DA43DF8525F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_FC9311F627BF8797748F6DA43DF88B67_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_90F0D07237E46FC46D9F6DA43DF8525F" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_FC9311F627BF8797748F6DA43DF88B67_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_FC9311F627BF8797748F6DA43DF88B67" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_90F0D07237E46FC46D9F6DA43DF8525F" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_FC9311F627BF8797748F6DA43DF88B67" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueInputsLevel1Member" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_FC3EEB8650ED1E97356E6DA43DF9D9C1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_FC9311F627BF8797748F6DA43DF88B67" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_FC3EEB8650ED1E97356E6DA43DF9D9C1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueInputsLevel2Member" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_02B62705CCFAFDFE25536DA43DF96930" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_FC9311F627BF8797748F6DA43DF88B67" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_02B62705CCFAFDFE25536DA43DF96930" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FairValueInputsLevel3Member" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_BB6DAD366F1804B180EB6DA43DF9E0BB" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_FC9311F627BF8797748F6DA43DF88B67" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_BB6DAD366F1804B180EB6DA43DF9E0BB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HedgingDesignationAxis" xlink:label="loc_us-gaap_HedgingDesignationAxis_A46A13B33348215BF2396DA43DF9E0AD" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_12BDBE6FB3816CF6F1536DA43DF8B55D" xlink:to="loc_us-gaap_HedgingDesignationAxis_A46A13B33348215BF2396DA43DF9E0AD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="loc_us-gaap_HedgingDesignationDomain_8D791B6B5AD2237BFBBA6DA43DF99C0B_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_HedgingDesignationAxis_A46A13B33348215BF2396DA43DF9E0AD" xlink:to="loc_us-gaap_HedgingDesignationDomain_8D791B6B5AD2237BFBBA6DA43DF99C0B_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="loc_us-gaap_HedgingDesignationDomain_8D791B6B5AD2237BFBBA6DA43DF99C0B" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_HedgingDesignationAxis_A46A13B33348215BF2396DA43DF9E0AD" xlink:to="loc_us-gaap_HedgingDesignationDomain_8D791B6B5AD2237BFBBA6DA43DF99C0B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DesignatedAsHedgingInstrumentMember" xlink:label="loc_us-gaap_DesignatedAsHedgingInstrumentMember_7665E119F58EA5987DF06DA43DF96533" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_8D791B6B5AD2237BFBBA6DA43DF99C0B" xlink:to="loc_us-gaap_DesignatedAsHedgingInstrumentMember_7665E119F58EA5987DF06DA43DF96533" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NondesignatedMember" xlink:label="loc_us-gaap_NondesignatedMember_77710949742E71C589FB6DA43DF9DB28" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_8D791B6B5AD2237BFBBA6DA43DF99C0B" xlink:to="loc_us-gaap_NondesignatedMember_77710949742E71C589FB6DA43DF9DB28" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_CC865D82DDF52E8B774A6DA43DF9F945" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_12BDBE6FB3816CF6F1536DA43DF8B55D" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_CC865D82DDF52E8B774A6DA43DF9F945" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_287245FB62FDF8B535AD6DA43DF9572D_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_CC865D82DDF52E8B774A6DA43DF9F945" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_287245FB62FDF8B535AD6DA43DF9572D_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_287245FB62FDF8B535AD6DA43DF9572D" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_CC865D82DDF52E8B774A6DA43DF9F945" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_287245FB62FDF8B535AD6DA43DF9572D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ForeignExchangeContractMember" xlink:label="loc_us-gaap_ForeignExchangeContractMember_8494CC56E6674DD39E016DA43DF93BDE" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_287245FB62FDF8B535AD6DA43DF9572D" xlink:to="loc_us-gaap_ForeignExchangeContractMember_8494CC56E6674DD39E016DA43DF93BDE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestRateContractMember" xlink:label="loc_us-gaap_InterestRateContractMember_72BAA3C23EDEA84369016DA43DF92B0B" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_287245FB62FDF8B535AD6DA43DF9572D" xlink:to="loc_us-gaap_InterestRateContractMember_72BAA3C23EDEA84369016DA43DF92B0B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetsFairValueDisclosureAbstract" xlink:label="loc_us-gaap_AssetsFairValueDisclosureAbstract_7491D8A9EA1CB40F89E96DA43E26F5F1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_2B614B749330D4595FC16DA43DF9D946" xlink:to="loc_us-gaap_AssetsFairValueDisclosureAbstract_7491D8A9EA1CB40F89E96DA43E26F5F1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeAssets" xlink:label="loc_us-gaap_DerivativeAssets_74BD0FA3ABD3CFCC55FE6DA43E267BAF" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_7491D8A9EA1CB40F89E96DA43E26F5F1" xlink:to="loc_us-gaap_DerivativeAssets_74BD0FA3ABD3CFCC55FE6DA43E267BAF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetsFairValueDisclosure" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_0E8984931E295F4829646DA43E2696E7" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_7491D8A9EA1CB40F89E96DA43E26F5F1" xlink:to="loc_us-gaap_AssetsFairValueDisclosure_0E8984931E295F4829646DA43E2696E7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract" xlink:label="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_AE99FDF7434C8006952B6DA43E26B6FB" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_2B614B749330D4595FC16DA43DF9D946" xlink:to="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_AE99FDF7434C8006952B6DA43E26B6FB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeLiabilities" xlink:label="loc_us-gaap_DerivativeLiabilities_8871318916EDA7E188756DA43E26BA43" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_AE99FDF7434C8006952B6DA43E26B6FB" xlink:to="loc_us-gaap_DerivativeLiabilities_8871318916EDA7E188756DA43E26BA43" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccruedLiabilitiesFairValueDisclosure" xlink:label="loc_us-gaap_AccruedLiabilitiesFairValueDisclosure_9801DC8FC43FED559C1D6DA43E27CE26" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_AE99FDF7434C8006952B6DA43E26B6FB" xlink:to="loc_us-gaap_AccruedLiabilitiesFairValueDisclosure_9801DC8FC43FED559C1D6DA43E27CE26" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosure" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosure_2F2E7DFAB2EFD20069C36DA43E271487" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_AE99FDF7434C8006952B6DA43E26B6FB" xlink:to="loc_us-gaap_LiabilitiesFairValueDisclosure_2F2E7DFAB2EFD20069C36DA43E271487" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/FairValueMeasurementsTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/FinancingArrangements" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/FinancingArrangementsLongTermDebtOutstandingRevolvingCreditAndEuropeanInvestmentBankFinancingAgreementDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="loc_us-gaap_DebtInstrumentLineItems_79B7CE140A4248BCB8927D2BD13D2E67" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="loc_us-gaap_DebtInstrumentTable_FCA58D1BEC6C06B8468D7D2BD13B72FE" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DebtInstrumentLineItems_79B7CE140A4248BCB8927D2BD13D2E67" xlink:to="loc_us-gaap_DebtInstrumentTable_FCA58D1BEC6C06B8468D7D2BD13B72FE" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_CFC6978C9AB2CD1255C47D2BD13CA150" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_FCA58D1BEC6C06B8468D7D2BD13B72FE" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_CFC6978C9AB2CD1255C47D2BD13CA150" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_08CB8E753311E248BDF37D2BD13C5F8C_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_CFC6978C9AB2CD1255C47D2BD13CA150" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_08CB8E753311E248BDF37D2BD13C5F8C_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_08CB8E753311E248BDF37D2BD13C5F8C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_CFC6978C9AB2CD1255C47D2BD13CA150" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_08CB8E753311E248BDF37D2BD13C5F8C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LoansPayableMember" xlink:label="loc_us-gaap_LoansPayableMember_AEE75832AC611958D2E77D2BD13C752B" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_08CB8E753311E248BDF37D2BD13C5F8C" xlink:to="loc_us-gaap_LoansPayableMember_AEE75832AC611958D2E77D2BD13C752B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MortgagesMember" xlink:label="loc_us-gaap_MortgagesMember_0B03F3F633F847FDA3367D2BD13CAB5F" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_08CB8E753311E248BDF37D2BD13C5F8C" xlink:to="loc_us-gaap_MortgagesMember_0B03F3F633F847FDA3367D2BD13CAB5F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LineOfCreditFacilityAxis" xlink:label="loc_us-gaap_LineOfCreditFacilityAxis_B6286224BDF3243C7BBD7D2BD13C1A11" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_FCA58D1BEC6C06B8468D7D2BD13B72FE" xlink:to="loc_us-gaap_LineOfCreditFacilityAxis_B6286224BDF3243C7BBD7D2BD13C1A11" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LineOfCreditFacilityLenderDomain" xlink:label="loc_us-gaap_LineOfCreditFacilityLenderDomain_337EB689101C1789D3577D2BD13C0328_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LineOfCreditFacilityAxis_B6286224BDF3243C7BBD7D2BD13C1A11" xlink:to="loc_us-gaap_LineOfCreditFacilityLenderDomain_337EB689101C1789D3577D2BD13C0328_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LineOfCreditFacilityLenderDomain" xlink:label="loc_us-gaap_LineOfCreditFacilityLenderDomain_337EB689101C1789D3577D2BD13C0328" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LineOfCreditFacilityAxis_B6286224BDF3243C7BBD7D2BD13C1A11" xlink:to="loc_us-gaap_LineOfCreditFacilityLenderDomain_337EB689101C1789D3577D2BD13C0328" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_EuropeanInvestmentBankMember" xlink:label="loc_livn_EuropeanInvestmentBankMember_3603E4E8695A865D337F7D2BD13CAFC0" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_337EB689101C1789D3577D2BD13C0328" xlink:to="loc_livn_EuropeanInvestmentBankMember_3603E4E8695A865D337F7D2BD13CAFC0" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_MediocreditoItalianoMember" xlink:label="loc_livn_MediocreditoItalianoMember_F6E351556316D367F25E7D2BD13D1BDE" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_337EB689101C1789D3577D2BD13C0328" xlink:to="loc_livn_MediocreditoItalianoMember_F6E351556316D367F25E7D2BD13D1BDE" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_BancadelMezzogiornoMember" xlink:label="loc_livn_BancadelMezzogiornoMember_278D6F33AC48D46AC07E7D2BD13DD5EA" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_337EB689101C1789D3577D2BD13C0328" xlink:to="loc_livn_BancadelMezzogiornoMember_278D6F33AC48D46AC07E7D2BD13DD5EA" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_BpifranceMember" xlink:label="loc_livn_BpifranceMember_85E1DB6F771ACC73C5297D2BD13D04E8" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_337EB689101C1789D3577D2BD13C0328" xlink:to="loc_livn_BpifranceMember_85E1DB6F771ACC73C5297D2BD13D04E8" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_NovaliaSAMember" xlink:label="loc_livn_NovaliaSAMember_261264D493BB386CB2867D2BD13D2FCA" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_337EB689101C1789D3577D2BD13C0328" xlink:to="loc_livn_NovaliaSAMember_261264D493BB386CB2867D2BD13D2FCA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CreditFacilityAxis" xlink:label="loc_us-gaap_CreditFacilityAxis_756D076C569986A9BC677D2BD13DE89E" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_FCA58D1BEC6C06B8468D7D2BD13B72FE" xlink:to="loc_us-gaap_CreditFacilityAxis_756D076C569986A9BC677D2BD13DE89E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="loc_us-gaap_CreditFacilityDomain_F435A64AAFD4C4EA3FD17D2BD13DCF5F_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_CreditFacilityAxis_756D076C569986A9BC677D2BD13DE89E" xlink:to="loc_us-gaap_CreditFacilityDomain_F435A64AAFD4C4EA3FD17D2BD13DCF5F_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="loc_us-gaap_CreditFacilityDomain_F435A64AAFD4C4EA3FD17D2BD13DCF5F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_CreditFacilityAxis_756D076C569986A9BC677D2BD13DE89E" xlink:to="loc_us-gaap_CreditFacilityDomain_F435A64AAFD4C4EA3FD17D2BD13DCF5F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RevolvingCreditFacilityMember" xlink:label="loc_us-gaap_RevolvingCreditFacilityMember_3B35365924660C50B66E7D2BD13DF519" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CreditFacilityDomain_F435A64AAFD4C4EA3FD17D2BD13DCF5F" xlink:to="loc_us-gaap_RevolvingCreditFacilityMember_3B35365924660C50B66E7D2BD13DF519" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentAxis" xlink:label="loc_us-gaap_DebtInstrumentAxis_8A0EAD04EB2017AC9BB87D2BD13D7970" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_FCA58D1BEC6C06B8468D7D2BD13B72FE" xlink:to="loc_us-gaap_DebtInstrumentAxis_8A0EAD04EB2017AC9BB87D2BD13D7970" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_8D2683283543D4DB60FC7D2BD13D9D6E_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DebtInstrumentAxis_8A0EAD04EB2017AC9BB87D2BD13D7970" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_8D2683283543D4DB60FC7D2BD13D9D6E_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentNameDomain" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_8D2683283543D4DB60FC7D2BD13D9D6E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DebtInstrumentAxis_8A0EAD04EB2017AC9BB87D2BD13D7970" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_8D2683283543D4DB60FC7D2BD13D9D6E" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_TrancheOneMember" xlink:label="loc_livn_TrancheOneMember_C1FD89D82948F43E41787D2BD13DF6B6" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_8D2683283543D4DB60FC7D2BD13D9D6E" xlink:to="loc_livn_TrancheOneMember_C1FD89D82948F43E41787D2BD13DF6B6" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_TrancheTwoMember" xlink:label="loc_livn_TrancheTwoMember_A9568BAF216284869BC67D2BD13DBACB" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_8D2683283543D4DB60FC7D2BD13D9D6E" xlink:to="loc_livn_TrancheTwoMember_A9568BAF216284869BC67D2BD13DBACB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RangeAxis" xlink:label="loc_us-gaap_RangeAxis_06BECABE9BBF3567B5467D2BD13DCF57" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_FCA58D1BEC6C06B8468D7D2BD13B72FE" xlink:to="loc_us-gaap_RangeAxis_06BECABE9BBF3567B5467D2BD13DCF57" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_84FAE6515846A04D85AE7D2BD13DD541_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RangeAxis_06BECABE9BBF3567B5467D2BD13DCF57" xlink:to="loc_us-gaap_RangeMember_84FAE6515846A04D85AE7D2BD13DD541_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RangeMember" xlink:label="loc_us-gaap_RangeMember_84FAE6515846A04D85AE7D2BD13DD541" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RangeAxis_06BECABE9BBF3567B5467D2BD13DCF57" xlink:to="loc_us-gaap_RangeMember_84FAE6515846A04D85AE7D2BD13DD541" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MinimumMember" xlink:label="loc_us-gaap_MinimumMember_7A0CFC5C6CAF33D41CE77D2BD13D6D97" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RangeMember_84FAE6515846A04D85AE7D2BD13DD541" xlink:to="loc_us-gaap_MinimumMember_7A0CFC5C6CAF33D41CE77D2BD13D6D97" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MaximumMember" xlink:label="loc_us-gaap_MaximumMember_601026505F2154DDA5157D2BD13D38DB" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RangeMember_84FAE6515846A04D85AE7D2BD13DD541" xlink:to="loc_us-gaap_MaximumMember_601026505F2154DDA5157D2BD13D38DB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentCarryingAmount" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_0A87449C491733E571947D2BD13DF0B2" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_79B7CE140A4248BCB8927D2BD13D2E67" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_0A87449C491733E571947D2BD13DF0B2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongTermDebtCurrent" xlink:label="loc_us-gaap_LongTermDebtCurrent_D958C0E9E3F9D4C874177D2BD1432CE6" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_79B7CE140A4248BCB8927D2BD13D2E67" xlink:to="loc_us-gaap_LongTermDebtCurrent_D958C0E9E3F9D4C874177D2BD1432CE6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongTermDebtNoncurrent" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_F66E8443CF4B21F7993A7D2BD1433960" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_79B7CE140A4248BCB8927D2BD13D2E67" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_F66E8443CF4B21F7993A7D2BD1433960" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShortTermBorrowings" xlink:label="loc_us-gaap_ShortTermBorrowings_8AD3B6DF1C96B2D347C07D2BD143F2EA" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_79B7CE140A4248BCB8927D2BD13D2E67" xlink:to="loc_us-gaap_ShortTermBorrowings_8AD3B6DF1C96B2D347C07D2BD143F2EA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage" xlink:label="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_961F453C6AD9219751C67D2BD1435D37" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_79B7CE140A4248BCB8927D2BD13D2E67" xlink:to="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_961F453C6AD9219751C67D2BD1435D37" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity" xlink:label="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_7A30D2D642DCF8007AB17D2BD1438C81" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_79B7CE140A4248BCB8927D2BD13D2E67" xlink:to="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_7A30D2D642DCF8007AB17D2BD1438C81" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProceedsFromLoans" xlink:label="loc_us-gaap_ProceedsFromLoans_75248ADF618C1FCA884C7D2BD143F9B7" xlink:type="locator" />
    <link:definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_79B7CE140A4248BCB8927D2BD13D2E67" xlink:to="loc_us-gaap_ProceedsFromLoans_75248ADF618C1FCA884C7D2BD143F9B7" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/FinancingArrangementsTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformation" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformationChangesInCarryingAmountOfGoodwillDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_3ADCDA2CE83AC718CD3C2FE5D1E698D7" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_B58B19EDA89E19BC28E52FE5D1E6B6B5" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_3ADCDA2CE83AC718CD3C2FE5D1E698D7" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_B58B19EDA89E19BC28E52FE5D1E6B6B5" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ConsolidationItemsAxis" xlink:label="loc_us-gaap_ConsolidationItemsAxis_0639ECF59EE6A372FFD12FE5D1E69C49" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_B58B19EDA89E19BC28E52FE5D1E6B6B5" xlink:to="loc_us-gaap_ConsolidationItemsAxis_0639ECF59EE6A372FFD12FE5D1E69C49" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ConsolidationItemsDomain" xlink:label="loc_us-gaap_ConsolidationItemsDomain_BC70F8E286060D32CCF02FE5D1E6B666_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ConsolidationItemsAxis_0639ECF59EE6A372FFD12FE5D1E69C49" xlink:to="loc_us-gaap_ConsolidationItemsDomain_BC70F8E286060D32CCF02FE5D1E6B666_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ConsolidationItemsDomain" xlink:label="loc_us-gaap_ConsolidationItemsDomain_BC70F8E286060D32CCF02FE5D1E6B666" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ConsolidationItemsAxis_0639ECF59EE6A372FFD12FE5D1E69C49" xlink:to="loc_us-gaap_ConsolidationItemsDomain_BC70F8E286060D32CCF02FE5D1E6B666" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingSegmentsMember" xlink:label="loc_us-gaap_OperatingSegmentsMember_5394546AC96D04406EA82FE5D1E6D623" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ConsolidationItemsDomain_BC70F8E286060D32CCF02FE5D1E6B666" xlink:to="loc_us-gaap_OperatingSegmentsMember_5394546AC96D04406EA82FE5D1E6D623" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CorporateNonSegmentMember" xlink:label="loc_us-gaap_CorporateNonSegmentMember_D3A3DC6B9341A035355B2FE5D1E6A257" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ConsolidationItemsDomain_BC70F8E286060D32CCF02FE5D1E6B666" xlink:to="loc_us-gaap_CorporateNonSegmentMember_D3A3DC6B9341A035355B2FE5D1E6A257" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_9AA81A6731B417C36BAB2FE5D1E63E70" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_B58B19EDA89E19BC28E52FE5D1E6B6B5" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_9AA81A6731B417C36BAB2FE5D1E63E70" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_1F28156635C0E6E9739C2FE5D1E66329_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_9AA81A6731B417C36BAB2FE5D1E63E70" xlink:to="loc_us-gaap_SegmentDomain_1F28156635C0E6E9739C2FE5D1E66329_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_1F28156635C0E6E9739C2FE5D1E66329" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_9AA81A6731B417C36BAB2FE5D1E63E70" xlink:to="loc_us-gaap_SegmentDomain_1F28156635C0E6E9739C2FE5D1E66329" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_NeuromodulationMember" xlink:label="loc_livn_NeuromodulationMember_06806D59BBE98C0C713F2FE5D1E6B555" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_1F28156635C0E6E9739C2FE5D1E66329" xlink:to="loc_livn_NeuromodulationMember_06806D59BBE98C0C713F2FE5D1E6B555" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_CardiacSurgeryMember" xlink:label="loc_livn_CardiacSurgeryMember_DDF0302C645DA557B7902FE5D1E6952D" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_1F28156635C0E6E9739C2FE5D1E66329" xlink:to="loc_livn_CardiacSurgeryMember_DDF0302C645DA557B7902FE5D1E6952D" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_CardiacRhythmManagementMember" xlink:label="loc_livn_CardiacRhythmManagementMember_CA7417BA544649E347D52FE5D1E6FD86" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_1F28156635C0E6E9739C2FE5D1E66329" xlink:to="loc_livn_CardiacRhythmManagementMember_CA7417BA544649E347D52FE5D1E6FD86" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillRollForward" xlink:label="loc_us-gaap_GoodwillRollForward_87CFCD29FF854E39A6162FE5D1E72F4A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_3ADCDA2CE83AC718CD3C2FE5D1E698D7" xlink:to="loc_us-gaap_GoodwillRollForward_87CFCD29FF854E39A6162FE5D1E72F4A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_A8091A1271EC9E076D0A2FE5D1E7978D" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillRollForward_87CFCD29FF854E39A6162FE5D1E72F4A" xlink:to="loc_us-gaap_Goodwill_A8091A1271EC9E076D0A2FE5D1E7978D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillAcquiredDuringPeriod" xlink:label="loc_us-gaap_GoodwillAcquiredDuringPeriod_C01BD684061A0F4E6E1B2FE5D1E76820" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillRollForward_87CFCD29FF854E39A6162FE5D1E72F4A" xlink:to="loc_us-gaap_GoodwillAcquiredDuringPeriod_C01BD684061A0F4E6E1B2FE5D1E76820" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GoodwillTranslationAndPurchaseAccountingAdjustments" xlink:label="loc_us-gaap_GoodwillTranslationAndPurchaseAccountingAdjustments_F70EE614CDED5B4573F02FE5D1E7052C" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillRollForward_87CFCD29FF854E39A6162FE5D1E72F4A" xlink:to="loc_us-gaap_GoodwillTranslationAndPurchaseAccountingAdjustments_F70EE614CDED5B4573F02FE5D1E7052C" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformationGeographicAreasDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems" xlink:label="loc_us-gaap_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems_56A4ADCD3B9F4DF9AAD84AD55AE2A286" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable" xlink:label="loc_us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable_F158B6E44619D39F42924AD55AE013BC" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems_56A4ADCD3B9F4DF9AAD84AD55AE2A286" xlink:to="loc_us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable_F158B6E44619D39F42924AD55AE013BC" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementGeographicalAxis" xlink:label="loc_us-gaap_StatementGeographicalAxis_1E6019391CEB4B57F5A84AD55AE11A01" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable_F158B6E44619D39F42924AD55AE013BC" xlink:to="loc_us-gaap_StatementGeographicalAxis_1E6019391CEB4B57F5A84AD55AE11A01" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentGeographicalDomain" xlink:label="loc_us-gaap_SegmentGeographicalDomain_46F8B39A3A830997FE534AD55AE109C7_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementGeographicalAxis_1E6019391CEB4B57F5A84AD55AE11A01" xlink:to="loc_us-gaap_SegmentGeographicalDomain_46F8B39A3A830997FE534AD55AE109C7_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentGeographicalDomain" xlink:label="loc_us-gaap_SegmentGeographicalDomain_46F8B39A3A830997FE534AD55AE109C7" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementGeographicalAxis_1E6019391CEB4B57F5A84AD55AE11A01" xlink:to="loc_us-gaap_SegmentGeographicalDomain_46F8B39A3A830997FE534AD55AE109C7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/country/2017/country-2017-01-31.xsd#country_US" xlink:label="loc_country_US_BE441190F242B388D44A4AD55AE1F73E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentGeographicalDomain_46F8B39A3A830997FE534AD55AE109C7" xlink:to="loc_country_US_BE441190F242B388D44A4AD55AE1F73E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EuropeMember" xlink:label="loc_us-gaap_EuropeMember_F32D17DB2A5F4822FB5B4AD55AE19A08" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentGeographicalDomain_46F8B39A3A830997FE534AD55AE109C7" xlink:to="loc_us-gaap_EuropeMember_F32D17DB2A5F4822FB5B4AD55AE19A08" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/country/2017/country-2017-01-31.xsd#country_GB" xlink:label="loc_country_GB_BCA367E0C5F476DEAA6B4AD55AE26029" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EuropeMember_F32D17DB2A5F4822FB5B4AD55AE19A08" xlink:to="loc_country_GB_BCA367E0C5F476DEAA6B4AD55AE26029" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/country/2017/country-2017-01-31.xsd#country_FR" xlink:label="loc_country_FR_0C1E417790D04F015B8C4AD55AE2DC03" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EuropeMember_F32D17DB2A5F4822FB5B4AD55AE19A08" xlink:to="loc_country_FR_0C1E417790D04F015B8C4AD55AE2DC03" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_NonU.S.andEuropeMember" xlink:label="loc_livn_NonU.S.andEuropeMember_B176C7F320E45304D02C4AD55AE279D5" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentGeographicalDomain_46F8B39A3A830997FE534AD55AE109C7" xlink:to="loc_livn_NonU.S.andEuropeMember_B176C7F320E45304D02C4AD55AE279D5" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_NumberofGeographicRegionsinwhichEntityOperates" xlink:label="loc_livn_NumberofGeographicRegionsinwhichEntityOperates_2F2C47C9B4A70487B26C4AD55AE274BA" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems_56A4ADCD3B9F4DF9AAD84AD55AE2A286" xlink:to="loc_livn_NumberofGeographicRegionsinwhichEntityOperates_2F2C47C9B4A70487B26C4AD55AE274BA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SalesRevenueNet" xlink:label="loc_us-gaap_SalesRevenueNet_A18EC4FD6DF244142EE14AD55AE26555" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems_56A4ADCD3B9F4DF9AAD84AD55AE2A286" xlink:to="loc_us-gaap_SalesRevenueNet_A18EC4FD6DF244142EE14AD55AE26555" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_BE935730D6FF17A6A0784AD55AE25C5D" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems_56A4ADCD3B9F4DF9AAD84AD55AE2A286" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_BE935730D6FF17A6A0784AD55AE25C5D" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformationSegmentInfoDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_2BC10E9073FB43D367750288F9030A22" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_45DEFA8842BE55E982BA0288F9022031" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_2BC10E9073FB43D367750288F9030A22" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_45DEFA8842BE55E982BA0288F9022031" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ConsolidationItemsAxis" xlink:label="loc_us-gaap_ConsolidationItemsAxis_4F6053D51DBF40B5E15A0288F902147B" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_45DEFA8842BE55E982BA0288F9022031" xlink:to="loc_us-gaap_ConsolidationItemsAxis_4F6053D51DBF40B5E15A0288F902147B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ConsolidationItemsDomain" xlink:label="loc_us-gaap_ConsolidationItemsDomain_8B86359B479F29F3D2DB0288F902E6D2_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ConsolidationItemsAxis_4F6053D51DBF40B5E15A0288F902147B" xlink:to="loc_us-gaap_ConsolidationItemsDomain_8B86359B479F29F3D2DB0288F902E6D2_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ConsolidationItemsDomain" xlink:label="loc_us-gaap_ConsolidationItemsDomain_8B86359B479F29F3D2DB0288F902E6D2" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ConsolidationItemsAxis_4F6053D51DBF40B5E15A0288F902147B" xlink:to="loc_us-gaap_ConsolidationItemsDomain_8B86359B479F29F3D2DB0288F902E6D2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingSegmentsMember" xlink:label="loc_us-gaap_OperatingSegmentsMember_05C1356300D7AA05BB460288F9027618" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ConsolidationItemsDomain_8B86359B479F29F3D2DB0288F902E6D2" xlink:to="loc_us-gaap_OperatingSegmentsMember_05C1356300D7AA05BB460288F9027618" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CorporateNonSegmentMember" xlink:label="loc_us-gaap_CorporateNonSegmentMember_C953A1E519A05C173BD50288F9022B20" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ConsolidationItemsDomain_8B86359B479F29F3D2DB0288F902E6D2" xlink:to="loc_us-gaap_CorporateNonSegmentMember_C953A1E519A05C173BD50288F9022B20" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_AF63861B3D2986DA91F50288F90239BB" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_45DEFA8842BE55E982BA0288F9022031" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_AF63861B3D2986DA91F50288F90239BB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_F5AE4244F817EDC2E31E0288F902AFA0_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_AF63861B3D2986DA91F50288F90239BB" xlink:to="loc_us-gaap_SegmentDomain_F5AE4244F817EDC2E31E0288F902AFA0_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_F5AE4244F817EDC2E31E0288F902AFA0" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_AF63861B3D2986DA91F50288F90239BB" xlink:to="loc_us-gaap_SegmentDomain_F5AE4244F817EDC2E31E0288F902AFA0" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_CardiacSurgeryMember" xlink:label="loc_livn_CardiacSurgeryMember_7B0ACD917B96CF79AE160288F902F26D" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_F5AE4244F817EDC2E31E0288F902AFA0" xlink:to="loc_livn_CardiacSurgeryMember_7B0ACD917B96CF79AE160288F902F26D" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_NeuromodulationMember" xlink:label="loc_livn_NeuromodulationMember_9307EA420DD70AA4861B0288F90252BB" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_F5AE4244F817EDC2E31E0288F902AFA0" xlink:to="loc_livn_NeuromodulationMember_9307EA420DD70AA4861B0288F90252BB" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_CardiacRhythmManagementMember" xlink:label="loc_livn_CardiacRhythmManagementMember_C0CC0887088913698BB40288F9032D29" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_F5AE4244F817EDC2E31E0288F902AFA0" xlink:to="loc_livn_CardiacRhythmManagementMember_C0CC0887088913698BB40288F9032D29" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SalesRevenueNet" xlink:label="loc_us-gaap_SalesRevenueNet_81D414EA37BE33F8CFE60288F903CCB5" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_2BC10E9073FB43D367750288F9030A22" xlink:to="loc_us-gaap_SalesRevenueNet_81D414EA37BE33F8CFE60288F903CCB5" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_IncomeLossfromReportableSegmentsbeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:label="loc_livn_IncomeLossfromReportableSegmentsbeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_DEE210FEEC99FDEE57A50288F90377AC" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_2BC10E9073FB43D367750288F9030A22" xlink:to="loc_livn_IncomeLossfromReportableSegmentsbeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_DEE210FEEC99FDEE57A50288F90377AC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationIntegrationRelatedCosts" xlink:label="loc_us-gaap_BusinessCombinationIntegrationRelatedCosts_2F8116F7F9A0546FBD660288F903F4C0" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_2BC10E9073FB43D367750288F9030A22" xlink:to="loc_us-gaap_BusinessCombinationIntegrationRelatedCosts_2F8116F7F9A0546FBD660288F903F4C0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_BD854CE29AE6819249340288F903DFBB" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_2BC10E9073FB43D367750288F9030A22" xlink:to="loc_us-gaap_RestructuringCharges_BD854CE29AE6819249340288F903DFBB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_4D46F5BAAADF14AA776F0288F9030A48" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_2BC10E9073FB43D367750288F9030A22" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_4D46F5BAAADF14AA776F0288F9030A48" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaap_OperatingIncomeLoss_9D2B072E06BA2B8DB94B0288F903C1D7" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_2BC10E9073FB43D367750288F9030A22" xlink:to="loc_us-gaap_OperatingIncomeLoss_9D2B072E06BA2B8DB94B0288F903C1D7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Assets" xlink:label="loc_us-gaap_Assets_5665643E4518A179E9B50288F903E03A" xlink:type="locator" />
    <link:definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_2BC10E9073FB43D367750288F9030A22" xlink:to="loc_us-gaap_Assets_5665643E4518A179E9B50288F903E03A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PropertyPlantAndEquipmentAdditions" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAdditions_2DC725F41A598A00F5DD0288F90328FA" xlink:type="locator" />
    <link:definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_2BC10E9073FB43D367750288F9030A22" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentAdditions_2DC725F41A598A00F5DD0288F90328FA" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformationTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/IncomeTaxes" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/IncomeTaxesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxContingencyLineItems" xlink:label="loc_us-gaap_IncomeTaxContingencyLineItems_9C2E14A03FE033FFE90379101CCD8BE8" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxContingencyTable" xlink:label="loc_us-gaap_IncomeTaxContingencyTable_A712640A74B2C92A9DD679101CCCEF52" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_IncomeTaxContingencyLineItems_9C2E14A03FE033FFE90379101CCD8BE8" xlink:to="loc_us-gaap_IncomeTaxContingencyTable_A712640A74B2C92A9DD679101CCCEF52" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxAuthorityNameAxis" xlink:label="loc_us-gaap_IncomeTaxAuthorityNameAxis_EDD8517E2CBCD3C2B1F179101CCC8164" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_IncomeTaxContingencyTable_A712640A74B2C92A9DD679101CCCEF52" xlink:to="loc_us-gaap_IncomeTaxAuthorityNameAxis_EDD8517E2CBCD3C2B1F179101CCC8164" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxAuthorityNameDomain" xlink:label="loc_us-gaap_IncomeTaxAuthorityNameDomain_D52AD2FD36DCFF387FF179101CCC35E4_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeTaxAuthorityNameAxis_EDD8517E2CBCD3C2B1F179101CCC8164" xlink:to="loc_us-gaap_IncomeTaxAuthorityNameDomain_D52AD2FD36DCFF387FF179101CCC35E4_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxAuthorityNameDomain" xlink:label="loc_us-gaap_IncomeTaxAuthorityNameDomain_D52AD2FD36DCFF387FF179101CCC35E4" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeTaxAuthorityNameAxis_EDD8517E2CBCD3C2B1F179101CCC8164" xlink:to="loc_us-gaap_IncomeTaxAuthorityNameDomain_D52AD2FD36DCFF387FF179101CCC35E4" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_HerMajestysRevenueandCustomsHMRCandMinistryoftheEconomyFinanceandIndustryFranceMember" xlink:label="loc_livn_HerMajestysRevenueandCustomsHMRCandMinistryoftheEconomyFinanceandIndustryFranceMember_8A87CE2108F90265D85879101CCCC1CE" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxAuthorityNameDomain_D52AD2FD36DCFF387FF179101CCC35E4" xlink:to="loc_livn_HerMajestysRevenueandCustomsHMRCandMinistryoftheEconomyFinanceandIndustryFranceMember_8A87CE2108F90265D85879101CCCC1CE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxAuthorityAxis" xlink:label="loc_us-gaap_IncomeTaxAuthorityAxis_FD75C6B464B1DE4DD05479101CCCB686" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_IncomeTaxContingencyTable_A712640A74B2C92A9DD679101CCCEF52" xlink:to="loc_us-gaap_IncomeTaxAuthorityAxis_FD75C6B464B1DE4DD05479101CCCB686" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxAuthorityDomain" xlink:label="loc_us-gaap_IncomeTaxAuthorityDomain_E138EB8799D57A28DF1C79101CCCEFB3_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeTaxAuthorityAxis_FD75C6B464B1DE4DD05479101CCCB686" xlink:to="loc_us-gaap_IncomeTaxAuthorityDomain_E138EB8799D57A28DF1C79101CCCEFB3_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxAuthorityDomain" xlink:label="loc_us-gaap_IncomeTaxAuthorityDomain_E138EB8799D57A28DF1C79101CCCEFB3" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeTaxAuthorityAxis_FD75C6B464B1DE4DD05479101CCCB686" xlink:to="loc_us-gaap_IncomeTaxAuthorityDomain_E138EB8799D57A28DF1C79101CCCEFB3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ForeignCountryMember" xlink:label="loc_us-gaap_ForeignCountryMember_D2565A50B31A91ACD0F579101CCC1456" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxAuthorityDomain_E138EB8799D57A28DF1C79101CCCEFB3" xlink:to="loc_us-gaap_ForeignCountryMember_D2565A50B31A91ACD0F579101CCC1456" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_E32FB43B210BBE41143379101CCDAA23" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_IncomeTaxContingencyTable_A712640A74B2C92A9DD679101CCCEF52" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_E32FB43B210BBE41143379101CCDAA23" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_21D68A50A186505BEC6679101CCDF040_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_E32FB43B210BBE41143379101CCDAA23" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_21D68A50A186505BEC6679101CCDF040_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_21D68A50A186505BEC6679101CCDF040" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_E32FB43B210BBE41143379101CCDAA23" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_21D68A50A186505BEC6679101CCDF040" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_CaissonInterventionalLLCMember" xlink:label="loc_livn_CaissonInterventionalLLCMember_8F7E6187F972F9963B2F79101CCDA542" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_21D68A50A186505BEC6679101CCDF040" xlink:to="loc_livn_CaissonInterventionalLLCMember_8F7E6187F972F9963B2F79101CCDA542" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_BE62F62A36DCE9B8F31379101CCDAA39" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxContingencyLineItems_9C2E14A03FE033FFE90379101CCD8BE8" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_BE62F62A36DCE9B8F31379101CCDAA39" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EffectiveIncomeTaxRateContinuingOperations" xlink:label="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_66E10A6AE7BF6AA7BDB579101CCD6522" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxContingencyLineItems_9C2E14A03FE033FFE90379101CCD8BE8" xlink:to="loc_us-gaap_EffectiveIncomeTaxRateContinuingOperations_66E10A6AE7BF6AA7BDB579101CCD6522" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_EffectiveIncomeTaxRateReconciliationsDeferredTaxBenefitfromReleaseofValuationAllowancesonTaxLossesRelatedtoaReorganization" xlink:label="loc_livn_EffectiveIncomeTaxRateReconciliationsDeferredTaxBenefitfromReleaseofValuationAllowancesonTaxLossesRelatedtoaReorganization_701FE514533828D76B1679101CCD51CA" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxContingencyLineItems_9C2E14A03FE033FFE90379101CCD8BE8" xlink:to="loc_livn_EffectiveIncomeTaxRateReconciliationsDeferredTaxBenefitfromReleaseofValuationAllowancesonTaxLossesRelatedtoaReorganization_701FE514533828D76B1679101CCD51CA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxReconciliationTaxSettlements" xlink:label="loc_us-gaap_IncomeTaxReconciliationTaxSettlements_EF5647847640735154DC79101CCD3179" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxContingencyLineItems_9C2E14A03FE033FFE90379101CCD8BE8" xlink:to="loc_us-gaap_IncomeTaxReconciliationTaxSettlements_EF5647847640735154DC79101CCD3179" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_EffectiveIncomeTaxRateReconciliationFairValueAdjustmentofEquityMethodInvestmentAmount" xlink:label="loc_livn_EffectiveIncomeTaxRateReconciliationFairValueAdjustmentofEquityMethodInvestmentAmount_6808201793A8F76001A879101CCD4BE9" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxContingencyLineItems_9C2E14A03FE033FFE90379101CCD8BE8" xlink:to="loc_livn_EffectiveIncomeTaxRateReconciliationFairValueAdjustmentofEquityMethodInvestmentAmount_6808201793A8F76001A879101CCD4BE9" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_EffectiveIncomeTaxRateReconciliationDeferredTaxBenefitfromAcquisitionsAmount" xlink:label="loc_livn_EffectiveIncomeTaxRateReconciliationDeferredTaxBenefitfromAcquisitionsAmount_5204D61BD2EC161C34CE79101CCD3D27" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxContingencyLineItems_9C2E14A03FE033FFE90379101CCD8BE8" xlink:to="loc_livn_EffectiveIncomeTaxRateReconciliationDeferredTaxBenefitfromAcquisitionsAmount_5204D61BD2EC161C34CE79101CCD3D27" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_EffectiveIncomeTaxRateReconciliationDeferredTaxAssetPriorYearUncertainTaxPositionsAmount" xlink:label="loc_livn_EffectiveIncomeTaxRateReconciliationDeferredTaxAssetPriorYearUncertainTaxPositionsAmount_8B462F54F90939BBDAAC79101CCDE99C" xlink:type="locator" />
    <link:definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxContingencyLineItems_9C2E14A03FE033FFE90379101CCD8BE8" xlink:to="loc_livn_EffectiveIncomeTaxRateReconciliationDeferredTaxAssetPriorYearUncertainTaxPositionsAmount_8B462F54F90939BBDAAC79101CCDE99C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherTaxExpenseBenefit" xlink:label="loc_us-gaap_OtherTaxExpenseBenefit_8BF458AC5EA4FE69561079101CCD9591" xlink:type="locator" />
    <link:definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxContingencyLineItems_9C2E14A03FE033FFE90379101CCD8BE8" xlink:to="loc_us-gaap_OtherTaxExpenseBenefit_8BF458AC5EA4FE69561079101CCD9591" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount" xlink:label="loc_us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount_6B6835E26C767F8549C379101CCD06F4" xlink:type="locator" />
    <link:definitionArc order="9" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxContingencyLineItems_9C2E14A03FE033FFE90379101CCD8BE8" xlink:to="loc_us-gaap_ValuationAllowanceDeferredTaxAssetChangeInAmount_6B6835E26C767F8549C379101CCD06F4" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/Investments" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/InvestmentsCostMethodInvestmentsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfCostMethodInvestmentsLineItems" xlink:label="loc_us-gaap_ScheduleOfCostMethodInvestmentsLineItems_70CE0117CACB60E461B74B20EDDAFCE5" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfCostMethodInvestmentsTable" xlink:label="loc_us-gaap_ScheduleOfCostMethodInvestmentsTable_1AE3BE3BA04804B3A1944B20EDD9B5E1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ScheduleOfCostMethodInvestmentsLineItems_70CE0117CACB60E461B74B20EDDAFCE5" xlink:to="loc_us-gaap_ScheduleOfCostMethodInvestmentsTable_1AE3BE3BA04804B3A1944B20EDD9B5E1" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_CF22AC1847020B3BC3154B20EDD9A0D1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfCostMethodInvestmentsTable_1AE3BE3BA04804B3A1944B20EDD9B5E1" xlink:to="loc_us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_CF22AC1847020B3BC3154B20EDD9A0D1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquityMethodInvesteeNameDomain" xlink:label="loc_us-gaap_EquityMethodInvesteeNameDomain_6B7F96398992D2006E964B20EDD9D6D2_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_CF22AC1847020B3BC3154B20EDD9A0D1" xlink:to="loc_us-gaap_EquityMethodInvesteeNameDomain_6B7F96398992D2006E964B20EDD9D6D2_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquityMethodInvesteeNameDomain" xlink:label="loc_us-gaap_EquityMethodInvesteeNameDomain_6B7F96398992D2006E964B20EDD9D6D2" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_CF22AC1847020B3BC3154B20EDD9A0D1" xlink:to="loc_us-gaap_EquityMethodInvesteeNameDomain_6B7F96398992D2006E964B20EDD9D6D2" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_RespicardiaMember" xlink:label="loc_livn_RespicardiaMember_BCA36FA328A69E13964F4B20EDD939BB" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityMethodInvesteeNameDomain_6B7F96398992D2006E964B20EDD9D6D2" xlink:to="loc_livn_RespicardiaMember_BCA36FA328A69E13964F4B20EDD939BB" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_ImTheraMedicalInc.Member" xlink:label="loc_livn_ImTheraMedicalInc.Member_90999137B2DBA1F65A174B20EDD90096" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityMethodInvesteeNameDomain_6B7F96398992D2006E964B20EDD9D6D2" xlink:to="loc_livn_ImTheraMedicalInc.Member_90999137B2DBA1F65A174B20EDD90096" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_RainbowMedicalLtd.Member" xlink:label="loc_livn_RainbowMedicalLtd.Member_29CF12CA052A14FA1E4E4B20EDDAB594" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityMethodInvesteeNameDomain_6B7F96398992D2006E964B20EDD9D6D2" xlink:to="loc_livn_RainbowMedicalLtd.Member_29CF12CA052A14FA1E4E4B20EDDAB594" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_MDStartIIMember" xlink:label="loc_livn_MDStartIIMember_36763E9DB490304DFD6E4B20EDDABB36" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityMethodInvesteeNameDomain_6B7F96398992D2006E964B20EDD9D6D2" xlink:to="loc_livn_MDStartIIMember_36763E9DB490304DFD6E4B20EDDABB36" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_OtherMember" xlink:label="loc_livn_OtherMember_D287C105BA065795FE614B20EDDAFF7B" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityMethodInvesteeNameDomain_6B7F96398992D2006E964B20EDD9D6D2" xlink:to="loc_livn_OtherMember_D287C105BA065795FE614B20EDDAFF7B" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_IstitutoEuropeodiOncologiaS.R.L.Member" xlink:label="loc_livn_IstitutoEuropeodiOncologiaS.R.L.Member_1402C56D8EBBD15B79924B20EDDA47DD" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityMethodInvesteeNameDomain_6B7F96398992D2006E964B20EDD9D6D2" xlink:to="loc_livn_IstitutoEuropeodiOncologiaS.R.L.Member_1402C56D8EBBD15B79924B20EDDA47DD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RelatedPartyTransactionAxis" xlink:label="loc_us-gaap_RelatedPartyTransactionAxis_6A818A59E38A8946093A4B20EDDADD0C" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfCostMethodInvestmentsTable_1AE3BE3BA04804B3A1944B20EDD9B5E1" xlink:to="loc_us-gaap_RelatedPartyTransactionAxis_6A818A59E38A8946093A4B20EDDADD0C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RelatedPartyTransactionDomain" xlink:label="loc_us-gaap_RelatedPartyTransactionDomain_E5CC50AF21C8FBFE91034B20EDDA1AD1_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RelatedPartyTransactionAxis_6A818A59E38A8946093A4B20EDDADD0C" xlink:to="loc_us-gaap_RelatedPartyTransactionDomain_E5CC50AF21C8FBFE91034B20EDDA1AD1_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RelatedPartyTransactionDomain" xlink:label="loc_us-gaap_RelatedPartyTransactionDomain_E5CC50AF21C8FBFE91034B20EDDA1AD1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RelatedPartyTransactionAxis_6A818A59E38A8946093A4B20EDDADD0C" xlink:to="loc_us-gaap_RelatedPartyTransactionDomain_E5CC50AF21C8FBFE91034B20EDDA1AD1" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_CostMethodInvesteeMember" xlink:label="loc_livn_CostMethodInvesteeMember_E5B4CAAB38CD7D1A0CD34B20EDDAD650" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_E5CC50AF21C8FBFE91034B20EDDA1AD1" xlink:to="loc_livn_CostMethodInvesteeMember_E5B4CAAB38CD7D1A0CD34B20EDDAD650" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CounterpartyNameAxis" xlink:label="loc_us-gaap_CounterpartyNameAxis_62482611D80C082661954B20EDDA7A36" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfCostMethodInvestmentsTable_1AE3BE3BA04804B3A1944B20EDD9B5E1" xlink:to="loc_us-gaap_CounterpartyNameAxis_62482611D80C082661954B20EDDA7A36" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RepurchaseAgreementCounterpartyNameDomain" xlink:label="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_023BC1EFE8B2FA6A3A5E4B20EDDAF736_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_CounterpartyNameAxis_62482611D80C082661954B20EDDA7A36" xlink:to="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_023BC1EFE8B2FA6A3A5E4B20EDDAF736_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RepurchaseAgreementCounterpartyNameDomain" xlink:label="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_023BC1EFE8B2FA6A3A5E4B20EDDAF736" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_CounterpartyNameAxis_62482611D80C082661954B20EDDA7A36" xlink:to="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_023BC1EFE8B2FA6A3A5E4B20EDDAF736" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_RespicardiaMember" xlink:label="loc_livn_RespicardiaMember_96127439D6FB08ABD2354B20EDDAC0B9" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_023BC1EFE8B2FA6A3A5E4B20EDDAF736" xlink:to="loc_livn_RespicardiaMember_96127439D6FB08ABD2354B20EDDAC0B9" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_ImTheraMedicalInc.Member" xlink:label="loc_livn_ImTheraMedicalInc.Member_74CAC5329C69137227B84B20EDDAAEE8" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RepurchaseAgreementCounterpartyNameDomain_023BC1EFE8B2FA6A3A5E4B20EDDAF736" xlink:to="loc_livn_ImTheraMedicalInc.Member_74CAC5329C69137227B84B20EDDAAEE8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" xlink:label="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_F103F560B36DCACAD8BA4B20EDDAC3BD" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfCostMethodInvestmentsTable_1AE3BE3BA04804B3A1944B20EDD9B5E1" xlink:to="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_F103F560B36DCACAD8BA4B20EDDAC3BD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RelatedPartyDomain" xlink:label="loc_us-gaap_RelatedPartyDomain_B0866C2B9653DF6A313A4B20EDDA8BA5_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_F103F560B36DCACAD8BA4B20EDDAC3BD" xlink:to="loc_us-gaap_RelatedPartyDomain_B0866C2B9653DF6A313A4B20EDDA8BA5_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RelatedPartyDomain" xlink:label="loc_us-gaap_RelatedPartyDomain_B0866C2B9653DF6A313A4B20EDDA8BA5" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_F103F560B36DCACAD8BA4B20EDDAC3BD" xlink:to="loc_us-gaap_RelatedPartyDomain_B0866C2B9653DF6A313A4B20EDDA8BA5" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_CostMethodInvesteeMember" xlink:label="loc_livn_CostMethodInvesteeMember_C9276440EA0B2924AEBD4B20EDDAD712" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RelatedPartyDomain_B0866C2B9653DF6A313A4B20EDDA8BA5" xlink:to="loc_livn_CostMethodInvesteeMember_C9276440EA0B2924AEBD4B20EDDAD712" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BalanceSheetLocationAxis" xlink:label="loc_us-gaap_BalanceSheetLocationAxis_791C5A4A7E4E2AF10C264B20EDDAC710" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfCostMethodInvestmentsTable_1AE3BE3BA04804B3A1944B20EDD9B5E1" xlink:to="loc_us-gaap_BalanceSheetLocationAxis_791C5A4A7E4E2AF10C264B20EDDAC710" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BalanceSheetLocationDomain" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_4FAAF87BEF79E9CBFB394B20EDDA3776_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_791C5A4A7E4E2AF10C264B20EDDAC710" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_4FAAF87BEF79E9CBFB394B20EDDA3776_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BalanceSheetLocationDomain" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_4FAAF87BEF79E9CBFB394B20EDDA3776" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_791C5A4A7E4E2AF10C264B20EDDAC710" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_4FAAF87BEF79E9CBFB394B20EDDA3776" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherAssetsMember" xlink:label="loc_us-gaap_OtherAssetsMember_8AAEB5577DCB1B59580C4B20EDDA0727" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_4FAAF87BEF79E9CBFB394B20EDDA3776" xlink:to="loc_us-gaap_OtherAssetsMember_8AAEB5577DCB1B59580C4B20EDDA0727" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CostMethodInvestmentsOriginalCost" xlink:label="loc_us-gaap_CostMethodInvestmentsOriginalCost_E7DDC986389435C9FFF64B20EDDA9ECE" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfCostMethodInvestmentsLineItems_70CE0117CACB60E461B74B20EDDAFCE5" xlink:to="loc_us-gaap_CostMethodInvestmentsOriginalCost_E7DDC986389435C9FFF64B20EDDA9ECE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LoansAndLeasesReceivableRelatedParties" xlink:label="loc_us-gaap_LoansAndLeasesReceivableRelatedParties_1F442810060FD94EDC4C4B20EDDA9108" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfCostMethodInvestmentsLineItems_70CE0117CACB60E461B74B20EDDAFCE5" xlink:to="loc_us-gaap_LoansAndLeasesReceivableRelatedParties_1F442810060FD94EDC4C4B20EDDA9108" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_ForeignCurrencyTransactionGainLossandOtherNonoperatingIncome" xlink:label="loc_livn_ForeignCurrencyTransactionGainLossandOtherNonoperatingIncome_A3DDAABC5C21FBD486914B20EDDBEE1C" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfCostMethodInvestmentsLineItems_70CE0117CACB60E461B74B20EDDAFCE5" xlink:to="loc_livn_ForeignCurrencyTransactionGainLossandOtherNonoperatingIncome_A3DDAABC5C21FBD486914B20EDDBEE1C" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/InvestmentsEquityMethodInvestmentsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfEquityMethodInvestmentsLineItems" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_15CE5951D0D1A3E0D6365502E2C17933" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfEquityMethodInvestmentsTable" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_FCAB94EBB1509AF5A7D95502E2C05197" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_15CE5951D0D1A3E0D6365502E2C17933" xlink:to="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_FCAB94EBB1509AF5A7D95502E2C05197" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_137AAAFD82C3C65042585502E2C00F85" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_FCAB94EBB1509AF5A7D95502E2C05197" xlink:to="loc_us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_137AAAFD82C3C65042585502E2C00F85" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquityMethodInvesteeNameDomain" xlink:label="loc_us-gaap_EquityMethodInvesteeNameDomain_4B58F842351D191310AD5502E2C03A54_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_137AAAFD82C3C65042585502E2C00F85" xlink:to="loc_us-gaap_EquityMethodInvesteeNameDomain_4B58F842351D191310AD5502E2C03A54_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquityMethodInvesteeNameDomain" xlink:label="loc_us-gaap_EquityMethodInvesteeNameDomain_4B58F842351D191310AD5502E2C03A54" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_137AAAFD82C3C65042585502E2C00F85" xlink:to="loc_us-gaap_EquityMethodInvesteeNameDomain_4B58F842351D191310AD5502E2C03A54" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_MicroPortSorinCRMCoLtdMember" xlink:label="loc_livn_MicroPortSorinCRMCoLtdMember_EAB22438C20A91B1E53A5502E2C1A9DF" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityMethodInvesteeNameDomain_4B58F842351D191310AD5502E2C03A54" xlink:to="loc_livn_MicroPortSorinCRMCoLtdMember_EAB22438C20A91B1E53A5502E2C1A9DF" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_HighlifeS.A.S.Member" xlink:label="loc_livn_HighlifeS.A.S.Member_CCEFD99F564241D7222C5502E2C17763" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityMethodInvesteeNameDomain_4B58F842351D191310AD5502E2C03A54" xlink:to="loc_livn_HighlifeS.A.S.Member_CCEFD99F564241D7222C5502E2C17763" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_CaissonInterventionalLLCMember" xlink:label="loc_livn_CaissonInterventionalLLCMember_FE7AFD3F8E3F6AEAC83C5502E2C0E8B0" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityMethodInvesteeNameDomain_4B58F842351D191310AD5502E2C03A54" xlink:to="loc_livn_CaissonInterventionalLLCMember_FE7AFD3F8E3F6AEAC83C5502E2C0E8B0" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_OtherEquityMethodInvestmentsMember" xlink:label="loc_livn_OtherEquityMethodInvestmentsMember_C94323759407E329D8D95502E2C150A3" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityMethodInvesteeNameDomain_4B58F842351D191310AD5502E2C03A54" xlink:to="loc_livn_OtherEquityMethodInvestmentsMember_C94323759407E329D8D95502E2C150A3" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_CaissonInterventionalLLCandHighlifeS.A.S.Member" xlink:label="loc_livn_CaissonInterventionalLLCandHighlifeS.A.S.Member_27828E1E6415881C84E95502E2C19335" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityMethodInvesteeNameDomain_4B58F842351D191310AD5502E2C03A54" xlink:to="loc_livn_CaissonInterventionalLLCandHighlifeS.A.S.Member_27828E1E6415881C84E95502E2C19335" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_5FFFF936ECED09C16F1D5502E2C13543" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_FCAB94EBB1509AF5A7D95502E2C05197" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_5FFFF936ECED09C16F1D5502E2C13543" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_DB7AF17268A37ADE8B035502E2C1EE77_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_5FFFF936ECED09C16F1D5502E2C13543" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_DB7AF17268A37ADE8B035502E2C1EE77_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_DB7AF17268A37ADE8B035502E2C1EE77" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_5FFFF936ECED09C16F1D5502E2C13543" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_DB7AF17268A37ADE8B035502E2C1EE77" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_CaissonInterventionalLLCMember" xlink:label="loc_livn_CaissonInterventionalLLCMember_2AC04E40E9743BEA19A35502E2C10466" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_DB7AF17268A37ADE8B035502E2C1EE77" xlink:to="loc_livn_CaissonInterventionalLLCMember_2AC04E40E9743BEA19A35502E2C10466" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BalanceSheetLocationAxis" xlink:label="loc_us-gaap_BalanceSheetLocationAxis_2821BDFF1068E60BE20B5502E2C13FDD" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsTable_FCAB94EBB1509AF5A7D95502E2C05197" xlink:to="loc_us-gaap_BalanceSheetLocationAxis_2821BDFF1068E60BE20B5502E2C13FDD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BalanceSheetLocationDomain" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_72FFB2E8CF51249373535502E2C1E03F_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_2821BDFF1068E60BE20B5502E2C13FDD" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_72FFB2E8CF51249373535502E2C1E03F_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BalanceSheetLocationDomain" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_72FFB2E8CF51249373535502E2C1E03F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_2821BDFF1068E60BE20B5502E2C13FDD" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_72FFB2E8CF51249373535502E2C1E03F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherAssetsMember" xlink:label="loc_us-gaap_OtherAssetsMember_6E02F5A591AFDA2D116B5502E2C1267B" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_72FFB2E8CF51249373535502E2C1E03F" xlink:to="loc_us-gaap_OtherAssetsMember_6E02F5A591AFDA2D116B5502E2C1267B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquityMethodInvestmentOwnershipPercentage" xlink:label="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage_2977058DA4011AC8B8445502E2C18710" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_15CE5951D0D1A3E0D6365502E2C17933" xlink:to="loc_us-gaap_EquityMethodInvestmentOwnershipPercentage_2977058DA4011AC8B8445502E2C18710" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquityMethodInvestments" xlink:label="loc_us-gaap_EquityMethodInvestments_AEAE7E435CEECBA7B6DD5502E2C17020" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_15CE5951D0D1A3E0D6365502E2C17933" xlink:to="loc_us-gaap_EquityMethodInvestments_AEAE7E435CEECBA7B6DD5502E2C17020" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesAndInterestInAffiliates" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesAndInterestInAffiliates_8937B344AD9ADF1A998C55170180DF34" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_15CE5951D0D1A3E0D6365502E2C17933" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesAndInterestInAffiliates_8937B344AD9ADF1A998C55170180DF34" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_BusinessCombinationEquityInterestinAcquireePercentage" xlink:label="loc_livn_BusinessCombinationEquityInterestinAcquireePercentage_F61654515BC1342486525502E2C145E1" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_15CE5951D0D1A3E0D6365502E2C17933" xlink:to="loc_livn_BusinessCombinationEquityInterestinAcquireePercentage_F61654515BC1342486525502E2C145E1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ImpairmentOfInvestments" xlink:label="loc_us-gaap_ImpairmentOfInvestments_AA4EEF0F85E701FCD3F75502E2C1510E" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_15CE5951D0D1A3E0D6365502E2C17933" xlink:to="loc_us-gaap_ImpairmentOfInvestments_AA4EEF0F85E701FCD3F75502E2C1510E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LoansAndLeasesReceivableRelatedParties" xlink:label="loc_us-gaap_LoansAndLeasesReceivableRelatedParties_F691E8190D10AB4F019C5502E2C10F47" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_15CE5951D0D1A3E0D6365502E2C17933" xlink:to="loc_us-gaap_LoansAndLeasesReceivableRelatedParties_F691E8190D10AB4F019C5502E2C10F47" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/InvestmentsTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/NetIncomeLossPerShare" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/NetIncomeLossPerShareNarrativeOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_35E1911B36E47FEA9D792FE5D1F3F97C" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_F3B1FBA7CB2F16083B8F2FE5D1F3D89F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_35E1911B36E47FEA9D792FE5D1F3F97C" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_F3B1FBA7CB2F16083B8F2FE5D1F3D89F" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_70FAD0E68718A8F1CBE72FE5D1F3AA68" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_F3B1FBA7CB2F16083B8F2FE5D1F3D89F" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_70FAD0E68718A8F1CBE72FE5D1F3AA68" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AntidilutiveSecuritiesNameDomain" xlink:label="loc_us-gaap_AntidilutiveSecuritiesNameDomain_EF260ABED4C7002191D52FE5D1F3FD2D_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_70FAD0E68718A8F1CBE72FE5D1F3AA68" xlink:to="loc_us-gaap_AntidilutiveSecuritiesNameDomain_EF260ABED4C7002191D52FE5D1F3FD2D_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AntidilutiveSecuritiesNameDomain" xlink:label="loc_us-gaap_AntidilutiveSecuritiesNameDomain_EF260ABED4C7002191D52FE5D1F3FD2D" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_70FAD0E68718A8F1CBE72FE5D1F3AA68" xlink:to="loc_us-gaap_AntidilutiveSecuritiesNameDomain_EF260ABED4C7002191D52FE5D1F3FD2D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StockCompensationPlanMember" xlink:label="loc_us-gaap_StockCompensationPlanMember_80A30BF8BDE2E494EB6B2FE5D1F318BB" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_EF260ABED4C7002191D52FE5D1F3FD2D" xlink:to="loc_us-gaap_StockCompensationPlanMember_80A30BF8BDE2E494EB6B2FE5D1F318BB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_F67B21EE24B42865F8EB2FE5D1F37FCC" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_35E1911B36E47FEA9D792FE5D1F3F97C" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_F67B21EE24B42865F8EB2FE5D1F37FCC" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/NetIncomeLossPerShareScheduleOfEarningsPerShareBasicAndDilutedDetails" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/NetIncomeLossPerShareTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/NewAccountingPronouncements" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/NewAccountingPronouncementsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems" xlink:label="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_762EC4F47A6C16FCD928DE6FFE64B5D8" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable" xlink:label="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_8466A43972CA5484ECDDDE6FFE63FA73" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_762EC4F47A6C16FCD928DE6FFE64B5D8" xlink:to="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_8466A43972CA5484ECDDDE6FFE63FA73" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AdjustmentsForNewAccountingPronouncementsAxis" xlink:label="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_D043B1B45AD8CB4B0FF0DE6FFE64DE85" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_8466A43972CA5484ECDDDE6FFE63FA73" xlink:to="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_D043B1B45AD8CB4B0FF0DE6FFE64DE85" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_TypeOfAdoptionMember" xlink:label="loc_us-gaap_TypeOfAdoptionMember_BE971FA923F8E2AEDF93DE6FFE64E693_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_D043B1B45AD8CB4B0FF0DE6FFE64DE85" xlink:to="loc_us-gaap_TypeOfAdoptionMember_BE971FA923F8E2AEDF93DE6FFE64E693_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_TypeOfAdoptionMember" xlink:label="loc_us-gaap_TypeOfAdoptionMember_BE971FA923F8E2AEDF93DE6FFE64E693" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_D043B1B45AD8CB4B0FF0DE6FFE64DE85" xlink:to="loc_us-gaap_TypeOfAdoptionMember_BE971FA923F8E2AEDF93DE6FFE64E693" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccountingStandardsUpdate201616Member" xlink:label="loc_us-gaap_AccountingStandardsUpdate201616Member_271D00CE1E44B42976C2DE6FFE64CE8F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TypeOfAdoptionMember_BE971FA923F8E2AEDF93DE6FFE64E693" xlink:to="loc_us-gaap_AccountingStandardsUpdate201616Member_271D00CE1E44B42976C2DE6FFE64CE8F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementScenarioAxis" xlink:label="loc_us-gaap_StatementScenarioAxis_5A9B9576E4A69E87D114DE6FFE64F5BD" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_8466A43972CA5484ECDDDE6FFE63FA73" xlink:to="loc_us-gaap_StatementScenarioAxis_5A9B9576E4A69E87D114DE6FFE64F5BD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScenarioUnspecifiedDomain" xlink:label="loc_us-gaap_ScenarioUnspecifiedDomain_72211A10A870AB16BD82DE6FFE64FB5C_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementScenarioAxis_5A9B9576E4A69E87D114DE6FFE64F5BD" xlink:to="loc_us-gaap_ScenarioUnspecifiedDomain_72211A10A870AB16BD82DE6FFE64FB5C_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScenarioUnspecifiedDomain" xlink:label="loc_us-gaap_ScenarioUnspecifiedDomain_72211A10A870AB16BD82DE6FFE64FB5C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementScenarioAxis_5A9B9576E4A69E87D114DE6FFE64F5BD" xlink:to="loc_us-gaap_ScenarioUnspecifiedDomain_72211A10A870AB16BD82DE6FFE64FB5C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScenarioForecastMember" xlink:label="loc_us-gaap_ScenarioForecastMember_C397E94AEFB29DC07A14DE6FFE6478E3" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScenarioUnspecifiedDomain_72211A10A870AB16BD82DE6FFE64FB5C" xlink:to="loc_us-gaap_ScenarioForecastMember_C397E94AEFB29DC07A14DE6FFE6478E3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NewAccountingPronouncementOrChangeInAccountingPrincipleCumulativeEffectOfChangeOnEquityOrNetAssets1" xlink:label="loc_us-gaap_NewAccountingPronouncementOrChangeInAccountingPrincipleCumulativeEffectOfChangeOnEquityOrNetAssets1_681BCCDC9ECA47417CD5DE6FFE6469A9" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_762EC4F47A6C16FCD928DE6FFE64B5D8" xlink:to="loc_us-gaap_NewAccountingPronouncementOrChangeInAccountingPrincipleCumulativeEffectOfChangeOnEquityOrNetAssets1_681BCCDC9ECA47417CD5DE6FFE6469A9" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/ProductRemediationLiability" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/ProductRemediationLiabilityDetails" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/ProductRemediationLiabilityTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/Restructuring" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/RestructuringAccrualDetailDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="loc_us-gaap_RestructuringCostAndReserveLineItems_8B8CA86E9F6D79D565982FE5D269DE4C" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_358036456DD99AE857BF2FE5D268659F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_8B8CA86E9F6D79D565982FE5D269DE4C" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_358036456DD99AE857BF2FE5D268659F" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringPlanAxis" xlink:label="loc_us-gaap_RestructuringPlanAxis_4E8245FEA52977CB012A2FE5D26838A0" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_358036456DD99AE857BF2FE5D268659F" xlink:to="loc_us-gaap_RestructuringPlanAxis_4E8245FEA52977CB012A2FE5D26838A0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringPlanDomain" xlink:label="loc_us-gaap_RestructuringPlanDomain_900B5C8809502A79C5222FE5D269AF6F_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RestructuringPlanAxis_4E8245FEA52977CB012A2FE5D26838A0" xlink:to="loc_us-gaap_RestructuringPlanDomain_900B5C8809502A79C5222FE5D269AF6F_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringPlanDomain" xlink:label="loc_us-gaap_RestructuringPlanDomain_900B5C8809502A79C5222FE5D269AF6F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RestructuringPlanAxis_4E8245FEA52977CB012A2FE5D26838A0" xlink:to="loc_us-gaap_RestructuringPlanDomain_900B5C8809502A79C5222FE5D269AF6F" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_TwoThousandFifteenandSixteenReorganizationPlansMember" xlink:label="loc_livn_TwoThousandFifteenandSixteenReorganizationPlansMember_20371B76E60C7E0C678F2FE5D269F160" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringPlanDomain_900B5C8809502A79C5222FE5D269AF6F" xlink:to="loc_livn_TwoThousandFifteenandSixteenReorganizationPlansMember_20371B76E60C7E0C678F2FE5D269F160" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCostAndReserveAxis" xlink:label="loc_us-gaap_RestructuringCostAndReserveAxis_8F70EBB2EBE2516EEC8C2FE5D2696DB3" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_358036456DD99AE857BF2FE5D268659F" xlink:to="loc_us-gaap_RestructuringCostAndReserveAxis_8F70EBB2EBE2516EEC8C2FE5D2696DB3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="loc_us-gaap_TypeOfRestructuringDomain_9AC88928618676704F232FE5D269C621_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RestructuringCostAndReserveAxis_8F70EBB2EBE2516EEC8C2FE5D2696DB3" xlink:to="loc_us-gaap_TypeOfRestructuringDomain_9AC88928618676704F232FE5D269C621_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="loc_us-gaap_TypeOfRestructuringDomain_9AC88928618676704F232FE5D269C621" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RestructuringCostAndReserveAxis_8F70EBB2EBE2516EEC8C2FE5D2696DB3" xlink:to="loc_us-gaap_TypeOfRestructuringDomain_9AC88928618676704F232FE5D269C621" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EmployeeSeveranceMember" xlink:label="loc_us-gaap_EmployeeSeveranceMember_5E69E8CBA7FE01DE4E522FE5D269CA60" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_9AC88928618676704F232FE5D269C621" xlink:to="loc_us-gaap_EmployeeSeveranceMember_5E69E8CBA7FE01DE4E522FE5D269CA60" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRestructuringMember" xlink:label="loc_us-gaap_OtherRestructuringMember_E32DACE2CDFC025819592FE5D26912FD" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_9AC88928618676704F232FE5D269C621" xlink:to="loc_us-gaap_OtherRestructuringMember_E32DACE2CDFC025819592FE5D26912FD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringReserveRollForward" xlink:label="loc_us-gaap_RestructuringReserveRollForward_1C4CC2ABF0AE61A7FBEF2FE5D2695FD8" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_8B8CA86E9F6D79D565982FE5D269DE4C" xlink:to="loc_us-gaap_RestructuringReserveRollForward_1C4CC2ABF0AE61A7FBEF2FE5D2695FD8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringReserve" xlink:label="loc_us-gaap_RestructuringReserve_71894FC6F374C5F922AC2FE5D2699ACF" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringReserveRollForward_1C4CC2ABF0AE61A7FBEF2FE5D2695FD8" xlink:to="loc_us-gaap_RestructuringReserve_71894FC6F374C5F922AC2FE5D2699ACF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_4F6FF80DA063C05E4D122FE5D269673B" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringReserveRollForward_1C4CC2ABF0AE61A7FBEF2FE5D2695FD8" xlink:to="loc_us-gaap_RestructuringCharges_4F6FF80DA063C05E4D122FE5D269673B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsForRestructuring" xlink:label="loc_us-gaap_PaymentsForRestructuring_A24A7064F29A5ED842102FE5D2697458" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringReserveRollForward_1C4CC2ABF0AE61A7FBEF2FE5D2695FD8" xlink:to="loc_us-gaap_PaymentsForRestructuring_A24A7064F29A5ED842102FE5D2697458" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/RestructuringNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="loc_us-gaap_RestructuringCostAndReserveLineItems_71876BE984F3A3D2EB24DE6FFF99405A" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_733A2247E15730467EDEDE6FFF988974" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_71876BE984F3A3D2EB24DE6FFF99405A" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_733A2247E15730467EDEDE6FFF988974" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringPlanAxis" xlink:label="loc_us-gaap_RestructuringPlanAxis_ED173DBD47EBBD854E97DE6FFF98D044" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_733A2247E15730467EDEDE6FFF988974" xlink:to="loc_us-gaap_RestructuringPlanAxis_ED173DBD47EBBD854E97DE6FFF98D044" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringPlanDomain" xlink:label="loc_us-gaap_RestructuringPlanDomain_175FA822198928A93150DE6FFF9891CC_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RestructuringPlanAxis_ED173DBD47EBBD854E97DE6FFF98D044" xlink:to="loc_us-gaap_RestructuringPlanDomain_175FA822198928A93150DE6FFF9891CC_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringPlanDomain" xlink:label="loc_us-gaap_RestructuringPlanDomain_175FA822198928A93150DE6FFF9891CC" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RestructuringPlanAxis_ED173DBD47EBBD854E97DE6FFF98D044" xlink:to="loc_us-gaap_RestructuringPlanDomain_175FA822198928A93150DE6FFF9891CC" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_TwoThousandFifteenandSixteenReorganizationPlansMember" xlink:label="loc_livn_TwoThousandFifteenandSixteenReorganizationPlansMember_2958304392C05AF530AEDE6FFF986908" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringPlanDomain_175FA822198928A93150DE6FFF9891CC" xlink:to="loc_livn_TwoThousandFifteenandSixteenReorganizationPlansMember_2958304392C05AF530AEDE6FFF986908" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_B4B78223A6202D3266C1DE6FFF98612B" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_733A2247E15730467EDEDE6FFF988974" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_B4B78223A6202D3266C1DE6FFF98612B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_2AB4831B12B384263496DE6FFF985287_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_B4B78223A6202D3266C1DE6FFF98612B" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_2AB4831B12B384263496DE6FFF985287_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_2AB4831B12B384263496DE6FFF985287" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_B4B78223A6202D3266C1DE6FFF98612B" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_2AB4831B12B384263496DE6FFF985287" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_SuzhouIndustrialParkFacilityMember" xlink:label="loc_livn_SuzhouIndustrialParkFacilityMember_725DC65669FFBAF3A5A4DE6FFF98A1E5" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_2AB4831B12B384263496DE6FFF985287" xlink:to="loc_livn_SuzhouIndustrialParkFacilityMember_725DC65669FFBAF3A5A4DE6FFF98A1E5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PropertyPlantAndEquipmentByTypeAxis" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_D28C5CA694ED3E7122FDDE6FFF988EDF" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_733A2247E15730467EDEDE6FFF988974" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_D28C5CA694ED3E7122FDDE6FFF988EDF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PropertyPlantAndEquipmentTypeDomain" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_38AD0EF62F2CC02D2C96DE6FFF9850E6_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_D28C5CA694ED3E7122FDDE6FFF988EDF" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_38AD0EF62F2CC02D2C96DE6FFF9850E6_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PropertyPlantAndEquipmentTypeDomain" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_38AD0EF62F2CC02D2C96DE6FFF9850E6" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_D28C5CA694ED3E7122FDDE6FFF988EDF" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_38AD0EF62F2CC02D2C96DE6FFF9850E6" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_BuildingandEquipmentMember" xlink:label="loc_livn_BuildingandEquipmentMember_51CAB1A8D1B1011B3FC8DE6FFF98C03A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_38AD0EF62F2CC02D2C96DE6FFF9850E6" xlink:to="loc_livn_BuildingandEquipmentMember_51CAB1A8D1B1011B3FC8DE6FFF98C03A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LandMember" xlink:label="loc_us-gaap_LandMember_01864826A47B3D8D0A49DE6FFF98C79D" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_38AD0EF62F2CC02D2C96DE6FFF9850E6" xlink:to="loc_us-gaap_LandMember_01864826A47B3D8D0A49DE6FFF98C79D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringAndRelatedCostExpectedNumberOfPositionsEliminated" xlink:label="loc_us-gaap_RestructuringAndRelatedCostExpectedNumberOfPositionsEliminated_3C8C78B5D94B5A54AF21DE6FFF99287A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_71876BE984F3A3D2EB24DE6FFF99405A" xlink:to="loc_us-gaap_RestructuringAndRelatedCostExpectedNumberOfPositionsEliminated_3C8C78B5D94B5A54AF21DE6FFF99287A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringAndRelatedCostNumberOfPositionsEliminated" xlink:label="loc_us-gaap_RestructuringAndRelatedCostNumberOfPositionsEliminated_69EBD9945B81C10DCC0FDE6FFF9994DB" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_71876BE984F3A3D2EB24DE6FFF99405A" xlink:to="loc_us-gaap_RestructuringAndRelatedCostNumberOfPositionsEliminated_69EBD9945B81C10DCC0FDE6FFF9994DB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetImpairmentCharges" xlink:label="loc_us-gaap_AssetImpairmentCharges_54EB79FF25FD68E6EBD9DE6FFF999B67" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_71876BE984F3A3D2EB24DE6FFF99405A" xlink:to="loc_us-gaap_AssetImpairmentCharges_54EB79FF25FD68E6EBD9DE6FFF999B67" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SeveranceCosts1" xlink:label="loc_us-gaap_SeveranceCosts1_7CC39EA8708D80A1C2C5DE6FFF9932DD" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_71876BE984F3A3D2EB24DE6FFF99405A" xlink:to="loc_us-gaap_SeveranceCosts1_7CC39EA8708D80A1C2C5DE6FFF9932DD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetsHeldForSaleNotPartOfDisposalGroup" xlink:label="loc_us-gaap_AssetsHeldForSaleNotPartOfDisposalGroup_9C0E7C7399EE1EB9ADB6DE6FFF99AB6B" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_71876BE984F3A3D2EB24DE6FFF99405A" xlink:to="loc_us-gaap_AssetsHeldForSaleNotPartOfDisposalGroup_9C0E7C7399EE1EB9ADB6DE6FFF99AB6B" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/RestructuringRestructuringExpenseBySegmentDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="loc_us-gaap_RestructuringCostAndReserveLineItems_74E91F33AC755EA8A78DEEC96A6928FB" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_03E0640320DC5B349D24A8D88146ADA1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_74E91F33AC755EA8A78DEEC96A6928FB" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_03E0640320DC5B349D24A8D88146ADA1" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ConsolidationItemsAxis" xlink:label="loc_us-gaap_ConsolidationItemsAxis_1E2E096A64D956E5A19DCFD02636E0F3" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_03E0640320DC5B349D24A8D88146ADA1" xlink:to="loc_us-gaap_ConsolidationItemsAxis_1E2E096A64D956E5A19DCFD02636E0F3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ConsolidationItemsDomain" xlink:label="loc_us-gaap_ConsolidationItemsDomain_3C43A11F2A7D64E3EEC7B5C525485140_BEECA28EC1465A3CB0E29196CA2C2F8C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ConsolidationItemsAxis_1E2E096A64D956E5A19DCFD02636E0F3" xlink:to="loc_us-gaap_ConsolidationItemsDomain_3C43A11F2A7D64E3EEC7B5C525485140_BEECA28EC1465A3CB0E29196CA2C2F8C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ConsolidationItemsDomain" xlink:label="loc_us-gaap_ConsolidationItemsDomain_B069A639D9555BCFBBC7B7C51C04880E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ConsolidationItemsAxis_1E2E096A64D956E5A19DCFD02636E0F3" xlink:to="loc_us-gaap_ConsolidationItemsDomain_B069A639D9555BCFBBC7B7C51C04880E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OperatingSegmentsMember" xlink:label="loc_us-gaap_OperatingSegmentsMember_194A253E03A3557CBB9506570831D373" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ConsolidationItemsDomain_B069A639D9555BCFBBC7B7C51C04880E" xlink:to="loc_us-gaap_OperatingSegmentsMember_194A253E03A3557CBB9506570831D373" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CorporateNonSegmentMember" xlink:label="loc_us-gaap_CorporateNonSegmentMember_80483C2251A6504694314B99D7580E49" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ConsolidationItemsDomain_B069A639D9555BCFBBC7B7C51C04880E" xlink:to="loc_us-gaap_CorporateNonSegmentMember_80483C2251A6504694314B99D7580E49" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_5ED42B715CAF55BFA98A4A4C8F06075A" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_03E0640320DC5B349D24A8D88146ADA1" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_5ED42B715CAF55BFA98A4A4C8F06075A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_24E37FB1725FE9DD6448B5C52548D8FF_BEECA28EC1465A3CB0E29196CA2C2F8C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_5ED42B715CAF55BFA98A4A4C8F06075A" xlink:to="loc_us-gaap_SegmentDomain_24E37FB1725FE9DD6448B5C52548D8FF_BEECA28EC1465A3CB0E29196CA2C2F8C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_5FD1A758679C58FB828A9DC09B3B32B7" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_5ED42B715CAF55BFA98A4A4C8F06075A" xlink:to="loc_us-gaap_SegmentDomain_5FD1A758679C58FB828A9DC09B3B32B7" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_CardiacSurgeryMember" xlink:label="loc_livn_CardiacSurgeryMember_CA5921B37F875B6490EE40008CFA2370" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_5FD1A758679C58FB828A9DC09B3B32B7" xlink:to="loc_livn_CardiacSurgeryMember_CA5921B37F875B6490EE40008CFA2370" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_CardiacRhythmManagementMember" xlink:label="loc_livn_CardiacRhythmManagementMember_5EE22C0A775B5EC1B2F4CA2F28F51624" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_5FD1A758679C58FB828A9DC09B3B32B7" xlink:to="loc_livn_CardiacRhythmManagementMember_5EE22C0A775B5EC1B2F4CA2F28F51624" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_NeuromodulationMember" xlink:label="loc_livn_NeuromodulationMember_F0F0EE61467E54288207F3E3D78E8FF0" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_5FD1A758679C58FB828A9DC09B3B32B7" xlink:to="loc_livn_NeuromodulationMember_F0F0EE61467E54288207F3E3D78E8FF0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_9A5204FF8DD459EFA2D9C1EB404B4EDE" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_74E91F33AC755EA8A78DEEC96A6928FB" xlink:to="loc_us-gaap_RestructuringCharges_9A5204FF8DD459EFA2D9C1EB404B4EDE" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/RestructuringTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/StockBasedIncentivePlanCompensationExpenseDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_77B256073B675F35E5E45502E27F5EC3" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_D8E4DAB0D75849ED0E335502E27F5379" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_77B256073B675F35E5E45502E27F5EC3" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_D8E4DAB0D75849ED0E335502E27F5379" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_4112C218938291F627AA5502E27F8F8F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_D8E4DAB0D75849ED0E335502E27F5379" xlink:to="loc_us-gaap_AwardTypeAxis_4112C218938291F627AA5502E27F8F8F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_6B7DF8738ED1F576E5215502E27F63EE_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_AwardTypeAxis_4112C218938291F627AA5502E27F8F8F" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_6B7DF8738ED1F576E5215502E27F63EE_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_6B7DF8738ED1F576E5215502E27F63EE" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_AwardTypeAxis_4112C218938291F627AA5502E27F8F8F" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_6B7DF8738ED1F576E5215502E27F63EE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StockAppreciationRightsSARSMember" xlink:label="loc_us-gaap_StockAppreciationRightsSARSMember_C179D2A929C7677242215502E27FBF4C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_6B7DF8738ED1F576E5215502E27F63EE" xlink:to="loc_us-gaap_StockAppreciationRightsSARSMember_C179D2A929C7677242215502E27FBF4C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestrictedStockUnitsRSUMember" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_1E46243B11D61276B1335502E27FE71E" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_6B7DF8738ED1F576E5215502E27F63EE" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_1E46243B11D61276B1335502E27FE71E" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_MarketbasedPerformanceRestrictedStockUnitsMember" xlink:label="loc_livn_MarketbasedPerformanceRestrictedStockUnitsMember_654BCBA16B8CEC4A7C1D5502E27F0F67" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_6B7DF8738ED1F576E5215502E27F63EE" xlink:to="loc_livn_MarketbasedPerformanceRestrictedStockUnitsMember_654BCBA16B8CEC4A7C1D5502E27F0F67" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_OperatingPerformancebasedRestrictedStockUnitsMember" xlink:label="loc_livn_OperatingPerformancebasedRestrictedStockUnitsMember_96ADB64FB609068486685502E27FB5F5" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_6B7DF8738ED1F576E5215502E27F63EE" xlink:to="loc_livn_OperatingPerformancebasedRestrictedStockUnitsMember_96ADB64FB609068486685502E27FB5F5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AllocatedShareBasedCompensationExpense" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_8F31AAA7A150B07ACA905502E27F112E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_77B256073B675F35E5E45502E27F5EC3" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_8F31AAA7A150B07ACA905502E27F112E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardCompensationCost1" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardCompensationCost1_CA39AF02268A24290CBC5502E27FB18A" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_77B256073B675F35E5E45502E27F5EC3" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardCompensationCost1_CA39AF02268A24290CBC5502E27FB18A" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/StockBasedIncentivePlanExecutedAgreementsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_342953DBBABCEB6580685502E27C8854" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_48DB1063787755DD86B95502E27BA6F0" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_342953DBBABCEB6580685502E27C8854" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_48DB1063787755DD86B95502E27BA6F0" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_37AB3F3529A8C000E5AB5502E27BBBA8" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_48DB1063787755DD86B95502E27BA6F0" xlink:to="loc_us-gaap_AwardTypeAxis_37AB3F3529A8C000E5AB5502E27BBBA8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_2EE447DE8A5C3890FF7C5502E27B7ED2_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_AwardTypeAxis_37AB3F3529A8C000E5AB5502E27BBBA8" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_2EE447DE8A5C3890FF7C5502E27B7ED2_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_2EE447DE8A5C3890FF7C5502E27B7ED2" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_AwardTypeAxis_37AB3F3529A8C000E5AB5502E27BBBA8" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_2EE447DE8A5C3890FF7C5502E27B7ED2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StockAppreciationRightsSARSMember" xlink:label="loc_us-gaap_StockAppreciationRightsSARSMember_51BDC8F3179395118C955502E27CC4A9" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_2EE447DE8A5C3890FF7C5502E27B7ED2" xlink:to="loc_us-gaap_StockAppreciationRightsSARSMember_51BDC8F3179395118C955502E27CC4A9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RestrictedStockUnitsRSUMember" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_617D6C55C7F98F4203EB5502E27C2B18" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_2EE447DE8A5C3890FF7C5502E27B7ED2" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_617D6C55C7F98F4203EB5502E27C2B18" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_MarketbasedPerformanceRestrictedStockUnitsMember" xlink:label="loc_livn_MarketbasedPerformanceRestrictedStockUnitsMember_86FC72656A87303C94085502E27CD454" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_2EE447DE8A5C3890FF7C5502E27B7ED2" xlink:to="loc_livn_MarketbasedPerformanceRestrictedStockUnitsMember_86FC72656A87303C94085502E27CD454" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_OperatingPerformancebasedRestrictedStockUnitsMember" xlink:label="loc_livn_OperatingPerformancebasedRestrictedStockUnitsMember_8C68914231FE56C251CC5502E27C42B8" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_2EE447DE8A5C3890FF7C5502E27B7ED2" xlink:to="loc_livn_OperatingPerformancebasedRestrictedStockUnitsMember_8C68914231FE56C251CC5502E27C42B8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_A2B2A5734A64157E548F5502E27C100A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_342953DBBABCEB6580685502E27C8854" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_A2B2A5734A64157E548F5502E27C100A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_AD4EE3E528AE8306030A5502E27CBBBF" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_342953DBBABCEB6580685502E27C8854" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_AD4EE3E528AE8306030A5502E27CBBBF" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/StockBasedIncentivePlanTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/StockBasedIncentivePlans" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/StockholdersEquity" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/StockholdersEquityComprehensiveIncomeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_3CAA4489A1569730AA257305FC4DD5F6" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossTable" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_F20B6DEBA7FB4E4E56F67305FC47D9D3" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_3CAA4489A1569730AA257305FC4DD5F6" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_F20B6DEBA7FB4E4E56F67305FC47D9D3" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_3990AF24E758959807847305FC4CD32F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_F20B6DEBA7FB4E4E56F67305FC47D9D3" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_3990AF24E758959807847305FC4CD32F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_FD2918EF1D6F5E9E7B297305FC4C7D3C_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_3990AF24E758959807847305FC4CD32F" xlink:to="loc_us-gaap_EquityComponentDomain_FD2918EF1D6F5E9E7B297305FC4C7D3C_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_FD2918EF1D6F5E9E7B297305FC4C7D3C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_3990AF24E758959807847305FC4CD32F" xlink:to="loc_us-gaap_EquityComponentDomain_FD2918EF1D6F5E9E7B297305FC4C7D3C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccumulatedNetGainLossFromDesignatedOrQualifyingCashFlowHedgesMember" xlink:label="loc_us-gaap_AccumulatedNetGainLossFromDesignatedOrQualifyingCashFlowHedgesMember_C9EA209A8751F59DB3ED7305FC4D00C7" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_FD2918EF1D6F5E9E7B297305FC4C7D3C" xlink:to="loc_us-gaap_AccumulatedNetGainLossFromDesignatedOrQualifyingCashFlowHedgesMember_C9EA209A8751F59DB3ED7305FC4D00C7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccumulatedTranslationAdjustmentMember" xlink:label="loc_us-gaap_AccumulatedTranslationAdjustmentMember_8163C3FBF299EEA10E637305FC4D2A0A" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_FD2918EF1D6F5E9E7B297305FC4C7D3C" xlink:to="loc_us-gaap_AccumulatedTranslationAdjustmentMember_8163C3FBF299EEA10E637305FC4D2A0A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_60ACDE53AF3447A2DA6A7305FC4DD417" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_FD2918EF1D6F5E9E7B297305FC4C7D3C" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_60ACDE53AF3447A2DA6A7305FC4DD417" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_AccumulatedOtherComprehensiveIncomeLossRollForward" xlink:label="loc_livn_AccumulatedOtherComprehensiveIncomeLossRollForward_D1E20B1882908D621B2E7305FC4D08A4" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_3CAA4489A1569730AA257305FC4DD5F6" xlink:to="loc_livn_AccumulatedOtherComprehensiveIncomeLossRollForward_D1E20B1882908D621B2E7305FC4D08A4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_41EA0FB68D96AFB14FB37305FC4D167E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_livn_AccumulatedOtherComprehensiveIncomeLossRollForward_D1E20B1882908D621B2E7305FC4D08A4" xlink:to="loc_us-gaap_StockholdersEquity_41EA0FB68D96AFB14FB37305FC4D167E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsBeforeTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsBeforeTax_E0ACE6732F23DC2BA18B7305FC4DF42F" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_livn_AccumulatedOtherComprehensiveIncomeLossRollForward_D1E20B1882908D621B2E7305FC4D08A4" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsBeforeTax_E0ACE6732F23DC2BA18B7305FC4DF42F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsTax_5F6E3061DC4A420139537305FC4D356B" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_livn_AccumulatedOtherComprehensiveIncomeLossRollForward_D1E20B1882908D621B2E7305FC4D08A4" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsTax_5F6E3061DC4A420139537305FC4D356B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax_342587CBB733C07F12C67305FC4D4740" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_livn_AccumulatedOtherComprehensiveIncomeLossRollForward_D1E20B1882908D621B2E7305FC4D08A4" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax_342587CBB733C07F12C67305FC4D4740" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodBeforeTax" xlink:label="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodBeforeTax_919429FD1A0CFB30DA707305FC4D09D5" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_livn_AccumulatedOtherComprehensiveIncomeLossRollForward_D1E20B1882908D621B2E7305FC4D08A4" xlink:to="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodBeforeTax_919429FD1A0CFB30DA707305FC4D09D5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ReclassificationFromAociCurrentPeriodTax" xlink:label="loc_us-gaap_ReclassificationFromAociCurrentPeriodTax_23D146A6E05D53887F817305FC4DEDC2" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_livn_AccumulatedOtherComprehensiveIncomeLossRollForward_D1E20B1882908D621B2E7305FC4D08A4" xlink:to="loc_us-gaap_ReclassificationFromAociCurrentPeriodTax_23D146A6E05D53887F817305FC4DEDC2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax" xlink:label="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_DFE3E7A1F6F964657D007305FC4DD8AC" xlink:type="locator" />
    <link:definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_livn_AccumulatedOtherComprehensiveIncomeLossRollForward_D1E20B1882908D621B2E7305FC4D08A4" xlink:to="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_DFE3E7A1F6F964657D007305FC4DD8AC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_8D67B7A889BAABC6ECD77305FC4DF94B" xlink:type="locator" />
    <link:definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_livn_AccumulatedOtherComprehensiveIncomeLossRollForward_D1E20B1882908D621B2E7305FC4D08A4" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_8D67B7A889BAABC6ECD77305FC4DF94B" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/StockholdersEquityTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformation" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationSummaryOfAccountsReceivableDetails" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationSummaryOfAccruedLiabilitiesDetails" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationSummaryOfInventoryDetails" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationSummaryOfOtherLongTermAssetsDetails" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationSummaryOfOtherLongTermLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_F995470D150741F3EC0FB952371A7596" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_6DA0FB0F2D30D7FC25CEB952371A1767" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_F995470D150741F3EC0FB952371A7596" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_6DA0FB0F2D30D7FC25CEB952371A1767" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_LegalEntityAxis" xlink:label="loc_dei_LegalEntityAxis_E86C9DEADEA085FD14B5B952371A4647" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_6DA0FB0F2D30D7FC25CEB952371A1767" xlink:to="loc_dei_LegalEntityAxis_E86C9DEADEA085FD14B5B952371A4647" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityDomain" xlink:label="loc_dei_EntityDomain_109930DEE2AFF219EE4AB952371A846F_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_dei_LegalEntityAxis_E86C9DEADEA085FD14B5B952371A4647" xlink:to="loc_dei_EntityDomain_109930DEE2AFF219EE4AB952371A846F_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.sec.gov/dei/2014/dei-2014-01-31.xsd#dei_EntityDomain" xlink:label="loc_dei_EntityDomain_109930DEE2AFF219EE4AB952371A846F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_dei_LegalEntityAxis_E86C9DEADEA085FD14B5B952371A4647" xlink:to="loc_dei_EntityDomain_109930DEE2AFF219EE4AB952371A846F" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_SorinS.p.A.Member" xlink:label="loc_livn_SorinS.p.A.Member_8E3C5DBFAA167AC7CD94B952371A98BE" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityDomain_109930DEE2AFF219EE4AB952371A846F" xlink:to="loc_livn_SorinS.p.A.Member_8E3C5DBFAA167AC7CD94B952371A98BE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_51A8233F43083AC96CA2B952371A14F1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_F995470D150741F3EC0FB952371A7596" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiabilityNoncurrent_51A8233F43083AC96CA2B952371A14F1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilityForUncertainTaxPositionsNoncurrent" xlink:label="loc_us-gaap_LiabilityForUncertainTaxPositionsNoncurrent_71F86808FE5FED6138EDB952371A1B5C" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_F995470D150741F3EC0FB952371A7596" xlink:to="loc_us-gaap_LiabilityForUncertainTaxPositionsNoncurrent_71F86808FE5FED6138EDB952371A1B5C" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_A3THeaterCoolerRecallLiability" xlink:label="loc_livn_A3THeaterCoolerRecallLiability_ECDCADB38CE675360DACB952371A5E91" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_F995470D150741F3EC0FB952371A7596" xlink:to="loc_livn_A3THeaterCoolerRecallLiability_ECDCADB38CE675360DACB952371A5E91" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredRevenueNoncurrent" xlink:label="loc_us-gaap_DeferredRevenueNoncurrent_242123110B84EEB0A733B952371AB1E1" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_F995470D150741F3EC0FB952371A7596" xlink:to="loc_us-gaap_DeferredRevenueNoncurrent_242123110B84EEB0A733B952371AB1E1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgesLiabilitiesNoncurrent" xlink:label="loc_us-gaap_DerivativeInstrumentsAndHedgesLiabilitiesNoncurrent_287647BC6983E492960FB952371AD3AC" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_F995470D150741F3EC0FB952371A7596" xlink:to="loc_us-gaap_DerivativeInstrumentsAndHedgesLiabilitiesNoncurrent_287647BC6983E492960FB952371AD3AC" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_EscrowIndemnityLiabilityNoncurrent" xlink:label="loc_livn_EscrowIndemnityLiabilityNoncurrent_35EE2B161194B75EA203B952371A4DF5" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_F995470D150741F3EC0FB952371A7596" xlink:to="loc_livn_EscrowIndemnityLiabilityNoncurrent_35EE2B161194B75EA203B952371A4DF5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OffMarketLeaseUnfavorable" xlink:label="loc_us-gaap_OffMarketLeaseUnfavorable_32751A8991F345BB1DACB952371A8615" xlink:type="locator" />
    <link:definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_F995470D150741F3EC0FB952371A7596" xlink:to="loc_us-gaap_OffMarketLeaseUnfavorable_32751A8991F345BB1DACB952371A8615" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherSundryLiabilitiesNoncurrent" xlink:label="loc_us-gaap_OtherSundryLiabilitiesNoncurrent_62BFBE09E1172C548554B952371A65A6" xlink:type="locator" />
    <link:definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_F995470D150741F3EC0FB952371A7596" xlink:to="loc_us-gaap_OtherSundryLiabilitiesNoncurrent_62BFBE09E1172C548554B952371A65A6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherLiabilitiesNoncurrent" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_1D83DA2DB965B4366AF1B952371A279F" xlink:type="locator" />
    <link:definitionArc order="9" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_F995470D150741F3EC0FB952371A7596" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_1D83DA2DB965B4366AF1B952371A279F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NumberOfBusinessesAcquired" xlink:label="loc_us-gaap_NumberOfBusinessesAcquired_ACBCDF7DC9C38C2F26AFB952371B4AB7" xlink:type="locator" />
    <link:definitionArc order="10" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_F995470D150741F3EC0FB952371A7596" xlink:to="loc_us-gaap_NumberOfBusinessesAcquired_ACBCDF7DC9C38C2F26AFB952371B4AB7" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationSummaryOfPrepaidExpensesAndOtherAssetsDetails" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/UnauditedCondensedConsolidatedFinancialStatements" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/UnauditedCondensedConsolidatedFinancialStatementsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems" xlink:label="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_3C9B2E127707C1C7EB4E6F47AE2E43A3" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ScheduleOfErrorCorrectionsAndPriorPeriodAdjustmentRestatementTable" xlink:label="loc_us-gaap_ScheduleOfErrorCorrectionsAndPriorPeriodAdjustmentRestatementTable_3DF23B170DC6E2BE38C16F47AE2EC005" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_3C9B2E127707C1C7EB4E6F47AE2E43A3" xlink:to="loc_us-gaap_ScheduleOfErrorCorrectionsAndPriorPeriodAdjustmentRestatementTable_3DF23B170DC6E2BE38C16F47AE2EC005" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_A666746AAD9CBA4A04BD6F47AE2EC4E1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfErrorCorrectionsAndPriorPeriodAdjustmentRestatementTable_3DF23B170DC6E2BE38C16F47AE2EC005" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_A666746AAD9CBA4A04BD6F47AE2EC4E1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_ECDECB4483DD930B82936F47AE2E7CA7_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_A666746AAD9CBA4A04BD6F47AE2EC4E1" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_ECDECB4483DD930B82936F47AE2E7CA7_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_ECDECB4483DD930B82936F47AE2E7CA7" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_A666746AAD9CBA4A04BD6F47AE2EC4E1" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_ECDECB4483DD930B82936F47AE2E7CA7" xlink:type="arc" />
    <link:loc xlink:href="livn-20170930.xsd#livn_CostofGoodsSoldProductRemediationMember" xlink:label="loc_livn_CostofGoodsSoldProductRemediationMember_3F2229E2F97EA62CE7BC6F47AE2E70F2" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_ECDECB4483DD930B82936F47AE2E7CA7" xlink:to="loc_livn_CostofGoodsSoldProductRemediationMember_3F2229E2F97EA62CE7BC6F47AE2E70F2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpensesMember" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_202E757CE79429AC4A306F47AE2E9126" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_ECDECB4483DD930B82936F47AE2E7CA7" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_202E757CE79429AC4A306F47AE2E9126" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LitigationSettlementExpense" xlink:label="loc_us-gaap_LitigationSettlementExpense_94DF9AD5E596600584E76F47AE2EB5C7" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_3C9B2E127707C1C7EB4E6F47AE2E43A3" xlink:to="loc_us-gaap_LitigationSettlementExpense_94DF9AD5E596600584E76F47AE2EB5C7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetsHeldForSaleNotPartOfDisposalGroup" xlink:label="loc_us-gaap_AssetsHeldForSaleNotPartOfDisposalGroup_AE4515D059F56216DD1C6F47AE2E1AA0" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_3C9B2E127707C1C7EB4E6F47AE2E43A3" xlink:to="loc_us-gaap_AssetsHeldForSaleNotPartOfDisposalGroup_AE4515D059F56216DD1C6F47AE2E1AA0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProceedsFromDivestitureOfBusinesses" xlink:label="loc_us-gaap_ProceedsFromDivestitureOfBusinesses_36627EAC9B1317D7846A6F47AE2E78B2" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_3C9B2E127707C1C7EB4E6F47AE2E43A3" xlink:to="loc_us-gaap_ProceedsFromDivestitureOfBusinesses_36627EAC9B1317D7846A6F47AE2E78B2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsForAdvanceToAffiliate" xlink:label="loc_us-gaap_PaymentsForAdvanceToAffiliate_6768B35DFCD902BBD2666F4AAED82D07" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ErrorCorrectionsAndPriorPeriodAdjustmentsRestatementLineItems_3C9B2E127707C1C7EB4E6F47AE2E43A3" xlink:to="loc_us-gaap_PaymentsForAdvanceToAffiliate_6768B35DFCD902BBD2666F4AAED82D07" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/UnauditedCondensedConsolidatedFinancialStatementsPolicies" xlink:type="extended" />
</link:linkbase>
