<?xml version="1.0" encoding="US-ASCII"?>
<!--XBRL Document Created with Wdesk from Workiva-->
<!-- -->
<link:linkbase xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/BusinessCombinations" xlink:href="livn-20200331.xsd#BusinessCombinations" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/BusinessCombinationsNarrativeDetails" xlink:href="livn-20200331.xsd#BusinessCombinationsNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/CommitmentsAndContingencies" xlink:href="livn-20200331.xsd#CommitmentsAndContingencies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/CommitmentsAndContingenciesNarrativeDetails" xlink:href="livn-20200331.xsd#CommitmentsAndContingenciesNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/CommitmentsAndContingenciesScheduleOfProductLiabilityDetails" xlink:href="livn-20200331.xsd#CommitmentsAndContingenciesScheduleOfProductLiabilityDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/CommitmentsAndContingenciesTables" xlink:href="livn-20200331.xsd#CommitmentsAndContingenciesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/CondensedConsolidatedBalanceSheets" xlink:href="livn-20200331.xsd#CondensedConsolidatedBalanceSheets" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/CondensedConsolidatedBalanceSheetsParenthetical" xlink:href="livn-20200331.xsd#CondensedConsolidatedBalanceSheetsParenthetical" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/CondensedConsolidatedStatementsOfCashFlows" xlink:href="livn-20200331.xsd#CondensedConsolidatedStatementsOfCashFlows" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/CondensedConsolidatedStatementsOfComprehensiveIncomeLoss" xlink:href="livn-20200331.xsd#CondensedConsolidatedStatementsOfComprehensiveIncomeLoss" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/CondensedConsolidatedStatementsOfIncomeLoss" xlink:href="livn-20200331.xsd#CondensedConsolidatedStatementsOfIncomeLoss" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/CoverPage" xlink:href="livn-20200331.xsd#CoverPage" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagement" xlink:href="livn-20200331.xsd#DerivativesAndRiskManagement" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementAmountOfGainLossRecognizedInOciAndIncomeStatementDetails" xlink:href="livn-20200331.xsd#DerivativesAndRiskManagementAmountOfGainLossRecognizedInOciAndIncomeStatementDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementDerivativeNotionalAmountsDetails" xlink:href="livn-20200331.xsd#DerivativesAndRiskManagementDerivativeNotionalAmountsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementFairValueOfDerivativeInstrumentsDetails" xlink:href="livn-20200331.xsd#DerivativesAndRiskManagementFairValueOfDerivativeInstrumentsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementNarrativeDetails" xlink:href="livn-20200331.xsd#DerivativesAndRiskManagementNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementTables" xlink:href="livn-20200331.xsd#DerivativesAndRiskManagementTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/DiscontinuedOperations" xlink:href="livn-20200331.xsd#DiscontinuedOperations" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/DiscontinuedOperationsNarrativeDetails" xlink:href="livn-20200331.xsd#DiscontinuedOperationsNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/DiscontinuedOperationsOperatingGainsAndLossesDetails" xlink:href="livn-20200331.xsd#DiscontinuedOperationsOperatingGainsAndLossesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/DiscontinuedOperationsTables" xlink:href="livn-20200331.xsd#DiscontinuedOperationsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/EarningsPerShare" xlink:href="livn-20200331.xsd#EarningsPerShare" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/EarningsPerShareNarrativeOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareDetails" xlink:href="livn-20200331.xsd#EarningsPerShareNarrativeOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/EarningsPerShareScheduleOfEarningsPerShareBasicAndDilutedDetails" xlink:href="livn-20200331.xsd#EarningsPerShareScheduleOfEarningsPerShareBasicAndDilutedDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/EarningsPerShareTables" xlink:href="livn-20200331.xsd#EarningsPerShareTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/FairValueMeasurements" xlink:href="livn-20200331.xsd#FairValueMeasurements" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/FairValueMeasurementsAssetsAndLiabilitiesMeasuredAtFairValueOnRecurringBasisDetails" xlink:href="livn-20200331.xsd#FairValueMeasurementsAssetsAndLiabilitiesMeasuredAtFairValueOnRecurringBasisDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/FairValueMeasurementsContingentConsiderationReconciliationDetails" xlink:href="livn-20200331.xsd#FairValueMeasurementsContingentConsiderationReconciliationDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/FairValueMeasurementsFairValueOfContingentConsiderationByAcquisitionDetails" xlink:href="livn-20200331.xsd#FairValueMeasurementsFairValueOfContingentConsiderationByAcquisitionDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/FairValueMeasurementsLevel3ValuationsDetails" xlink:href="livn-20200331.xsd#FairValueMeasurementsLevel3ValuationsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/FairValueMeasurementsTables" xlink:href="livn-20200331.xsd#FairValueMeasurementsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/FinancingArrangements" xlink:href="livn-20200331.xsd#FinancingArrangements" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/FinancingArrangementsNarrativeDetails" xlink:href="livn-20200331.xsd#FinancingArrangementsNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/FinancingArrangementsScheduleOfDebtDetails" xlink:href="livn-20200331.xsd#FinancingArrangementsScheduleOfDebtDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/FinancingArrangementsTables" xlink:href="livn-20200331.xsd#FinancingArrangementsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformation" xlink:href="livn-20200331.xsd#GeographicAndSegmentInformation" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformationChangesInCarryingAmountOfGoodwillDetails" xlink:href="livn-20200331.xsd#GeographicAndSegmentInformationChangesInCarryingAmountOfGoodwillDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformationGeographicAreasDetails" xlink:href="livn-20200331.xsd#GeographicAndSegmentInformationGeographicAreasDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformationSegmentInfoDetails" xlink:href="livn-20200331.xsd#GeographicAndSegmentInformationSegmentInfoDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformationTables" xlink:href="livn-20200331.xsd#GeographicAndSegmentInformationTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/IncomeTaxes" xlink:href="livn-20200331.xsd#IncomeTaxes" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/IncomeTaxesNarrativeDetails" xlink:href="livn-20200331.xsd#IncomeTaxesNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/Investments" xlink:href="livn-20200331.xsd#Investments" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/InvestmentsDetails" xlink:href="livn-20200331.xsd#InvestmentsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/InvestmentsTables" xlink:href="livn-20200331.xsd#InvestmentsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/NewAccountingPronouncements" xlink:href="livn-20200331.xsd#NewAccountingPronouncements" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/NewAccountingPronouncementsDetails" xlink:href="livn-20200331.xsd#NewAccountingPronouncementsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/NewAccountingPronouncementsTables" xlink:href="livn-20200331.xsd#NewAccountingPronouncementsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/ProductRemediationLiability" xlink:href="livn-20200331.xsd#ProductRemediationLiability" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/ProductRemediationLiabilityDetails" xlink:href="livn-20200331.xsd#ProductRemediationLiabilityDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/ProductRemediationLiabilityTables" xlink:href="livn-20200331.xsd#ProductRemediationLiabilityTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/Restructuring" xlink:href="livn-20200331.xsd#Restructuring" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/RestructuringRestructuringAndRelatedCostsDetails" xlink:href="livn-20200331.xsd#RestructuringRestructuringAndRelatedCostsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/RestructuringRestructuringExpenseBySegmentDetails" xlink:href="livn-20200331.xsd#RestructuringRestructuringExpenseBySegmentDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/RestructuringTables" xlink:href="livn-20200331.xsd#RestructuringTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/StockBasedIncentivePlans" xlink:href="livn-20200331.xsd#StockBasedIncentivePlans" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/StockBasedIncentivePlansCompensationExpenseDetails" xlink:href="livn-20200331.xsd#StockBasedIncentivePlansCompensationExpenseDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/StockBasedIncentivePlansExecutedAgreementsDetails" xlink:href="livn-20200331.xsd#StockBasedIncentivePlansExecutedAgreementsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/StockBasedIncentivePlansTables" xlink:href="livn-20200331.xsd#StockBasedIncentivePlansTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/StockholdersEquity" xlink:href="livn-20200331.xsd#StockholdersEquity" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/StockholdersEquityComprehensiveIncomeDetails" xlink:href="livn-20200331.xsd#StockholdersEquityComprehensiveIncomeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/StockholdersEquityStatementOfStockholdersEquityDetails" xlink:href="livn-20200331.xsd#StockholdersEquityStatementOfStockholdersEquityDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/StockholdersEquityTables" xlink:href="livn-20200331.xsd#StockholdersEquityTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformation" xlink:href="livn-20200331.xsd#SupplementalFinancialInformation" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationSummaryOfAccruedLiabilitiesDetails" xlink:href="livn-20200331.xsd#SupplementalFinancialInformationSummaryOfAccruedLiabilitiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationSummaryOfInventoryDetails" xlink:href="livn-20200331.xsd#SupplementalFinancialInformationSummaryOfInventoryDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationTables" xlink:href="livn-20200331.xsd#SupplementalFinancialInformationTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/UnauditedCondensedConsolidatedFinancialStatements" xlink:href="livn-20200331.xsd#UnauditedCondensedConsolidatedFinancialStatements" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/UnauditedCondensedConsolidatedFinancialStatementsNarrativeDetails" xlink:href="livn-20200331.xsd#UnauditedCondensedConsolidatedFinancialStatementsNarrativeDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.livanova.cyberonics.com/role/UnauditedCondensedConsolidatedFinancialStatementsPolicies" xlink:href="livn-20200331.xsd#UnauditedCondensedConsolidatedFinancialStatementsPolicies" xlink:type="simple" />
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/all" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#all" xlink:type="simple" />
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-default" xlink:type="simple" />
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-domain" xlink:type="simple" />
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/domain-member" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#domain-member" xlink:type="simple" />
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#hypercube-dimension" xlink:type="simple" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/BusinessCombinations" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/BusinessCombinationsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_43764DA6BCD53FDB4695BCD6E5B0481E" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_B4F68415E0E0B2362A4ABCD6E5AF9A82" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_43764DA6BCD53FDB4695BCD6E5B0481E" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_B4F68415E0E0B2362A4ABCD6E5AF9A82" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_D63E58C365A340C24096BCD6E5AF84A7" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_B4F68415E0E0B2362A4ABCD6E5AF9A82" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_D63E58C365A340C24096BCD6E5AF84A7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_D1A9531C635EF9ADB943BCD6E5AFAA3C_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_D63E58C365A340C24096BCD6E5AF84A7" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_D1A9531C635EF9ADB943BCD6E5AFAA3C_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_D1A9531C635EF9ADB943BCD6E5AFAA3C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_D63E58C365A340C24096BCD6E5AF84A7" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_D1A9531C635EF9ADB943BCD6E5AFAA3C" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_MiamiInstrumentsLLCMember" xlink:label="loc_livn_MiamiInstrumentsLLCMember_4D7E0B150A8AE6504174BCD6E5AF6791" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_D1A9531C635EF9ADB943BCD6E5AFAA3C" xlink:to="loc_livn_MiamiInstrumentsLLCMember_4D7E0B150A8AE6504174BCD6E5AF6791" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_D1AC75816EA785FA396CBCD6E5B00F1F" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_B4F68415E0E0B2362A4ABCD6E5AF9A82" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_D1AC75816EA785FA396CBCD6E5B00F1F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_44B6BDA52213D6580C51BCD6E5B0AFAB_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_D1AC75816EA785FA396CBCD6E5B00F1F" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_44B6BDA52213D6580C51BCD6E5B0AFAB_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_44B6BDA52213D6580C51BCD6E5B0AFAB" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_D1AC75816EA785FA396CBCD6E5B00F1F" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_44B6BDA52213D6580C51BCD6E5B0AFAB" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_DevelopedTechnologyRightsandInProcessResearchandDevelopmentMember" xlink:label="loc_livn_DevelopedTechnologyRightsandInProcessResearchandDevelopmentMember_61F044AC98CE9A8E8AE8BCD6E5B0409D" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_44B6BDA52213D6580C51BCD6E5B0AFAB" xlink:to="loc_livn_DevelopedTechnologyRightsandInProcessResearchandDevelopmentMember_61F044AC98CE9A8E8AE8BCD6E5B0409D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferred1" xlink:label="loc_us-gaap_BusinessCombinationConsiderationTransferred1_2C9B4830B756E1CA71C4BCD6E5B1589F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_43764DA6BCD53FDB4695BCD6E5B0481E" xlink:to="loc_us-gaap_BusinessCombinationConsiderationTransferred1_2C9B4830B756E1CA71C4BCD6E5B1589F" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_BusinessCombinationUpfrontCosts" xlink:label="loc_livn_BusinessCombinationUpfrontCosts_8212B3E71395C976B449BCD6E5B1320C" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_43764DA6BCD53FDB4695BCD6E5B0481E" xlink:to="loc_livn_BusinessCombinationUpfrontCosts_8212B3E71395C976B449BCD6E5B1320C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh_427D49032B786AEF4FC7BCD6E5B1C1FC" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_43764DA6BCD53FDB4695BCD6E5B0481E" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsRangeOfOutcomesValueHigh_427D49032B786AEF4FC7BCD6E5B1C1FC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinitelivedIntangibleAssetsAcquired1" xlink:label="loc_us-gaap_FinitelivedIntangibleAssetsAcquired1_8D440813E48F64B60482BCD6E5B1E52B" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_43764DA6BCD53FDB4695BCD6E5B0481E" xlink:to="loc_us-gaap_FinitelivedIntangibleAssetsAcquired1_8D440813E48F64B60482BCD6E5B1E52B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_A6CA04FB223276261B04BCD6E5B125E6" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_43764DA6BCD53FDB4695BCD6E5B0481E" xlink:to="loc_us-gaap_Goodwill_A6CA04FB223276261B04BCD6E5B125E6" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/CommitmentsAndContingencies" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/CommitmentsAndContingenciesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherCommitmentsLineItems" xlink:label="loc_us-gaap_OtherCommitmentsLineItems_CE1BB4237C1DC3F47F9CBD7B5D47EF4F" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherCommitmentsTable" xlink:label="loc_us-gaap_OtherCommitmentsTable_2F937CF1C4C53432A1C8BD7B5D3CD01A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_CE1BB4237C1DC3F47F9CBD7B5D47EF4F" xlink:to="loc_us-gaap_OtherCommitmentsTable_2F937CF1C4C53432A1C8BD7B5D3CD01A" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RelatedPartyTransactionAxis" xlink:label="loc_us-gaap_RelatedPartyTransactionAxis_A580AE3F44BCDF66C533BD7B5D3C5635" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_OtherCommitmentsTable_2F937CF1C4C53432A1C8BD7B5D3CD01A" xlink:to="loc_us-gaap_RelatedPartyTransactionAxis_A580AE3F44BCDF66C533BD7B5D3C5635" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RelatedPartyTransactionDomain" xlink:label="loc_us-gaap_RelatedPartyTransactionDomain_6A49A0256B06128B256EBD7B5D3D833E_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RelatedPartyTransactionAxis_A580AE3F44BCDF66C533BD7B5D3C5635" xlink:to="loc_us-gaap_RelatedPartyTransactionDomain_6A49A0256B06128B256EBD7B5D3D833E_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RelatedPartyTransactionDomain" xlink:label="loc_us-gaap_RelatedPartyTransactionDomain_6A49A0256B06128B256EBD7B5D3D833E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RelatedPartyTransactionAxis_A580AE3F44BCDF66C533BD7B5D3C5635" xlink:to="loc_us-gaap_RelatedPartyTransactionDomain_6A49A0256B06128B256EBD7B5D3D833E" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_SecondPaymentMember" xlink:label="loc_livn_SecondPaymentMember_0DDD368E50945ADD6B3BBD7B5D3D534C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_6A49A0256B06128B256EBD7B5D3D833E" xlink:to="loc_livn_SecondPaymentMember_0DDD368E50945ADD6B3BBD7B5D3D534C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SubsequentEventTypeAxis" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_5B45A9926D79432B367EBD7B5D3D0A99" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_OtherCommitmentsTable_2F937CF1C4C53432A1C8BD7B5D3CD01A" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_5B45A9926D79432B367EBD7B5D3D0A99" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SubsequentEventTypeDomain" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_5776672E280D96C79EEEBD7B5D3DD299_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_5B45A9926D79432B367EBD7B5D3D0A99" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_5776672E280D96C79EEEBD7B5D3DD299_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SubsequentEventTypeDomain" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_5776672E280D96C79EEEBD7B5D3DD299" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_5B45A9926D79432B367EBD7B5D3D0A99" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_5776672E280D96C79EEEBD7B5D3DD299" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SubsequentEventMember" xlink:label="loc_us-gaap_SubsequentEventMember_4B34FBD8A374BE21B0D7BD7B5D4378B0" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_5776672E280D96C79EEEBD7B5D3DD299" xlink:to="loc_us-gaap_SubsequentEventMember_4B34FBD8A374BE21B0D7BD7B5D4378B0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TaxPeriodAxis" xlink:label="loc_us-gaap_TaxPeriodAxis_4611966AD2A3DC940ECABD7B5D431AB7" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_OtherCommitmentsTable_2F937CF1C4C53432A1C8BD7B5D3CD01A" xlink:to="loc_us-gaap_TaxPeriodAxis_4611966AD2A3DC940ECABD7B5D431AB7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TaxPeriodDomain" xlink:label="loc_us-gaap_TaxPeriodDomain_A1B99BE9B6EF0291318FBD7B5D4312A7_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_TaxPeriodAxis_4611966AD2A3DC940ECABD7B5D431AB7" xlink:to="loc_us-gaap_TaxPeriodDomain_A1B99BE9B6EF0291318FBD7B5D4312A7_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TaxPeriodDomain" xlink:label="loc_us-gaap_TaxPeriodDomain_A1B99BE9B6EF0291318FBD7B5D4312A7" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_TaxPeriodAxis_4611966AD2A3DC940ECABD7B5D431AB7" xlink:to="loc_us-gaap_TaxPeriodDomain_A1B99BE9B6EF0291318FBD7B5D4312A7" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_TaxYears20022006Member" xlink:label="loc_livn_TaxYears20022006Member_5AE47A88EEE93AFACF31BD7B5D4372DD" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TaxPeriodDomain_A1B99BE9B6EF0291318FBD7B5D4312A7" xlink:to="loc_livn_TaxYears20022006Member_5AE47A88EEE93AFACF31BD7B5D4372DD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_LitigationCaseAxis" xlink:label="loc_srt_LitigationCaseAxis_8E353841B24F0F6403E9BD7B5D44E3E3" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_OtherCommitmentsTable_2F937CF1C4C53432A1C8BD7B5D3CD01A" xlink:to="loc_srt_LitigationCaseAxis_8E353841B24F0F6403E9BD7B5D44E3E3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="loc_srt_LitigationCaseTypeDomain_5BDB8261557AFF682077BD7B5D44DF75_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_LitigationCaseAxis_8E353841B24F0F6403E9BD7B5D44E3E3" xlink:to="loc_srt_LitigationCaseTypeDomain_5BDB8261557AFF682077BD7B5D44DF75_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="loc_srt_LitigationCaseTypeDomain_5BDB8261557AFF682077BD7B5D44DF75" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_LitigationCaseAxis_8E353841B24F0F6403E9BD7B5D44E3E3" xlink:to="loc_srt_LitigationCaseTypeDomain_5BDB8261557AFF682077BD7B5D44DF75" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_FDAWarningLetterMember" xlink:label="loc_livn_FDAWarningLetterMember_475A04E1746DD697A034BD7B5D44A53E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_LitigationCaseTypeDomain_5BDB8261557AFF682077BD7B5D44DF75" xlink:to="loc_livn_FDAWarningLetterMember_475A04E1746DD697A034BD7B5D44A53E" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_ProductLiabilityMember" xlink:label="loc_livn_ProductLiabilityMember_48CE36C87B1AB6BB2452BD7B5D44AE38" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_LitigationCaseTypeDomain_5BDB8261557AFF682077BD7B5D44DF75" xlink:to="loc_livn_ProductLiabilityMember_48CE36C87B1AB6BB2452BD7B5D44AE38" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_SNIAMember" xlink:label="loc_livn_SNIAMember_6925B4BA893AACA83D42BD7B5D441B8C" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_LitigationCaseTypeDomain_5BDB8261557AFF682077BD7B5D44DF75" xlink:to="loc_livn_SNIAMember_6925B4BA893AACA83D42BD7B5D441B8C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LitigationStatusAxis" xlink:label="loc_us-gaap_LitigationStatusAxis_4C332657AA777098AFF2BD7B5D45064B" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_OtherCommitmentsTable_2F937CF1C4C53432A1C8BD7B5D3CD01A" xlink:to="loc_us-gaap_LitigationStatusAxis_4C332657AA777098AFF2BD7B5D45064B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LitigationStatusDomain" xlink:label="loc_us-gaap_LitigationStatusDomain_99E04642112B4E9571D1BD7B5D452FC3_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LitigationStatusAxis_4C332657AA777098AFF2BD7B5D45064B" xlink:to="loc_us-gaap_LitigationStatusDomain_99E04642112B4E9571D1BD7B5D452FC3_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LitigationStatusDomain" xlink:label="loc_us-gaap_LitigationStatusDomain_99E04642112B4E9571D1BD7B5D452FC3" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LitigationStatusAxis_4C332657AA777098AFF2BD7B5D45064B" xlink:to="loc_us-gaap_LitigationStatusDomain_99E04642112B4E9571D1BD7B5D452FC3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PendingLitigationMember" xlink:label="loc_us-gaap_PendingLitigationMember_C932BAE6CC4505C6DF35BD7B5D45F650" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LitigationStatusDomain_99E04642112B4E9571D1BD7B5D452FC3" xlink:to="loc_us-gaap_PendingLitigationMember_C932BAE6CC4505C6DF35BD7B5D45F650" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SettledLitigationMember" xlink:label="loc_us-gaap_SettledLitigationMember_29CE6C57579CF12A5F41BD7B5D45510A" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LitigationStatusDomain_99E04642112B4E9571D1BD7B5D452FC3" xlink:to="loc_us-gaap_SettledLitigationMember_29CE6C57579CF12A5F41BD7B5D45510A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ThreatenedLitigationMember" xlink:label="loc_us-gaap_ThreatenedLitigationMember_E818242B81B51428BECDBD7B5D464DA1" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LitigationStatusDomain_99E04642112B4E9571D1BD7B5D452FC3" xlink:to="loc_us-gaap_ThreatenedLitigationMember_E818242B81B51428BECDBD7B5D464DA1" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_LegalEntityAxis" xlink:label="loc_dei_LegalEntityAxis_6E33F54001042EF8F5ABBD7B5D46C88D" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_OtherCommitmentsTable_2F937CF1C4C53432A1C8BD7B5D3CD01A" xlink:to="loc_dei_LegalEntityAxis_6E33F54001042EF8F5ABBD7B5D46C88D" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityDomain" xlink:label="loc_dei_EntityDomain_B9FF16D43A24467404DFBD7B5D46AF41_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_dei_LegalEntityAxis_6E33F54001042EF8F5ABBD7B5D46C88D" xlink:to="loc_dei_EntityDomain_B9FF16D43A24467404DFBD7B5D46AF41_default" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/dei/2019/dei-2019-01-31.xsd#dei_EntityDomain" xlink:label="loc_dei_EntityDomain_B9FF16D43A24467404DFBD7B5D46AF41" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_dei_LegalEntityAxis_6E33F54001042EF8F5ABBD7B5D46C88D" xlink:to="loc_dei_EntityDomain_B9FF16D43A24467404DFBD7B5D46AF41" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_SNIAs.p.aMember" xlink:label="loc_livn_SNIAs.p.aMember_8ADC47A7F55D9309CA87BD7B5D46D95D" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_EntityDomain_B9FF16D43A24467404DFBD7B5D46AF41" xlink:to="loc_livn_SNIAs.p.aMember_8ADC47A7F55D9309CA87BD7B5D46D95D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxAuthorityNameAxis" xlink:label="loc_us-gaap_IncomeTaxAuthorityNameAxis_1C38417F880B450C53F8BD7B5D46B22D" xlink:type="locator" />
    <link:definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_OtherCommitmentsTable_2F937CF1C4C53432A1C8BD7B5D3CD01A" xlink:to="loc_us-gaap_IncomeTaxAuthorityNameAxis_1C38417F880B450C53F8BD7B5D46B22D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxAuthorityNameDomain" xlink:label="loc_us-gaap_IncomeTaxAuthorityNameDomain_405F8D77A17D5A549364BD7B5D47C593_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeTaxAuthorityNameAxis_1C38417F880B450C53F8BD7B5D46B22D" xlink:to="loc_us-gaap_IncomeTaxAuthorityNameDomain_405F8D77A17D5A549364BD7B5D47C593_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeTaxAuthorityNameDomain" xlink:label="loc_us-gaap_IncomeTaxAuthorityNameDomain_405F8D77A17D5A549364BD7B5D47C593" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeTaxAuthorityNameAxis_1C38417F880B450C53F8BD7B5D46B22D" xlink:to="loc_us-gaap_IncomeTaxAuthorityNameDomain_405F8D77A17D5A549364BD7B5D47C593" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_RegionalInternalRevenueOfficeofLombardyMember" xlink:label="loc_livn_RegionalInternalRevenueOfficeofLombardyMember_918F25E56F2F19289DB2BD7B5D47DC3C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeTaxAuthorityNameDomain_405F8D77A17D5A549364BD7B5D47C593" xlink:to="loc_livn_RegionalInternalRevenueOfficeofLombardyMember_918F25E56F2F19289DB2BD7B5D47DC3C" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_LossContingencyNumberofObservedNonConformities" xlink:label="loc_livn_LossContingencyNumberofObservedNonConformities_EBD15A34DE45FFC391FABD7B5D471C79" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_CE1BB4237C1DC3F47F9CBD7B5D47EF4F" xlink:to="loc_livn_LossContingencyNumberofObservedNonConformities_EBD15A34DE45FFC391FABD7B5D471C79" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_ProductRemediationNet" xlink:label="loc_livn_ProductRemediationNet_692F0571C23911B40369BD7B5D471180" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_CE1BB4237C1DC3F47F9CBD7B5D47EF4F" xlink:to="loc_livn_ProductRemediationNet_692F0571C23911B40369BD7B5D471180" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LitigationSettlementAmountAwardedToOtherParty" xlink:label="loc_us-gaap_LitigationSettlementAmountAwardedToOtherParty_8D7DE111159455036C5DBD7B5D48070D" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_CE1BB4237C1DC3F47F9CBD7B5D47EF4F" xlink:to="loc_us-gaap_LitigationSettlementAmountAwardedToOtherParty_8D7DE111159455036C5DBD7B5D48070D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PaymentsForLegalSettlements" xlink:label="loc_us-gaap_PaymentsForLegalSettlements_5CB6BB9DB48EBFB85D7EBD7B5D482B78" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_CE1BB4237C1DC3F47F9CBD7B5D47EF4F" xlink:to="loc_us-gaap_PaymentsForLegalSettlements_5CB6BB9DB48EBFB85D7EBD7B5D482B78" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyPendingClaimsNumber" xlink:label="loc_us-gaap_LossContingencyPendingClaimsNumber_33720A02B7214D2C4B16BD7B5D480138" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_CE1BB4237C1DC3F47F9CBD7B5D47EF4F" xlink:to="loc_us-gaap_LossContingencyPendingClaimsNumber_33720A02B7214D2C4B16BD7B5D480138" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyAccrualAtCarryingValue" xlink:label="loc_us-gaap_LossContingencyAccrualAtCarryingValue_1C142591EF95649BC667BD7B5D499F14" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_CE1BB4237C1DC3F47F9CBD7B5D47EF4F" xlink:to="loc_us-gaap_LossContingencyAccrualAtCarryingValue_1C142591EF95649BC667BD7B5D499F14" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyDamagesSoughtValue" xlink:label="loc_us-gaap_LossContingencyDamagesSoughtValue_7549C6319C8A647D9F31BD7B5D49D184" xlink:type="locator" />
    <link:definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_CE1BB4237C1DC3F47F9CBD7B5D47EF4F" xlink:to="loc_us-gaap_LossContingencyDamagesSoughtValue_7549C6319C8A647D9F31BD7B5D49D184" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_ReimbursedLegalFees" xlink:label="loc_livn_ReimbursedLegalFees_385504E3D7CF1BA69E47BD7B5D49324B" xlink:type="locator" />
    <link:definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_CE1BB4237C1DC3F47F9CBD7B5D47EF4F" xlink:to="loc_livn_ReimbursedLegalFees_385504E3D7CF1BA69E47BD7B5D49324B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyEstimateOfPossibleLoss" xlink:label="loc_us-gaap_LossContingencyEstimateOfPossibleLoss_E53331F9CBCA4CF410FABD7B5D4AD1E3" xlink:type="locator" />
    <link:definitionArc order="9" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_CE1BB4237C1DC3F47F9CBD7B5D47EF4F" xlink:to="loc_us-gaap_LossContingencyEstimateOfPossibleLoss_E53331F9CBCA4CF410FABD7B5D4AD1E3" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_IncomeTaxExaminationOperatingLossesUnderDispute" xlink:label="loc_livn_IncomeTaxExaminationOperatingLossesUnderDispute_1F917B45165232D875A8BD7B5D4AC8E2" xlink:type="locator" />
    <link:definitionArc order="10" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_CE1BB4237C1DC3F47F9CBD7B5D47EF4F" xlink:to="loc_livn_IncomeTaxExaminationOperatingLossesUnderDispute_1F917B45165232D875A8BD7B5D4AC8E2" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_IncomeTaxExaminationNumberofInstallments" xlink:label="loc_livn_IncomeTaxExaminationNumberofInstallments_4A83BC2E3DEBA6202098BD7B5D4A1095" xlink:type="locator" />
    <link:definitionArc order="11" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_CE1BB4237C1DC3F47F9CBD7B5D47EF4F" xlink:to="loc_livn_IncomeTaxExaminationNumberofInstallments_4A83BC2E3DEBA6202098BD7B5D4A1095" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_LossContingencyNumberofAssessments" xlink:label="loc_livn_LossContingencyNumberofAssessments_B918ABB87013E8B5C3B0BD7B5D4A8D0B" xlink:type="locator" />
    <link:definitionArc order="12" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_CE1BB4237C1DC3F47F9CBD7B5D47EF4F" xlink:to="loc_livn_LossContingencyNumberofAssessments_B918ABB87013E8B5C3B0BD7B5D4A8D0B" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_IncomeTaxExaminationApplicationPendingApprovalPaymentsforLegalSettlements" xlink:label="loc_livn_IncomeTaxExaminationApplicationPendingApprovalPaymentsforLegalSettlements_6D8DA29D2A5B2CAECD90BD7B5D4B7C84" xlink:type="locator" />
    <link:definitionArc order="13" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_CE1BB4237C1DC3F47F9CBD7B5D47EF4F" xlink:to="loc_livn_IncomeTaxExaminationApplicationPendingApprovalPaymentsforLegalSettlements_6D8DA29D2A5B2CAECD90BD7B5D4B7C84" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsReserves" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsReserves_B64A1FCD29006113C04FBD7B5D4B8255" xlink:type="locator" />
    <link:definitionArc order="14" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_CE1BB4237C1DC3F47F9CBD7B5D47EF4F" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsReserves_B64A1FCD29006113C04FBD7B5D4B8255" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/CommitmentsAndContingenciesScheduleOfProductLiabilityDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingenciesLineItems" xlink:label="loc_us-gaap_LossContingenciesLineItems_4F898D795730519BADBFBCD6E4C249AB" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingenciesTable" xlink:label="loc_us-gaap_LossContingenciesTable_CA2ABF1668537DCF4CCFBCD6E4C16AC2" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_LossContingenciesLineItems_4F898D795730519BADBFBCD6E4C249AB" xlink:to="loc_us-gaap_LossContingenciesTable_CA2ABF1668537DCF4CCFBCD6E4C16AC2" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_LitigationCaseAxis" xlink:label="loc_srt_LitigationCaseAxis_AFCA14B6B6C12D65E759BCD6E4C285EA" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_LossContingenciesTable_CA2ABF1668537DCF4CCFBCD6E4C16AC2" xlink:to="loc_srt_LitigationCaseAxis_AFCA14B6B6C12D65E759BCD6E4C285EA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="loc_srt_LitigationCaseTypeDomain_EF9A605E3AE2B651F972BCD6E4C26223_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_LitigationCaseAxis_AFCA14B6B6C12D65E759BCD6E4C285EA" xlink:to="loc_srt_LitigationCaseTypeDomain_EF9A605E3AE2B651F972BCD6E4C26223_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="loc_srt_LitigationCaseTypeDomain_EF9A605E3AE2B651F972BCD6E4C26223" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_LitigationCaseAxis_AFCA14B6B6C12D65E759BCD6E4C285EA" xlink:to="loc_srt_LitigationCaseTypeDomain_EF9A605E3AE2B651F972BCD6E4C26223" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_ProductLiabilityMember" xlink:label="loc_livn_ProductLiabilityMember_16F58DB1A4066152C9B3BCD6E4C280AD" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_LitigationCaseTypeDomain_EF9A605E3AE2B651F972BCD6E4C26223" xlink:to="loc_livn_ProductLiabilityMember_16F58DB1A4066152C9B3BCD6E4C280AD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyAccrualRollForward" xlink:label="loc_us-gaap_LossContingencyAccrualRollForward_F2242843441FD63E441BBCD6E4C3EC96" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingenciesLineItems_4F898D795730519BADBFBCD6E4C249AB" xlink:to="loc_us-gaap_LossContingencyAccrualRollForward_F2242843441FD63E441BBCD6E4C3EC96" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyAccrualAtCarryingValue" xlink:label="loc_us-gaap_LossContingencyAccrualAtCarryingValue_5C2168432589752D84C2BCD6E4C3EA0D" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingencyAccrualRollForward_F2242843441FD63E441BBCD6E4C3EC96" xlink:to="loc_us-gaap_LossContingencyAccrualAtCarryingValue_5C2168432589752D84C2BCD6E4C3EA0D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyAccrualPayments" xlink:label="loc_us-gaap_LossContingencyAccrualPayments_6D3E4E848106F3A9A508BCD6E4C3D175" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingencyAccrualRollForward_F2242843441FD63E441BBCD6E4C3EC96" xlink:to="loc_us-gaap_LossContingencyAccrualPayments_6D3E4E848106F3A9A508BCD6E4C3D175" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_LossContingencyAccrualForeignCurrencyAdjustments" xlink:label="loc_livn_LossContingencyAccrualForeignCurrencyAdjustments_BC59A39860E1111F0AABBCD6E4C32E89" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingencyAccrualRollForward_F2242843441FD63E441BBCD6E4C3EC96" xlink:to="loc_livn_LossContingencyAccrualForeignCurrencyAdjustments_BC59A39860E1111F0AABBCD6E4C32E89" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyAccrualCarryingValueCurrent" xlink:label="loc_us-gaap_LossContingencyAccrualCarryingValueCurrent_D6AE964DBB5833DE95E0BCD6E4C430B6" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingencyAccrualRollForward_F2242843441FD63E441BBCD6E4C3EC96" xlink:to="loc_us-gaap_LossContingencyAccrualCarryingValueCurrent_D6AE964DBB5833DE95E0BCD6E4C430B6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyAccrualCarryingValueNoncurrent" xlink:label="loc_us-gaap_LossContingencyAccrualCarryingValueNoncurrent_61B98F49CF38EF35CCB3BCD6E4C45961" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LossContingencyAccrualRollForward_F2242843441FD63E441BBCD6E4C3EC96" xlink:to="loc_us-gaap_LossContingencyAccrualCarryingValueNoncurrent_61B98F49CF38EF35CCB3BCD6E4C45961" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/CommitmentsAndContingenciesTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/CondensedConsolidatedBalanceSheets" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/CondensedConsolidatedBalanceSheetsParenthetical" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/CondensedConsolidatedStatementsOfCashFlows" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/CondensedConsolidatedStatementsOfComprehensiveIncomeLoss" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/CondensedConsolidatedStatementsOfIncomeLoss" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/CoverPage" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagement" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementAmountOfGainLossRecognizedInOciAndIncomeStatementDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossLineItems" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_90E8253F599A964570AFBCD6E4E7899D" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_1A0AF99D2D34ABF83A58BCD6E4E41241" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_90E8253F599A964570AFBCD6E4E7899D" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_1A0AF99D2D34ABF83A58BCD6E4E41241" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_B801204062301FA990E9BCD6E4E43BE1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_1A0AF99D2D34ABF83A58BCD6E4E41241" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_B801204062301FA990E9BCD6E4E43BE1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_HedgingRelationshipDomain" xlink:label="loc_us-gaap_HedgingRelationshipDomain_7E940B202DC4AA1F279DBCD6E4E57D19_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_B801204062301FA990E9BCD6E4E43BE1" xlink:to="loc_us-gaap_HedgingRelationshipDomain_7E940B202DC4AA1F279DBCD6E4E57D19_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_HedgingRelationshipDomain" xlink:label="loc_us-gaap_HedgingRelationshipDomain_7E940B202DC4AA1F279DBCD6E4E57D19" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_B801204062301FA990E9BCD6E4E43BE1" xlink:to="loc_us-gaap_HedgingRelationshipDomain_7E940B202DC4AA1F279DBCD6E4E57D19" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashFlowHedgingMember" xlink:label="loc_us-gaap_CashFlowHedgingMember_6DBAB2791DA102764A75BCD6E4E56D16" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingRelationshipDomain_7E940B202DC4AA1F279DBCD6E4E57D19" xlink:to="loc_us-gaap_CashFlowHedgingMember_6DBAB2791DA102764A75BCD6E4E56D16" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_1401A37374245724B738BCD6E4E5BCD5" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_1A0AF99D2D34ABF83A58BCD6E4E41241" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_1401A37374245724B738BCD6E4E5BCD5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_7F2A1F1767F6CD09102DBCD6E4E598F7_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_1401A37374245724B738BCD6E4E5BCD5" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_7F2A1F1767F6CD09102DBCD6E4E598F7_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_7F2A1F1767F6CD09102DBCD6E4E598F7" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_1401A37374245724B738BCD6E4E5BCD5" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_7F2A1F1767F6CD09102DBCD6E4E598F7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ForeignExchangeContractMember" xlink:label="loc_us-gaap_ForeignExchangeContractMember_406777F706C755378447BCD6E4E67C1E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_7F2A1F1767F6CD09102DBCD6E4E598F7" xlink:to="loc_us-gaap_ForeignExchangeContractMember_406777F706C755378447BCD6E4E67C1E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InterestRateSwapMember" xlink:label="loc_us-gaap_InterestRateSwapMember_6C530A2DF75F408FEA94BCD6E4E63D61" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_7F2A1F1767F6CD09102DBCD6E4E598F7" xlink:to="loc_us-gaap_InterestRateSwapMember_6C530A2DF75F408FEA94BCD6E4E63D61" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_67B8722F5AA1ECA27C29BCD6E4E66752" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipByIncomeStatementLocationByDerivativeInstrumentRiskTable_1A0AF99D2D34ABF83A58BCD6E4E41241" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_67B8722F5AA1ECA27C29BCD6E4E66752" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_557E6543158642DA97ECBCD6E4E69773_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_67B8722F5AA1ECA27C29BCD6E4E66752" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_557E6543158642DA97ECBCD6E4E69773_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_557E6543158642DA97ECBCD6E4E69773" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_67B8722F5AA1ECA27C29BCD6E4E66752" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_557E6543158642DA97ECBCD6E4E69773" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_ForeignExchangeandOtherMember" xlink:label="loc_livn_ForeignExchangeandOtherMember_60E5AC7F1CB540EC8786BCD6E4E63BED" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_557E6543158642DA97ECBCD6E4E69773" xlink:to="loc_livn_ForeignExchangeandOtherMember_60E5AC7F1CB540EC8786BCD6E4E63BED" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpensesMember" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_D37BCD37C5E3079351A3BCD6E4E738B1" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_557E6543158642DA97ECBCD6E4E69773" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_D37BCD37C5E3079351A3BCD6E4E738B1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InterestExpenseMember" xlink:label="loc_us-gaap_InterestExpenseMember_8F8F384499532EBE0772BCD6E4E79F3F" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_557E6543158642DA97ECBCD6E4E69773" xlink:to="loc_us-gaap_InterestExpenseMember_8F8F384499532EBE0772BCD6E4E79F3F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAndTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAndTax_FD58AB5C8194809A78A8BCD6E4E745AE" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_90E8253F599A964570AFBCD6E4E7899D" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossBeforeReclassificationAndTax_FD58AB5C8194809A78A8BCD6E4E745AE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossReclassificationBeforeTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossReclassificationBeforeTax_4ADF995734B3097D5411BCD6E4E7F743" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossLineItems_90E8253F599A964570AFBCD6E4E7899D" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossCashFlowHedgeGainLossReclassificationBeforeTax_4ADF995734B3097D5411BCD6E4E7F743" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementDerivativeNotionalAmountsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeLineItems" xlink:label="loc_us-gaap_DerivativeLineItems_97EF78CC2C352C0DDAA1BCD6E4F06F1B" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeTable" xlink:label="loc_us-gaap_DerivativeTable_5D1083133A7C282A6C31BCD6E4EC9E5F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativeLineItems_97EF78CC2C352C0DDAA1BCD6E4F06F1B" xlink:to="loc_us-gaap_DerivativeTable_5D1083133A7C282A6C31BCD6E4EC9E5F" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_HedgingDesignationAxis" xlink:label="loc_us-gaap_HedgingDesignationAxis_1E5930EC602D01F35288BCD6E4EC760B" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_5D1083133A7C282A6C31BCD6E4EC9E5F" xlink:to="loc_us-gaap_HedgingDesignationAxis_1E5930EC602D01F35288BCD6E4EC760B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="loc_us-gaap_HedgingDesignationDomain_73E263355667CE8BA278BCD6E4EC8BDB_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_HedgingDesignationAxis_1E5930EC602D01F35288BCD6E4EC760B" xlink:to="loc_us-gaap_HedgingDesignationDomain_73E263355667CE8BA278BCD6E4EC8BDB_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="loc_us-gaap_HedgingDesignationDomain_73E263355667CE8BA278BCD6E4EC8BDB" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_HedgingDesignationAxis_1E5930EC602D01F35288BCD6E4EC760B" xlink:to="loc_us-gaap_HedgingDesignationDomain_73E263355667CE8BA278BCD6E4EC8BDB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DesignatedAsHedgingInstrumentMember" xlink:label="loc_us-gaap_DesignatedAsHedgingInstrumentMember_3BA384C0017DF2848E59BCD6E4ED1222" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_73E263355667CE8BA278BCD6E4EC8BDB" xlink:to="loc_us-gaap_DesignatedAsHedgingInstrumentMember_3BA384C0017DF2848E59BCD6E4ED1222" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis" xlink:label="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_23EB55319CE7493C3FFEBCD6E4EDFEB1" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_5D1083133A7C282A6C31BCD6E4EC9E5F" xlink:to="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_23EB55319CE7493C3FFEBCD6E4EDFEB1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_HedgingRelationshipDomain" xlink:label="loc_us-gaap_HedgingRelationshipDomain_35231A9A71C181080996BCD6E4ED5BC8_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_23EB55319CE7493C3FFEBCD6E4EDFEB1" xlink:to="loc_us-gaap_HedgingRelationshipDomain_35231A9A71C181080996BCD6E4ED5BC8_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_HedgingRelationshipDomain" xlink:label="loc_us-gaap_HedgingRelationshipDomain_35231A9A71C181080996BCD6E4ED5BC8" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentsGainLossByHedgingRelationshipAxis_23EB55319CE7493C3FFEBCD6E4EDFEB1" xlink:to="loc_us-gaap_HedgingRelationshipDomain_35231A9A71C181080996BCD6E4ED5BC8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashFlowHedgingMember" xlink:label="loc_us-gaap_CashFlowHedgingMember_83F48BE64AB27671EB31BCD6E4EDB1C0" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingRelationshipDomain_35231A9A71C181080996BCD6E4ED5BC8" xlink:to="loc_us-gaap_CashFlowHedgingMember_83F48BE64AB27671EB31BCD6E4EDB1C0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_51BC8E6A9F3EC3ABF2C2BCD6E4EE3DD3" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_5D1083133A7C282A6C31BCD6E4EC9E5F" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_51BC8E6A9F3EC3ABF2C2BCD6E4EE3DD3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_337586BBF87441857C54BCD6E4EE47D8_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_51BC8E6A9F3EC3ABF2C2BCD6E4EE3DD3" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_337586BBF87441857C54BCD6E4EE47D8_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_337586BBF87441857C54BCD6E4EE47D8" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_51BC8E6A9F3EC3ABF2C2BCD6E4EE3DD3" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_337586BBF87441857C54BCD6E4EE47D8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ForeignExchangeContractMember" xlink:label="loc_us-gaap_ForeignExchangeContractMember_D6D7CD2A908E1F7B89D3BCD6E4EEA2CA" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_337586BBF87441857C54BCD6E4EE47D8" xlink:to="loc_us-gaap_ForeignExchangeContractMember_D6D7CD2A908E1F7B89D3BCD6E4EEA2CA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InterestRateSwapMember" xlink:label="loc_us-gaap_InterestRateSwapMember_AA57221778E727D6BA9DBCD6E4EE0EB6" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_337586BBF87441857C54BCD6E4EE47D8" xlink:to="loc_us-gaap_InterestRateSwapMember_AA57221778E727D6BA9DBCD6E4EE0EB6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_CurrencyAxis" xlink:label="loc_srt_CurrencyAxis_7E048022691F52033699BCD6E4EF4132" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_5D1083133A7C282A6C31BCD6E4EC9E5F" xlink:to="loc_srt_CurrencyAxis_7E048022691F52033699BCD6E4EF4132" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/currency/2019/currency-2019-01-31.xsd#currency_AllCurrenciesDomain" xlink:label="loc_currency_AllCurrenciesDomain_B06F4090BDF435045386BCD6E4EF5471_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_CurrencyAxis_7E048022691F52033699BCD6E4EF4132" xlink:to="loc_currency_AllCurrenciesDomain_B06F4090BDF435045386BCD6E4EF5471_default" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/currency/2019/currency-2019-01-31.xsd#currency_AllCurrenciesDomain" xlink:label="loc_currency_AllCurrenciesDomain_B06F4090BDF435045386BCD6E4EF5471" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_CurrencyAxis_7E048022691F52033699BCD6E4EF4132" xlink:to="loc_currency_AllCurrenciesDomain_B06F4090BDF435045386BCD6E4EF5471" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/currency/2019/currency-2019-01-31.xsd#currency_GBP" xlink:label="loc_currency_GBP_ACA25D2ABEE840120764BCD6E4EF59B0" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_currency_AllCurrenciesDomain_B06F4090BDF435045386BCD6E4EF5471" xlink:to="loc_currency_GBP_ACA25D2ABEE840120764BCD6E4EF59B0" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/currency/2019/currency-2019-01-31.xsd#currency_JPY" xlink:label="loc_currency_JPY_0974407C9A531C118180BCD6E4EF88C6" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_currency_AllCurrenciesDomain_B06F4090BDF435045386BCD6E4EF5471" xlink:to="loc_currency_JPY_0974407C9A531C118180BCD6E4EF88C6" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/currency/2019/currency-2019-01-31.xsd#currency_EUR" xlink:label="loc_currency_EUR_22ADCC4C4F19FDD60BFCBCD6E4F0E682" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_currency_AllCurrenciesDomain_B06F4090BDF435045386BCD6E4EF5471" xlink:to="loc_currency_EUR_22ADCC4C4F19FDD60BFCBCD6E4F0E682" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeNotionalAmount" xlink:label="loc_us-gaap_DerivativeNotionalAmount_4AF030F99A712ADE41E0BCD6E4F045A9" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_97EF78CC2C352C0DDAA1BCD6E4F06F1B" xlink:to="loc_us-gaap_DerivativeNotionalAmount_4AF030F99A712ADE41E0BCD6E4F045A9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossDerivativeExcludedComponentIncreaseDecreaseBeforeAdjustmentsAfterTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossDerivativeExcludedComponentIncreaseDecreaseBeforeAdjustmentsAfterTax_B1611D78272EA89A89B8BCD6E4F024FD" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_97EF78CC2C352C0DDAA1BCD6E4F06F1B" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossDerivativeExcludedComponentIncreaseDecreaseBeforeAdjustmentsAfterTax_B1611D78272EA89A89B8BCD6E4F024FD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashFlowHedgeGainLossToBeReclassifiedWithinTwelveMonths" xlink:label="loc_us-gaap_CashFlowHedgeGainLossToBeReclassifiedWithinTwelveMonths_62558A3F4C5243CD91FBBCD6E4F0B697" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_97EF78CC2C352C0DDAA1BCD6E4F06F1B" xlink:to="loc_us-gaap_CashFlowHedgeGainLossToBeReclassifiedWithinTwelveMonths_62558A3F4C5243CD91FBBCD6E4F0B697" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementFairValueOfDerivativeInstrumentsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativesFairValueLineItems" xlink:label="loc_us-gaap_DerivativesFairValueLineItems_D0D56A801253E06AD2F7BCD6E4E0601F" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable" xlink:label="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_A6D3CA451D56AE984AD9BCD6E4DC6419" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_D0D56A801253E06AD2F7BCD6E4E0601F" xlink:to="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_A6D3CA451D56AE984AD9BCD6E4DC6419" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_HedgingDesignationAxis" xlink:label="loc_us-gaap_HedgingDesignationAxis_8C85591D102E474189EDBCD6E4DDEA5A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_A6D3CA451D56AE984AD9BCD6E4DC6419" xlink:to="loc_us-gaap_HedgingDesignationAxis_8C85591D102E474189EDBCD6E4DDEA5A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="loc_us-gaap_HedgingDesignationDomain_0F0D771C8960F8F7528ABCD6E4DDA113_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_HedgingDesignationAxis_8C85591D102E474189EDBCD6E4DDEA5A" xlink:to="loc_us-gaap_HedgingDesignationDomain_0F0D771C8960F8F7528ABCD6E4DDA113_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="loc_us-gaap_HedgingDesignationDomain_0F0D771C8960F8F7528ABCD6E4DDA113" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_HedgingDesignationAxis_8C85591D102E474189EDBCD6E4DDEA5A" xlink:to="loc_us-gaap_HedgingDesignationDomain_0F0D771C8960F8F7528ABCD6E4DDA113" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DesignatedAsHedgingInstrumentMember" xlink:label="loc_us-gaap_DesignatedAsHedgingInstrumentMember_343F053EF6F9AA246F54BCD6E4DD006D" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_0F0D771C8960F8F7528ABCD6E4DDA113" xlink:to="loc_us-gaap_DesignatedAsHedgingInstrumentMember_343F053EF6F9AA246F54BCD6E4DD006D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NondesignatedMember" xlink:label="loc_us-gaap_NondesignatedMember_183F25F2DAB90DBCB846BCD6E4DD7B0E" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_0F0D771C8960F8F7528ABCD6E4DDA113" xlink:to="loc_us-gaap_NondesignatedMember_183F25F2DAB90DBCB846BCD6E4DD7B0E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BalanceSheetLocationAxis" xlink:label="loc_us-gaap_BalanceSheetLocationAxis_292FDF0A35DDCD3C8AF1BCD6E4DE73E9" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_A6D3CA451D56AE984AD9BCD6E4DC6419" xlink:to="loc_us-gaap_BalanceSheetLocationAxis_292FDF0A35DDCD3C8AF1BCD6E4DE73E9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BalanceSheetLocationDomain" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_E012CE64335CD3349076BCD6E4DE73FF_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_292FDF0A35DDCD3C8AF1BCD6E4DE73E9" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_E012CE64335CD3349076BCD6E4DE73FF_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BalanceSheetLocationDomain" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_E012CE64335CD3349076BCD6E4DE73FF" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_292FDF0A35DDCD3C8AF1BCD6E4DE73E9" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_E012CE64335CD3349076BCD6E4DE73FF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PrepaidExpensesAndOtherCurrentAssetsMember" xlink:label="loc_us-gaap_PrepaidExpensesAndOtherCurrentAssetsMember_940B54AACD8553625995BCD6E4DE89B3" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_E012CE64335CD3349076BCD6E4DE73FF" xlink:to="loc_us-gaap_PrepaidExpensesAndOtherCurrentAssetsMember_940B54AACD8553625995BCD6E4DE89B3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccruedLiabilitiesMember" xlink:label="loc_us-gaap_AccruedLiabilitiesMember_6677A587457D392A8C98BCD6E4DE19AE" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_E012CE64335CD3349076BCD6E4DE73FF" xlink:to="loc_us-gaap_AccruedLiabilitiesMember_6677A587457D392A8C98BCD6E4DE19AE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherNoncurrentLiabilitiesMember" xlink:label="loc_us-gaap_OtherNoncurrentLiabilitiesMember_9438EC4F47D7A87B6B1DBCD6E4DE1F97" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_E012CE64335CD3349076BCD6E4DE73FF" xlink:to="loc_us-gaap_OtherNoncurrentLiabilitiesMember_9438EC4F47D7A87B6B1DBCD6E4DE1F97" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_E2BBE5B00C04A250C555BCD6E4DF15AA" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValuesDerivativesBalanceSheetLocationByDerivativeContractTypeByHedgingDesignationTable_A6D3CA451D56AE984AD9BCD6E4DC6419" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_E2BBE5B00C04A250C555BCD6E4DF15AA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_E00D1C35CC9E57C9B439BCD6E4DFD93A_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_E2BBE5B00C04A250C555BCD6E4DF15AA" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_E00D1C35CC9E57C9B439BCD6E4DFD93A_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_E00D1C35CC9E57C9B439BCD6E4DFD93A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_E2BBE5B00C04A250C555BCD6E4DF15AA" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_E00D1C35CC9E57C9B439BCD6E4DFD93A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InterestRateContractMember" xlink:label="loc_us-gaap_InterestRateContractMember_E2B3EE2013820D669FD3BCD6E4DF1A60" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_E00D1C35CC9E57C9B439BCD6E4DFD93A" xlink:to="loc_us-gaap_InterestRateContractMember_E2B3EE2013820D669FD3BCD6E4DF1A60" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ForeignExchangeContractMember" xlink:label="loc_us-gaap_ForeignExchangeContractMember_D2B3A8FE9D64E433711EBCD6E4DFBC85" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_E00D1C35CC9E57C9B439BCD6E4DFD93A" xlink:to="loc_us-gaap_ForeignExchangeContractMember_D2B3A8FE9D64E433711EBCD6E4DFBC85" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeAsset" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeAsset_7DB060AC34763C16B67FBCD6E4E06EE5" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_D0D56A801253E06AD2F7BCD6E4E0601F" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeAsset_7DB060AC34763C16B67FBCD6E4E06EE5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeLiability" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_6B118CB491E2F0EDAF2BBCD6E4E0E0C0" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativesFairValueLineItems_D0D56A801253E06AD2F7BCD6E4E0601F" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_6B118CB491E2F0EDAF2BBCD6E4E0E0C0" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeLineItems" xlink:label="loc_us-gaap_DerivativeLineItems_FF5D332F38C815D1E487BCD6E4F7F824" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeTable" xlink:label="loc_us-gaap_DerivativeTable_02FC1ECFBD0A5042F9D0BCD6E4F4E9D1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DerivativeLineItems_FF5D332F38C815D1E487BCD6E4F7F824" xlink:to="loc_us-gaap_DerivativeTable_02FC1ECFBD0A5042F9D0BCD6E4F4E9D1" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_2D488D11E579EA867F91BCD6E4F4EFB5" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_02FC1ECFBD0A5042F9D0BCD6E4F4E9D1" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_2D488D11E579EA867F91BCD6E4F4EFB5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_8E299A4F8FA506A5ED93BCD6E4F51DDF_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_2D488D11E579EA867F91BCD6E4F4EFB5" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_8E299A4F8FA506A5ED93BCD6E4F51DDF_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_8E299A4F8FA506A5ED93BCD6E4F51DDF" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_2D488D11E579EA867F91BCD6E4F4EFB5" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_8E299A4F8FA506A5ED93BCD6E4F51DDF" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_ForeignExchangeandOtherMember" xlink:label="loc_livn_ForeignExchangeandOtherMember_B909A1F4E2A4A1B48440BCD6E4F5ED98" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_8E299A4F8FA506A5ED93BCD6E4F51DDF" xlink:to="loc_livn_ForeignExchangeandOtherMember_B909A1F4E2A4A1B48440BCD6E4F5ED98" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_HedgingDesignationAxis" xlink:label="loc_us-gaap_HedgingDesignationAxis_02E50807F935E11FE923BCD6E4F55E09" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_02FC1ECFBD0A5042F9D0BCD6E4F4E9D1" xlink:to="loc_us-gaap_HedgingDesignationAxis_02E50807F935E11FE923BCD6E4F55E09" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="loc_us-gaap_HedgingDesignationDomain_F9F5BA0AE6FCE7B3FA0FBCD6E4F59607_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_HedgingDesignationAxis_02E50807F935E11FE923BCD6E4F55E09" xlink:to="loc_us-gaap_HedgingDesignationDomain_F9F5BA0AE6FCE7B3FA0FBCD6E4F59607_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="loc_us-gaap_HedgingDesignationDomain_F9F5BA0AE6FCE7B3FA0FBCD6E4F59607" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_HedgingDesignationAxis_02E50807F935E11FE923BCD6E4F55E09" xlink:to="loc_us-gaap_HedgingDesignationDomain_F9F5BA0AE6FCE7B3FA0FBCD6E4F59607" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NondesignatedMember" xlink:label="loc_us-gaap_NondesignatedMember_14EE0DD5BEFE3C07646ABCD6E4F6A928" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_F9F5BA0AE6FCE7B3FA0FBCD6E4F59607" xlink:to="loc_us-gaap_NondesignatedMember_14EE0DD5BEFE3C07646ABCD6E4F6A928" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_3E9B117EEF703CB8B3B4BCD6E4F6952C" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DerivativeTable_02FC1ECFBD0A5042F9D0BCD6E4F4E9D1" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_3E9B117EEF703CB8B3B4BCD6E4F6952C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_FCDF72299C4FB34D4F83BCD6E4F65961_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_3E9B117EEF703CB8B3B4BCD6E4F6952C" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_FCDF72299C4FB34D4F83BCD6E4F65961_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_FCDF72299C4FB34D4F83BCD6E4F65961" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_3E9B117EEF703CB8B3B4BCD6E4F6952C" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_FCDF72299C4FB34D4F83BCD6E4F65961" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ForeignExchangeContractMember" xlink:label="loc_us-gaap_ForeignExchangeContractMember_21A5B2A35D86B212986EBCD6E4F6C3A3" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_FCDF72299C4FB34D4F83BCD6E4F65961" xlink:to="loc_us-gaap_ForeignExchangeContractMember_21A5B2A35D86B212986EBCD6E4F6C3A3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeNotionalAmount" xlink:label="loc_us-gaap_DerivativeNotionalAmount_2A130C2A13CC61BAF8F1BCD6E4F76F28" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_FF5D332F38C815D1E487BCD6E4F7F824" xlink:to="loc_us-gaap_DerivativeNotionalAmount_2A130C2A13CC61BAF8F1BCD6E4F76F28" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeGainLossOnDerivativeNet" xlink:label="loc_us-gaap_DerivativeGainLossOnDerivativeNet_08FDDD8AB6BEF05553E1BCD6E4F7C0E7" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeLineItems_FF5D332F38C815D1E487BCD6E4F7F824" xlink:to="loc_us-gaap_DerivativeGainLossOnDerivativeNet_08FDDD8AB6BEF05553E1BCD6E4F7C0E7" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/DerivativesAndRiskManagementTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/DiscontinuedOperations" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/DiscontinuedOperationsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_63F529CD5E6E0572E643BE84BD319F84" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_242636DBC1BBFF4ED07ABE84BD30F16F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_63F529CD5E6E0572E643BE84BD319F84" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_242636DBC1BBFF4ED07ABE84BD30F16F" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_5980483B3EDA027A6925BE84BD3016D3" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_242636DBC1BBFF4ED07ABE84BD30F16F" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_5980483B3EDA027A6925BE84BD3016D3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_B172DAF5DADE5A3C7273BE84BD30E362_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_5980483B3EDA027A6925BE84BD3016D3" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_B172DAF5DADE5A3C7273BE84BD30E362_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_B172DAF5DADE5A3C7273BE84BD30E362" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_5980483B3EDA027A6925BE84BD3016D3" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_B172DAF5DADE5A3C7273BE84BD30E362" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_CRMBusinessFranchiseMember" xlink:label="loc_livn_CRMBusinessFranchiseMember_4908D69B46F70D0CACE2BE84BD31C407" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_B172DAF5DADE5A3C7273BE84BD30E362" xlink:to="loc_livn_CRMBusinessFranchiseMember_4908D69B46F70D0CACE2BE84BD31C407" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementOperatingActivitiesSegmentAxis" xlink:label="loc_us-gaap_StatementOperatingActivitiesSegmentAxis_0E6C20111778B9A4B74ABE84BD31261D" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_242636DBC1BBFF4ED07ABE84BD30F16F" xlink:to="loc_us-gaap_StatementOperatingActivitiesSegmentAxis_0E6C20111778B9A4B74ABE84BD31261D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentOperatingActivitiesDomain" xlink:label="loc_us-gaap_SegmentOperatingActivitiesDomain_6BB505023E0C7ABE04DABE84BD3174AC_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementOperatingActivitiesSegmentAxis_0E6C20111778B9A4B74ABE84BD31261D" xlink:to="loc_us-gaap_SegmentOperatingActivitiesDomain_6BB505023E0C7ABE04DABE84BD3174AC_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentOperatingActivitiesDomain" xlink:label="loc_us-gaap_SegmentOperatingActivitiesDomain_6BB505023E0C7ABE04DABE84BD3174AC" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementOperatingActivitiesSegmentAxis_0E6C20111778B9A4B74ABE84BD31261D" xlink:to="loc_us-gaap_SegmentOperatingActivitiesDomain_6BB505023E0C7ABE04DABE84BD3174AC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentDiscontinuedOperationsMember" xlink:label="loc_us-gaap_SegmentDiscontinuedOperationsMember_79E0A36214FB1B9E0CF8BE84BD31A157" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentOperatingActivitiesDomain_6BB505023E0C7ABE04DABE84BD3174AC" xlink:to="loc_us-gaap_SegmentDiscontinuedOperationsMember_79E0A36214FB1B9E0CF8BE84BD31A157" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferred1" xlink:label="loc_us-gaap_BusinessCombinationConsiderationTransferred1_0043C8F8660F0E458FE3BE84BD32B624" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_63F529CD5E6E0572E643BE84BD319F84" xlink:to="loc_us-gaap_BusinessCombinationConsiderationTransferred1_0043C8F8660F0E458FE3BE84BD32B624" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_BusinessCombinationConsiderationTransferredCashTransferred" xlink:label="loc_livn_BusinessCombinationConsiderationTransferredCashTransferred_8C327DF9C025FC9507F6BE84BD320EB3" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_63F529CD5E6E0572E643BE84BD319F84" xlink:to="loc_livn_BusinessCombinationConsiderationTransferredCashTransferred_8C327DF9C025FC9507F6BE84BD320EB3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DiscontinuedOperationAmountOfAdjustmentToPriorPeriodGainLossOnDisposalBeforeIncomeTax" xlink:label="loc_us-gaap_DiscontinuedOperationAmountOfAdjustmentToPriorPeriodGainLossOnDisposalBeforeIncomeTax_14C34BE4ECC04D527D33BEB1F545C18B" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_63F529CD5E6E0572E643BE84BD319F84" xlink:to="loc_us-gaap_DiscontinuedOperationAmountOfAdjustmentToPriorPeriodGainLossOnDisposalBeforeIncomeTax_14C34BE4ECC04D527D33BEB1F545C18B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DiscontinuedOperationGainLossOnDisposalOfDiscontinuedOperationNetOfTax" xlink:label="loc_us-gaap_DiscontinuedOperationGainLossOnDisposalOfDiscontinuedOperationNetOfTax_AB016575F4AFA1EE4901BEB146DAE8AF" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_63F529CD5E6E0572E643BE84BD319F84" xlink:to="loc_us-gaap_DiscontinuedOperationGainLossOnDisposalOfDiscontinuedOperationNetOfTax_AB016575F4AFA1EE4901BEB146DAE8AF" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/DiscontinuedOperationsOperatingGainsAndLossesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_7512904E5ADEB8A0A32FC6C83AE5060C" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_7A087BB2E4D9851E5DE6C6C83AE2EBB9" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_7512904E5ADEB8A0A32FC6C83AE5060C" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_7A087BB2E4D9851E5DE6C6C83AE2EBB9" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis" xlink:label="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_D7C8B60E788EEB830178C6C83AE324F9" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_7A087BB2E4D9851E5DE6C6C83AE2EBB9" xlink:to="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_D7C8B60E788EEB830178C6C83AE324F9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_A751F414A4A743C1400AC6C83AE36062_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_D7C8B60E788EEB830178C6C83AE324F9" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_A751F414A4A743C1400AC6C83AE36062_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain" xlink:label="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_A751F414A4A743C1400AC6C83AE36062" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsAxis_D7C8B60E788EEB830178C6C83AE324F9" xlink:to="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_A751F414A4A743C1400AC6C83AE36062" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_CRMBusinessFranchiseMember" xlink:label="loc_livn_CRMBusinessFranchiseMember_260825C5E47623C490FCC6C83AE3DC02" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DisposalGroupsIncludingDiscontinuedOperationsNameDomain_A751F414A4A743C1400AC6C83AE36062" xlink:to="loc_livn_CRMBusinessFranchiseMember_260825C5E47623C490FCC6C83AE3DC02" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupClassificationAxis" xlink:label="loc_us-gaap_DisposalGroupClassificationAxis_43D94E043D72936BD352C6C83AE4F3DB" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsTable_7A087BB2E4D9851E5DE6C6C83AE2EBB9" xlink:to="loc_us-gaap_DisposalGroupClassificationAxis_43D94E043D72936BD352C6C83AE4F3DB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="loc_us-gaap_DisposalGroupClassificationDomain_55AE99A1AD257933C4AEC6C83AE4BD64_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DisposalGroupClassificationAxis_43D94E043D72936BD352C6C83AE4F3DB" xlink:to="loc_us-gaap_DisposalGroupClassificationDomain_55AE99A1AD257933C4AEC6C83AE4BD64_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupClassificationDomain" xlink:label="loc_us-gaap_DisposalGroupClassificationDomain_55AE99A1AD257933C4AEC6C83AE4BD64" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DisposalGroupClassificationAxis_43D94E043D72936BD352C6C83AE4F3DB" xlink:to="loc_us-gaap_DisposalGroupClassificationDomain_55AE99A1AD257933C4AEC6C83AE4BD64" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DiscontinuedOperationsHeldForSaleOrDisposedOfBySaleMember" xlink:label="loc_us-gaap_DiscontinuedOperationsHeldForSaleOrDisposedOfBySaleMember_A81CCA2AADB1419855AEC6C83AE55B7C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DisposalGroupClassificationDomain_55AE99A1AD257933C4AEC6C83AE4BD64" xlink:to="loc_us-gaap_DiscontinuedOperationsHeldForSaleOrDisposedOfBySaleMember_A81CCA2AADB1419855AEC6C83AE55B7C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DiscontinuedOperationGainLossFromDisposalOfDiscontinuedOperationBeforeIncomeTax" xlink:label="loc_us-gaap_DiscontinuedOperationGainLossFromDisposalOfDiscontinuedOperationBeforeIncomeTax_7D4D8B16AFB8FC4D609CC6C83AE50842" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_7512904E5ADEB8A0A32FC6C83AE5060C" xlink:to="loc_us-gaap_DiscontinuedOperationGainLossFromDisposalOfDiscontinuedOperationBeforeIncomeTax_7D4D8B16AFB8FC4D609CC6C83AE50842" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DisposalGroupIncludingDiscontinuedOperationOperatingIncomeLoss" xlink:label="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOperatingIncomeLoss_63708CF2D8E5657FD0E1C6C83AE5A208" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_7512904E5ADEB8A0A32FC6C83AE5060C" xlink:to="loc_us-gaap_DisposalGroupIncludingDiscontinuedOperationOperatingIncomeLoss_63708CF2D8E5657FD0E1C6C83AE5A208" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationDuringPhaseOutPeriodBeforeIncomeTax" xlink:label="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationDuringPhaseOutPeriodBeforeIncomeTax_0DA5E611C5AB4EC5C57CC6C83AE6F345" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_7512904E5ADEB8A0A32FC6C83AE5060C" xlink:to="loc_us-gaap_DiscontinuedOperationIncomeLossFromDiscontinuedOperationDuringPhaseOutPeriodBeforeIncomeTax_0DA5E611C5AB4EC5C57CC6C83AE6F345" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DiscontinuedOperationTaxEffectOfIncomeLossFromDiscontinuedOperationDuringPhaseOutPeriod" xlink:label="loc_us-gaap_DiscontinuedOperationTaxEffectOfIncomeLossFromDiscontinuedOperationDuringPhaseOutPeriod_D1E1C22C38429925A231C6C83AE61E5F" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_7512904E5ADEB8A0A32FC6C83AE5060C" xlink:to="loc_us-gaap_DiscontinuedOperationTaxEffectOfIncomeLossFromDiscontinuedOperationDuringPhaseOutPeriod_D1E1C22C38429925A231C6C83AE61E5F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity" xlink:label="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_AF93C1675174B4E7AA10C6C83AE63607" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementBalanceSheetAndAdditionalDisclosuresByDisposalGroupsIncludingDiscontinuedOperationsLineItems_7512904E5ADEB8A0A32FC6C83AE5060C" xlink:to="loc_us-gaap_IncomeLossFromDiscontinuedOperationsNetOfTaxAttributableToReportingEntity_AF93C1675174B4E7AA10C6C83AE63607" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/DiscontinuedOperationsTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/EarningsPerShare" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/EarningsPerShareNarrativeOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_53E8E33EFF29BFD9CA36BCD6E4A32E45" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_9CEB67838712D0ECD023BCD6E4A27502" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_53E8E33EFF29BFD9CA36BCD6E4A32E45" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_9CEB67838712D0ECD023BCD6E4A27502" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_86C7F2697D5B13BA73BCBCD6E4A3D267" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_9CEB67838712D0ECD023BCD6E4A27502" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_86C7F2697D5B13BA73BCBCD6E4A3D267" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AntidilutiveSecuritiesNameDomain" xlink:label="loc_us-gaap_AntidilutiveSecuritiesNameDomain_6EA38240FE9CC617E1B1BCD6E4A355C5_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_86C7F2697D5B13BA73BCBCD6E4A3D267" xlink:to="loc_us-gaap_AntidilutiveSecuritiesNameDomain_6EA38240FE9CC617E1B1BCD6E4A355C5_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AntidilutiveSecuritiesNameDomain" xlink:label="loc_us-gaap_AntidilutiveSecuritiesNameDomain_6EA38240FE9CC617E1B1BCD6E4A355C5" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_86C7F2697D5B13BA73BCBCD6E4A3D267" xlink:to="loc_us-gaap_AntidilutiveSecuritiesNameDomain_6EA38240FE9CC617E1B1BCD6E4A355C5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockCompensationPlanMember" xlink:label="loc_us-gaap_StockCompensationPlanMember_29D65CD7D67D741100B8BCD6E4A369BA" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_6EA38240FE9CC617E1B1BCD6E4A355C5" xlink:to="loc_us-gaap_StockCompensationPlanMember_29D65CD7D67D741100B8BCD6E4A369BA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_65F6207DA1A6B802F9F8BCD6E4A32F2D" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_53E8E33EFF29BFD9CA36BCD6E4A32E45" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_65F6207DA1A6B802F9F8BCD6E4A32F2D" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/EarningsPerShareScheduleOfEarningsPerShareBasicAndDilutedDetails" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/EarningsPerShareTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/FairValueMeasurements" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/FairValueMeasurementsAssetsAndLiabilitiesMeasuredAtFairValueOnRecurringBasisDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_5D968F7998EC3603E5CFBEBC4607D93A" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_DC19A68A424340C2F65EBEBC46032BAE" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_5D968F7998EC3603E5CFBEBC4607D93A" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_DC19A68A424340C2F65EBEBC46032BAE" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_7FD5A78D7D2938A4607EBEBC46039552" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_DC19A68A424340C2F65EBEBC46032BAE" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_7FD5A78D7D2938A4607EBEBC46039552" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_43CE1131C75588A8F34ABEBC46032C6C_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_7FD5A78D7D2938A4607EBEBC46039552" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_43CE1131C75588A8F34ABEBC46032C6C_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_43CE1131C75588A8F34ABEBC46032C6C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_7FD5A78D7D2938A4607EBEBC46039552" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_43CE1131C75588A8F34ABEBC46032C6C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementsRecurringMember" xlink:label="loc_us-gaap_FairValueMeasurementsRecurringMember_28649B8D11CAA01A7491BEBC4604DAF7" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_43CE1131C75588A8F34ABEBC46032C6C" xlink:to="loc_us-gaap_FairValueMeasurementsRecurringMember_28649B8D11CAA01A7491BEBC4604DAF7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_46ED260F6F529F44FF60BEBC4604ACF0" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_DC19A68A424340C2F65EBEBC46032BAE" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_46ED260F6F529F44FF60BEBC4604ACF0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_BECBEEE0AD94E9A3B291BEBC460428B7_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_46ED260F6F529F44FF60BEBC4604ACF0" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_BECBEEE0AD94E9A3B291BEBC460428B7_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_BECBEEE0AD94E9A3B291BEBC460428B7" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_46ED260F6F529F44FF60BEBC4604ACF0" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_BECBEEE0AD94E9A3B291BEBC460428B7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueInputsLevel1Member" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_A9C37233B57DC9BB64F2BEBC46046284" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_BECBEEE0AD94E9A3B291BEBC460428B7" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_A9C37233B57DC9BB64F2BEBC46046284" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueInputsLevel2Member" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_F9E814486873EBC3FA8BBEBC4605DA3F" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_BECBEEE0AD94E9A3B291BEBC460428B7" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_F9E814486873EBC3FA8BBEBC4605DA3F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueInputsLevel3Member" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_EB5313E060B43AFA1F22BEBC46059F48" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_BECBEEE0AD94E9A3B291BEBC460428B7" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_EB5313E060B43AFA1F22BEBC46059F48" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_HedgingDesignationAxis" xlink:label="loc_us-gaap_HedgingDesignationAxis_B4961E5C5BCAA8DFE1C7BEBC46051651" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_DC19A68A424340C2F65EBEBC46032BAE" xlink:to="loc_us-gaap_HedgingDesignationAxis_B4961E5C5BCAA8DFE1C7BEBC46051651" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="loc_us-gaap_HedgingDesignationDomain_C5206DCFA8F48AB7AE7BBEBC4605629A_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_HedgingDesignationAxis_B4961E5C5BCAA8DFE1C7BEBC46051651" xlink:to="loc_us-gaap_HedgingDesignationDomain_C5206DCFA8F48AB7AE7BBEBC4605629A_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_HedgingDesignationDomain" xlink:label="loc_us-gaap_HedgingDesignationDomain_C5206DCFA8F48AB7AE7BBEBC4605629A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_HedgingDesignationAxis_B4961E5C5BCAA8DFE1C7BEBC46051651" xlink:to="loc_us-gaap_HedgingDesignationDomain_C5206DCFA8F48AB7AE7BBEBC4605629A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DesignatedAsHedgingInstrumentMember" xlink:label="loc_us-gaap_DesignatedAsHedgingInstrumentMember_B879E1A6A6C744E0133DBEBC4605FF23" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_C5206DCFA8F48AB7AE7BBEBC4605629A" xlink:to="loc_us-gaap_DesignatedAsHedgingInstrumentMember_B879E1A6A6C744E0133DBEBC4605FF23" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NondesignatedMember" xlink:label="loc_us-gaap_NondesignatedMember_E3D68280CEE5CF93FBC6BEBC4606554B" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_HedgingDesignationDomain_C5206DCFA8F48AB7AE7BBEBC4605629A" xlink:to="loc_us-gaap_NondesignatedMember_E3D68280CEE5CF93FBC6BEBC4606554B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeInstrumentRiskAxis" xlink:label="loc_us-gaap_DerivativeInstrumentRiskAxis_4480C39D9888DD3802AEBEBC4606DA46" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable_DC19A68A424340C2F65EBEBC46032BAE" xlink:to="loc_us-gaap_DerivativeInstrumentRiskAxis_4480C39D9888DD3802AEBEBC4606DA46" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_223A28212FF95AED53DBBEBC46063A3A_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_4480C39D9888DD3802AEBEBC4606DA46" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_223A28212FF95AED53DBBEBC46063A3A_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeContractTypeDomain" xlink:label="loc_us-gaap_DerivativeContractTypeDomain_223A28212FF95AED53DBBEBC46063A3A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DerivativeInstrumentRiskAxis_4480C39D9888DD3802AEBEBC4606DA46" xlink:to="loc_us-gaap_DerivativeContractTypeDomain_223A28212FF95AED53DBBEBC46063A3A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ForeignExchangeContractMember" xlink:label="loc_us-gaap_ForeignExchangeContractMember_D6BE97407EE50C17BFD5BEBC4606B9F5" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_223A28212FF95AED53DBBEBC46063A3A" xlink:to="loc_us-gaap_ForeignExchangeContractMember_D6BE97407EE50C17BFD5BEBC4606B9F5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InterestRateContractMember" xlink:label="loc_us-gaap_InterestRateContractMember_93A36BBC047E8CD27992BEBC4606090C" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DerivativeContractTypeDomain_223A28212FF95AED53DBBEBC46063A3A" xlink:to="loc_us-gaap_InterestRateContractMember_93A36BBC047E8CD27992BEBC4606090C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AssetsFairValueDisclosureAbstract" xlink:label="loc_us-gaap_AssetsFairValueDisclosureAbstract_C4AF5236F4792F072099BEBC4607991A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_5D968F7998EC3603E5CFBEBC4607D93A" xlink:to="loc_us-gaap_AssetsFairValueDisclosureAbstract_C4AF5236F4792F072099BEBC4607991A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeAssets" xlink:label="loc_us-gaap_DerivativeAssets_7380C6BB803AFA17DED9BEBC4607A040" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_C4AF5236F4792F072099BEBC4607991A" xlink:to="loc_us-gaap_DerivativeAssets_7380C6BB803AFA17DED9BEBC4607A040" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AssetsFairValueDisclosure" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_AF1226B1B232456703F4BEBC46079C72" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AssetsFairValueDisclosureAbstract_C4AF5236F4792F072099BEBC4607991A" xlink:to="loc_us-gaap_AssetsFairValueDisclosure_AF1226B1B232456703F4BEBC46079C72" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract" xlink:label="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_00FCFBAD0952F13700C5BEBC46084805" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems_5D968F7998EC3603E5CFBEBC4607D93A" xlink:to="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_00FCFBAD0952F13700C5BEBC46084805" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DerivativeLiabilities" xlink:label="loc_us-gaap_DerivativeLiabilities_1E3401061C5C93F17207BEBC46082590" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_00FCFBAD0952F13700C5BEBC46084805" xlink:to="loc_us-gaap_DerivativeLiabilities_1E3401061C5C93F17207BEBC46082590" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_296C913F7CCF9D42D904BEBC46086964" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_00FCFBAD0952F13700C5BEBC46084805" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_296C913F7CCF9D42D904BEBC46086964" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosure" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosure_580C31AF7025197ED21CBEBC460803C5" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FinancialLiabilitiesFairValueDisclosureAbstract_00FCFBAD0952F13700C5BEBC46084805" xlink:to="loc_us-gaap_LiabilitiesFairValueDisclosure_580C31AF7025197ED21CBEBC460803C5" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/FairValueMeasurementsContingentConsiderationReconciliationDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionLineItems" xlink:label="loc_us-gaap_BusinessAcquisitionLineItems_D46FF12F9D03E00DF9D5BCD6E52C6E4F" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_F77052896D3ACCD3CD3DBCD6E529AD39" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_D46FF12F9D03E00DF9D5BCD6E52C6E4F" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_F77052896D3ACCD3CD3DBCD6E529AD39" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_7041925217E77DC073DABCD6E52A5E33" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_F77052896D3ACCD3CD3DBCD6E529AD39" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_7041925217E77DC073DABCD6E52A5E33" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_29A6B2DF9E2DF715AADFBCD6E52A8339_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_7041925217E77DC073DABCD6E52A5E33" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_29A6B2DF9E2DF715AADFBCD6E52A8339_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_29A6B2DF9E2DF715AADFBCD6E52A8339" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_7041925217E77DC073DABCD6E52A5E33" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_29A6B2DF9E2DF715AADFBCD6E52A8339" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementsRecurringMember" xlink:label="loc_us-gaap_FairValueMeasurementsRecurringMember_576AD201B39733A2E158BCD6E52A736B" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_29A6B2DF9E2DF715AADFBCD6E52A8339" xlink:to="loc_us-gaap_FairValueMeasurementsRecurringMember_576AD201B39733A2E158BCD6E52A736B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_1F48D798C0E017D93CA3BCD6E52AA5AF" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_F77052896D3ACCD3CD3DBCD6E529AD39" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_1F48D798C0E017D93CA3BCD6E52AA5AF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_BE8C5E21F90542C08B79BCD6E52A0BB9_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_1F48D798C0E017D93CA3BCD6E52AA5AF" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_BE8C5E21F90542C08B79BCD6E52A0BB9_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_BE8C5E21F90542C08B79BCD6E52A0BB9" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_1F48D798C0E017D93CA3BCD6E52AA5AF" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_BE8C5E21F90542C08B79BCD6E52A0BB9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueInputsLevel3Member" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_C8DAC1EF3CE8EE6BDE85BCD6E52BD143" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_BE8C5E21F90542C08B79BCD6E52A0BB9" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_C8DAC1EF3CE8EE6BDE85BCD6E52BD143" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementLocationAxis" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_8651CACD1191EFA19166BCD6E52BDB76" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionTable_F77052896D3ACCD3CD3DBCD6E529AD39" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_8651CACD1191EFA19166BCD6E52BDB76" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_FBE1EF4C1DB096CDDC23BCD6E52B3FD9_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_8651CACD1191EFA19166BCD6E52BDB76" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_FBE1EF4C1DB096CDDC23BCD6E52B3FD9_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeStatementLocationDomain" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_FBE1EF4C1DB096CDDC23BCD6E52B3FD9" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_8651CACD1191EFA19166BCD6E52BDB76" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_FBE1EF4C1DB096CDDC23BCD6E52B3FD9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CostOfSalesMember" xlink:label="loc_us-gaap_CostOfSalesMember_BAE90DC5775C29B1B6F7BCD6E52B83F2" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_FBE1EF4C1DB096CDDC23BCD6E52B3FD9" xlink:to="loc_us-gaap_CostOfSalesMember_BAE90DC5775C29B1B6F7BCD6E52B83F2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseMember" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember_CA01044875AE56A82ECEBCD6E52C8AC5" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_FBE1EF4C1DB096CDDC23BCD6E52B3FD9" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseMember_CA01044875AE56A82ECEBCD6E52C8AC5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_54333664DD5604D97AC0BCD6E52C49AB" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_D46FF12F9D03E00DF9D5BCD6E52C6E4F" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_54333664DD5604D97AC0BCD6E52C49AB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_CC0CAA7486BEC3607A30BCD6E52CA35F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_54333664DD5604D97AC0BCD6E52C49AB" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_CC0CAA7486BEC3607A30BCD6E52CA35F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements_9C547DFF607E983A798BBCD6E52D9D2B" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_54333664DD5604D97AC0BCD6E52C49AB" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements_9C547DFF607E983A798BBCD6E52D9D2B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings_B1A5DF287F57FE3A7260BCD6E52DFAEA" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_54333664DD5604D97AC0BCD6E52C49AB" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings_B1A5DF287F57FE3A7260BCD6E52DFAEA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInOtherComprehensiveIncome" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInOtherComprehensiveIncome_4E6EEACC32B4258DE85CBCD6E52D81A0" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_54333664DD5604D97AC0BCD6E52C49AB" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInOtherComprehensiveIncome_4E6EEACC32B4258DE85CBCD6E52D81A0" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_FairValueMeasurementwithUnobservableInputsReconciliationRecurringBasisCurrentLiabilityValue" xlink:label="loc_livn_FairValueMeasurementwithUnobservableInputsReconciliationRecurringBasisCurrentLiabilityValue_27AB6EE9405EDB9EB9F5BCD6E52D7802" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_54333664DD5604D97AC0BCD6E52C49AB" xlink:to="loc_livn_FairValueMeasurementwithUnobservableInputsReconciliationRecurringBasisCurrentLiabilityValue_27AB6EE9405EDB9EB9F5BCD6E52D7802" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_FairValueMeasurementwithUnobservableInputsReconciliationRecurringBasisNoncurrentLiabilityValue" xlink:label="loc_livn_FairValueMeasurementwithUnobservableInputsReconciliationRecurringBasisNoncurrentLiabilityValue_4CA6E5D0D4F343FE5B9BBCD6E52DFF81" xlink:type="locator" />
    <link:definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_54333664DD5604D97AC0BCD6E52C49AB" xlink:to="loc_livn_FairValueMeasurementwithUnobservableInputsReconciliationRecurringBasisNoncurrentLiabilityValue_4CA6E5D0D4F343FE5B9BBCD6E52DFF81" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PaymentForContingentConsiderationLiabilityInvestingActivities" xlink:label="loc_us-gaap_PaymentForContingentConsiderationLiabilityInvestingActivities_332AB0062A22DAE7E4CFBCD6E52D4E2D" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_D46FF12F9D03E00DF9D5BCD6E52C6E4F" xlink:to="loc_us-gaap_PaymentForContingentConsiderationLiabilityInvestingActivities_332AB0062A22DAE7E4CFBCD6E52D4E2D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_516139744D89E0B12968BCD6E52E8F2C" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionLineItems_D46FF12F9D03E00DF9D5BCD6E52C6E4F" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1_516139744D89E0B12968BCD6E52E8F2C" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/FairValueMeasurementsFairValueOfContingentConsiderationByAcquisitionDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionContingentConsiderationLineItems" xlink:label="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_BD126291791568BD0623BCD6E524A891" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable" xlink:label="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_CB5E218E89A1FFC767EDBCD6E5210F42" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_BD126291791568BD0623BCD6E524A891" xlink:to="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_CB5E218E89A1FFC767EDBCD6E5210F42" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_CD89E170B7C97EEA33B1BCD6E521B7B2" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_CB5E218E89A1FFC767EDBCD6E5210F42" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_CD89E170B7C97EEA33B1BCD6E521B7B2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_C78FB64EEEB9D1C492BBBCD6E521196E_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_CD89E170B7C97EEA33B1BCD6E521B7B2" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_C78FB64EEEB9D1C492BBBCD6E521196E_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_C78FB64EEEB9D1C492BBBCD6E521196E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_CD89E170B7C97EEA33B1BCD6E521B7B2" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_C78FB64EEEB9D1C492BBBCD6E521196E" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_ImTheraMedicalInc.Member" xlink:label="loc_livn_ImTheraMedicalInc.Member_E154697AC0C6C58924B7BCD6E522FC67" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_C78FB64EEEB9D1C492BBBCD6E521196E" xlink:to="loc_livn_ImTheraMedicalInc.Member_E154697AC0C6C58924B7BCD6E522FC67" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_TandemLifeMember" xlink:label="loc_livn_TandemLifeMember_E772ABB4A8B34870E797BCD6E522C94E" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_C78FB64EEEB9D1C492BBBCD6E521196E" xlink:to="loc_livn_TandemLifeMember_E772ABB4A8B34870E797BCD6E522C94E" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_MiamiInstrumentsLLCMember" xlink:label="loc_livn_MiamiInstrumentsLLCMember_ABCD15C269497FA329C1BCD6E522007A" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_C78FB64EEEB9D1C492BBBCD6E521196E" xlink:to="loc_livn_MiamiInstrumentsLLCMember_ABCD15C269497FA329C1BCD6E522007A" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_DrilltexMember" xlink:label="loc_livn_DrilltexMember_A7A7BFA67FA79287D214BCD6E52281B6" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_C78FB64EEEB9D1C492BBBCD6E521196E" xlink:to="loc_livn_DrilltexMember_A7A7BFA67FA79287D214BCD6E52281B6" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_OtherMember" xlink:label="loc_livn_OtherMember_7D19FA4B593D3C59416FBCD6E522010F" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_C78FB64EEEB9D1C492BBBCD6E521196E" xlink:to="loc_livn_OtherMember_7D19FA4B593D3C59416FBCD6E522010F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_A5B4CDC12C14226C762CBCD6E523194C" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_CB5E218E89A1FFC767EDBCD6E5210F42" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_A5B4CDC12C14226C762CBCD6E523194C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_4449DCEE0D2264D35479BCD6E5233E6E_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_A5B4CDC12C14226C762CBCD6E523194C" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_4449DCEE0D2264D35479BCD6E5233E6E_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_4449DCEE0D2264D35479BCD6E5233E6E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_A5B4CDC12C14226C762CBCD6E523194C" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_4449DCEE0D2264D35479BCD6E5233E6E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementsRecurringMember" xlink:label="loc_us-gaap_FairValueMeasurementsRecurringMember_8BB40DE8601ACF2D8E67BCD6E5236464" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_4449DCEE0D2264D35479BCD6E5233E6E" xlink:to="loc_us-gaap_FairValueMeasurementsRecurringMember_8BB40DE8601ACF2D8E67BCD6E5236464" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_7209228494226D210B88BCD6E523BDE3" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfBusinessAcquisitionsByAcquisitionContingentConsiderationTable_CB5E218E89A1FFC767EDBCD6E5210F42" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_7209228494226D210B88BCD6E523BDE3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_4CC347A421940848FB7FBCD6E523CE10_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_7209228494226D210B88BCD6E523BDE3" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_4CC347A421940848FB7FBCD6E523CE10_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_4CC347A421940848FB7FBCD6E523CE10" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_7209228494226D210B88BCD6E523BDE3" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_4CC347A421940848FB7FBCD6E523CE10" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueInputsLevel3Member" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_6BCC7F4AA2C3953B87BEBCD6E524701B" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_4CC347A421940848FB7FBCD6E523CE10" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_6BCC7F4AA2C3953B87BEBCD6E524701B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationContingentConsiderationLiability" xlink:label="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_BD2685D97B72D2A4AA30BCD6E5243F75" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_BD126291791568BD0623BCD6E524A891" xlink:to="loc_us-gaap_BusinessCombinationContingentConsiderationLiability_BD2685D97B72D2A4AA30BCD6E5243F75" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_B42FB5F2FF61F7107F65BCD6E5242DB8" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionContingentConsiderationLineItems_BD126291791568BD0623BCD6E524A891" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_B42FB5F2FF61F7107F65BCD6E5242DB8" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/FairValueMeasurementsLevel3ValuationsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesLineItems" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesLineItems_B184681D565E1E215ADBBCD6E51C0053" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTable" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTable_69F3751CEAF91C1999A1BCD6E51634A0" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesLineItems_B184681D565E1E215ADBBCD6E51C0053" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTable_69F3751CEAF91C1999A1BCD6E51634A0" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAxis" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_3A9191A60009B917061EBCD6E516A9E6" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTable_69F3751CEAF91C1999A1BCD6E51634A0" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_3A9191A60009B917061EBCD6E516A9E6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_EE92BA1C069355867F4CBCD6E517D7D6_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_3A9191A60009B917061EBCD6E516A9E6" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_EE92BA1C069355867F4CBCD6E517D7D6_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionAcquireeDomain" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_EE92BA1C069355867F4CBCD6E517D7D6" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_3A9191A60009B917061EBCD6E516A9E6" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_EE92BA1C069355867F4CBCD6E517D7D6" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_ImTheraMedicalInc.Member" xlink:label="loc_livn_ImTheraMedicalInc.Member_91CE5456F033E0A59E28BCD6E5172927" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_EE92BA1C069355867F4CBCD6E517D7D6" xlink:to="loc_livn_ImTheraMedicalInc.Member_91CE5456F033E0A59E28BCD6E5172927" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_TandemLifeMember" xlink:label="loc_livn_TandemLifeMember_5BB1E8DC74B8FA836BF0BCD6E5173E28" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_EE92BA1C069355867F4CBCD6E517D7D6" xlink:to="loc_livn_TandemLifeMember_5BB1E8DC74B8FA836BF0BCD6E5173E28" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_MiamiInstrumentsLLCMember" xlink:label="loc_livn_MiamiInstrumentsLLCMember_558AA18467BB3D2FB6E4BCD6E518ADCC" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_EE92BA1C069355867F4CBCD6E517D7D6" xlink:to="loc_livn_MiamiInstrumentsLLCMember_558AA18467BB3D2FB6E4BCD6E518ADCC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeAxis" xlink:label="loc_srt_RangeAxis_5C0970309973B02B702DBCD6E518794C" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTable_69F3751CEAF91C1999A1BCD6E51634A0" xlink:to="loc_srt_RangeAxis_5C0970309973B02B702DBCD6E518794C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeMember" xlink:label="loc_srt_RangeMember_B8BA32F81167F8DA4855BCD6E518C120_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_5C0970309973B02B702DBCD6E518794C" xlink:to="loc_srt_RangeMember_B8BA32F81167F8DA4855BCD6E518C120_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeMember" xlink:label="loc_srt_RangeMember_B8BA32F81167F8DA4855BCD6E518C120" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_5C0970309973B02B702DBCD6E518794C" xlink:to="loc_srt_RangeMember_B8BA32F81167F8DA4855BCD6E518C120" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MinimumMember" xlink:label="loc_srt_MinimumMember_B6722E4BE9CCB3826154BCD6E518C536" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_B8BA32F81167F8DA4855BCD6E518C120" xlink:to="loc_srt_MinimumMember_B6722E4BE9CCB3826154BCD6E518C536" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MaximumMember" xlink:label="loc_srt_MaximumMember_EB189D3241FABD7F4EBABCD6E5180589" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_B8BA32F81167F8DA4855BCD6E518C120" xlink:to="loc_srt_MaximumMember_EB189D3241FABD7F4EBABCD6E5180589" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ValuationTechniqueAxis" xlink:label="loc_us-gaap_ValuationTechniqueAxis_F50253F44426FA0AAFF0BCD6E5194643" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTable_69F3751CEAF91C1999A1BCD6E51634A0" xlink:to="loc_us-gaap_ValuationTechniqueAxis_F50253F44426FA0AAFF0BCD6E5194643" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ValuationTechniqueDomain" xlink:label="loc_us-gaap_ValuationTechniqueDomain_C7FEDE578DF5FAB22327BCD6E5195C67_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ValuationTechniqueAxis_F50253F44426FA0AAFF0BCD6E5194643" xlink:to="loc_us-gaap_ValuationTechniqueDomain_C7FEDE578DF5FAB22327BCD6E5195C67_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ValuationTechniqueDomain" xlink:label="loc_us-gaap_ValuationTechniqueDomain_C7FEDE578DF5FAB22327BCD6E5195C67" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ValuationTechniqueAxis_F50253F44426FA0AAFF0BCD6E5194643" xlink:to="loc_us-gaap_ValuationTechniqueDomain_C7FEDE578DF5FAB22327BCD6E5195C67" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ValuationTechniqueDiscountedCashFlowMember" xlink:label="loc_us-gaap_ValuationTechniqueDiscountedCashFlowMember_43E789161A1123BFACCABCD6E519EBED" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ValuationTechniqueDomain_C7FEDE578DF5FAB22327BCD6E5195C67" xlink:to="loc_us-gaap_ValuationTechniqueDiscountedCashFlowMember_43E789161A1123BFACCABCD6E519EBED" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_ValuationTechniqueMonteCarloSimulationMember" xlink:label="loc_livn_ValuationTechniqueMonteCarloSimulationMember_7656AFA45770A80E4ED3BCD6E519F733" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ValuationTechniqueDomain_C7FEDE578DF5FAB22327BCD6E5195C67" xlink:to="loc_livn_ValuationTechniqueMonteCarloSimulationMember_7656AFA45770A80E4ED3BCD6E519F733" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_95DC5CA11EF4541F7C7DBCD6E5198A58" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTable_69F3751CEAF91C1999A1BCD6E51634A0" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_95DC5CA11EF4541F7C7DBCD6E5198A58" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_5DA7C206508E891FA3B2BCD6E51AB647_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_95DC5CA11EF4541F7C7DBCD6E5198A58" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_5DA7C206508E891FA3B2BCD6E51AB647_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_5DA7C206508E891FA3B2BCD6E51AB647" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_95DC5CA11EF4541F7C7DBCD6E5198A58" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_5DA7C206508E891FA3B2BCD6E51AB647" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FairValueInputsLevel3Member" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_96C32C02E5596844CABBBCD6E51A403E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_5DA7C206508E891FA3B2BCD6E51AB647" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_96C32C02E5596844CABBBCD6E51A403E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_MeasurementInputTypeAxis" xlink:label="loc_us-gaap_MeasurementInputTypeAxis_AF7C7C6C0C0AFF9219F6BCD6E51A8C72" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTable_69F3751CEAF91C1999A1BCD6E51634A0" xlink:to="loc_us-gaap_MeasurementInputTypeAxis_AF7C7C6C0C0AFF9219F6BCD6E51A8C72" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_MeasurementInputTypeDomain" xlink:label="loc_us-gaap_MeasurementInputTypeDomain_E5848BFD02D38CC35F1BBCD6E51A7012_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_MeasurementInputTypeAxis_AF7C7C6C0C0AFF9219F6BCD6E51A8C72" xlink:to="loc_us-gaap_MeasurementInputTypeDomain_E5848BFD02D38CC35F1BBCD6E51A7012_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_MeasurementInputTypeDomain" xlink:label="loc_us-gaap_MeasurementInputTypeDomain_E5848BFD02D38CC35F1BBCD6E51A7012" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_MeasurementInputTypeAxis_AF7C7C6C0C0AFF9219F6BCD6E51A8C72" xlink:to="loc_us-gaap_MeasurementInputTypeDomain_E5848BFD02D38CC35F1BBCD6E51A7012" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_MeasurementInputDiscountRateMember" xlink:label="loc_us-gaap_MeasurementInputDiscountRateMember_5DAD3F6A89636CAA4EBEBCD6E51BEB6E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_E5848BFD02D38CC35F1BBCD6E51A7012" xlink:to="loc_us-gaap_MeasurementInputDiscountRateMember_5DAD3F6A89636CAA4EBEBCD6E51BEB6E" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_MeasurementInputProbabilityofPaymentMember" xlink:label="loc_livn_MeasurementInputProbabilityofPaymentMember_DDE7F149207475205BC6BCD6E51BF339" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_E5848BFD02D38CC35F1BBCD6E51A7012" xlink:to="loc_livn_MeasurementInputProbabilityofPaymentMember_DDE7F149207475205BC6BCD6E51BF339" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_MeasurementInputRiskadjustedDiscountRateMember" xlink:label="loc_livn_MeasurementInputRiskadjustedDiscountRateMember_EA8870ED0D73532F69F0BCD6E51BEF6A" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_E5848BFD02D38CC35F1BBCD6E51A7012" xlink:to="loc_livn_MeasurementInputRiskadjustedDiscountRateMember_EA8870ED0D73532F69F0BCD6E51BEF6A" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_MeasurementInputCreditRiskDiscountRateMember" xlink:label="loc_livn_MeasurementInputCreditRiskDiscountRateMember_F19CEE88C08ADEE9C8EEBCD6E51B96DE" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_E5848BFD02D38CC35F1BBCD6E51A7012" xlink:to="loc_livn_MeasurementInputCreditRiskDiscountRateMember_F19CEE88C08ADEE9C8EEBCD6E51B96DE" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_MeasurementInputRevenueVolatilityMember" xlink:label="loc_livn_MeasurementInputRevenueVolatilityMember_D5503F47DCAB272E1247BCD6E51B8736" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_E5848BFD02D38CC35F1BBCD6E51A7012" xlink:to="loc_livn_MeasurementInputRevenueVolatilityMember_D5503F47DCAB272E1247BCD6E51B8736" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_BusinessCombinationContingentConsiderationMeasurementInput" xlink:label="loc_livn_BusinessCombinationContingentConsiderationMeasurementInput_3EAE3615531DAD6FE00EBCD6E51C1165" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesLineItems_B184681D565E1E215ADBBCD6E51C0053" xlink:to="loc_livn_BusinessCombinationContingentConsiderationMeasurementInput_3EAE3615531DAD6FE00EBCD6E51C1165" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/FairValueMeasurementsTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/FinancingArrangements" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/FinancingArrangementsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="loc_us-gaap_DebtInstrumentLineItems_BAD3B63FBE55A9A1FF97BCD6E5015042" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="loc_us-gaap_DebtInstrumentTable_BD6CC847259DAE3A098CBCD6E4FF445B" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DebtInstrumentLineItems_BAD3B63FBE55A9A1FF97BCD6E5015042" xlink:to="loc_us-gaap_DebtInstrumentTable_BD6CC847259DAE3A098CBCD6E4FF445B" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeAxis" xlink:label="loc_srt_RangeAxis_7868245BA5E50F3BDE57BCD6E500B1A9" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_BD6CC847259DAE3A098CBCD6E4FF445B" xlink:to="loc_srt_RangeAxis_7868245BA5E50F3BDE57BCD6E500B1A9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeMember" xlink:label="loc_srt_RangeMember_9A843896A35C38422973BCD6E500CE33_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_7868245BA5E50F3BDE57BCD6E500B1A9" xlink:to="loc_srt_RangeMember_9A843896A35C38422973BCD6E500CE33_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeMember" xlink:label="loc_srt_RangeMember_9A843896A35C38422973BCD6E500CE33" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_7868245BA5E50F3BDE57BCD6E500B1A9" xlink:to="loc_srt_RangeMember_9A843896A35C38422973BCD6E500CE33" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MinimumMember" xlink:label="loc_srt_MinimumMember_B1A2C67C05E0B2A64BFCBCD6E500C3B3" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_9A843896A35C38422973BCD6E500CE33" xlink:to="loc_srt_MinimumMember_B1A2C67C05E0B2A64BFCBCD6E500C3B3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MaximumMember" xlink:label="loc_srt_MaximumMember_21C42758077729FBE721BCD6E500BB71" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_9A843896A35C38422973BCD6E500CE33" xlink:to="loc_srt_MaximumMember_21C42758077729FBE721BCD6E500BB71" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CreditFacilityAxis" xlink:label="loc_us-gaap_CreditFacilityAxis_1AC3C0AB15107DA5522DBCD6E5000B76" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_BD6CC847259DAE3A098CBCD6E4FF445B" xlink:to="loc_us-gaap_CreditFacilityAxis_1AC3C0AB15107DA5522DBCD6E5000B76" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="loc_us-gaap_CreditFacilityDomain_9F64481365728A49E43DBCD6E501B674_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_CreditFacilityAxis_1AC3C0AB15107DA5522DBCD6E5000B76" xlink:to="loc_us-gaap_CreditFacilityDomain_9F64481365728A49E43DBCD6E501B674_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CreditFacilityDomain" xlink:label="loc_us-gaap_CreditFacilityDomain_9F64481365728A49E43DBCD6E501B674" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_CreditFacilityAxis_1AC3C0AB15107DA5522DBCD6E5000B76" xlink:to="loc_us-gaap_CreditFacilityDomain_9F64481365728A49E43DBCD6E501B674" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RevolvingCreditFacilityMember" xlink:label="loc_us-gaap_RevolvingCreditFacilityMember_E4D127646691F88B3E40BCD6E5016D4F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CreditFacilityDomain_9F64481365728A49E43DBCD6E501B674" xlink:to="loc_us-gaap_RevolvingCreditFacilityMember_E4D127646691F88B3E40BCD6E5016D4F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShortTermBorrowings" xlink:label="loc_us-gaap_ShortTermBorrowings_7F3176982862FDF627E3BCD6E501D368" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_BAD3B63FBE55A9A1FF97BCD6E5015042" xlink:to="loc_us-gaap_ShortTermBorrowings_7F3176982862FDF627E3BCD6E501D368" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage" xlink:label="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_0210986A52C2A98E795EBCD6E502B9F1" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_BAD3B63FBE55A9A1FF97BCD6E5015042" xlink:to="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_0210986A52C2A98E795EBCD6E502B9F1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentTerm" xlink:label="loc_us-gaap_DebtInstrumentTerm_8579E53D717D5354BF90BCD6E502C41A" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_BAD3B63FBE55A9A1FF97BCD6E5015042" xlink:to="loc_us-gaap_DebtInstrumentTerm_8579E53D717D5354BF90BCD6E502C41A" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/FinancingArrangementsScheduleOfDebtDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentLineItems" xlink:label="loc_us-gaap_DebtInstrumentLineItems_14E34A21366002C95D69BCD6E50B78BE" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentTable" xlink:label="loc_us-gaap_DebtInstrumentTable_261CEDF2A3527A6E5666BCD6E507F549" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DebtInstrumentLineItems_14E34A21366002C95D69BCD6E50B78BE" xlink:to="loc_us-gaap_DebtInstrumentTable_261CEDF2A3527A6E5666BCD6E507F549" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_A33BF1AC067834214D51BCD6E5072676" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_261CEDF2A3527A6E5666BCD6E507F549" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_A33BF1AC067834214D51BCD6E5072676" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_7820C980A088B2DA0966BCD6E507FCE8_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_A33BF1AC067834214D51BCD6E5072676" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_7820C980A088B2DA0966BCD6E507FCE8_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongtermDebtTypeDomain" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_7820C980A088B2DA0966BCD6E507FCE8" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_A33BF1AC067834214D51BCD6E5072676" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_7820C980A088B2DA0966BCD6E507FCE8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LoansPayableMember" xlink:label="loc_us-gaap_LoansPayableMember_D58FEE951C5CC3E9A6F7BCD6E508EEA1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_7820C980A088B2DA0966BCD6E507FCE8" xlink:to="loc_us-gaap_LoansPayableMember_D58FEE951C5CC3E9A6F7BCD6E508EEA1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherDebtSecuritiesMember" xlink:label="loc_us-gaap_OtherDebtSecuritiesMember_CF8466CC9971A89011FBBCD6E508CD7C" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_7820C980A088B2DA0966BCD6E507FCE8" xlink:to="loc_us-gaap_OtherDebtSecuritiesMember_CF8466CC9971A89011FBBCD6E508CD7C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LetterOfCreditMember" xlink:label="loc_us-gaap_LetterOfCreditMember_03422C6AF28D02EE6AC3BCD6E5088C88" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_7820C980A088B2DA0966BCD6E507FCE8" xlink:to="loc_us-gaap_LetterOfCreditMember_03422C6AF28D02EE6AC3BCD6E5088C88" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditFacilityAxis" xlink:label="loc_us-gaap_LineOfCreditFacilityAxis_B6CE28BD866161DB3CA9BCD6E508877A" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_261CEDF2A3527A6E5666BCD6E507F549" xlink:to="loc_us-gaap_LineOfCreditFacilityAxis_B6CE28BD866161DB3CA9BCD6E508877A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditFacilityLenderDomain" xlink:label="loc_us-gaap_LineOfCreditFacilityLenderDomain_CABD2EA5625C619B68FDBCD6E508ECC4_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LineOfCreditFacilityAxis_B6CE28BD866161DB3CA9BCD6E508877A" xlink:to="loc_us-gaap_LineOfCreditFacilityLenderDomain_CABD2EA5625C619B68FDBCD6E508ECC4_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditFacilityLenderDomain" xlink:label="loc_us-gaap_LineOfCreditFacilityLenderDomain_CABD2EA5625C619B68FDBCD6E508ECC4" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LineOfCreditFacilityAxis_B6CE28BD866161DB3CA9BCD6E508877A" xlink:to="loc_us-gaap_LineOfCreditFacilityLenderDomain_CABD2EA5625C619B68FDBCD6E508ECC4" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_DebtFacility2019Member" xlink:label="loc_livn_DebtFacility2019Member_CF66D2CEC35996BE5F85BCD6E509CFB3" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_CABD2EA5625C619B68FDBCD6E508ECC4" xlink:to="loc_livn_DebtFacility2019Member_CF66D2CEC35996BE5F85BCD6E509CFB3" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_EuropeanInvestmentBank2017Member" xlink:label="loc_livn_EuropeanInvestmentBank2017Member_8F3C408D859B30346FFDBCD6E509DB3F" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_CABD2EA5625C619B68FDBCD6E508ECC4" xlink:to="loc_livn_EuropeanInvestmentBank2017Member_8F3C408D859B30346FFDBCD6E509DB3F" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_EuropeanInvestmentBank2014Member" xlink:label="loc_livn_EuropeanInvestmentBank2014Member_15C10CAE4D4D3274029BBCD6E509C219" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_CABD2EA5625C619B68FDBCD6E508ECC4" xlink:to="loc_livn_EuropeanInvestmentBank2014Member_15C10CAE4D4D3274029BBCD6E509C219" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_MediocreditoItalianoMember" xlink:label="loc_livn_MediocreditoItalianoMember_55273361F3EA7868ACE7BCD6E5099CAD" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_CABD2EA5625C619B68FDBCD6E508ECC4" xlink:to="loc_livn_MediocreditoItalianoMember_55273361F3EA7868ACE7BCD6E5099CAD" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_BankofAmericaMerrillLynchBancoMultiploS.A.Member" xlink:label="loc_livn_BankofAmericaMerrillLynchBancoMultiploS.A.Member_B72DEB3CDE572C83E730BCD6E50A8B95" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_CABD2EA5625C619B68FDBCD6E508ECC4" xlink:to="loc_livn_BankofAmericaMerrillLynchBancoMultiploS.A.Member_B72DEB3CDE572C83E730BCD6E50A8B95" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_BankofAmericaU.SMember" xlink:label="loc_livn_BankofAmericaU.SMember_373A5D71F1EE2D26F904BCD6E50A6A5F" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_CABD2EA5625C619B68FDBCD6E508ECC4" xlink:to="loc_livn_BankofAmericaU.SMember_373A5D71F1EE2D26F904BCD6E50A6A5F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeAxis" xlink:label="loc_srt_RangeAxis_522564F51A5FE2693A80BCD6E50AE6CF" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_261CEDF2A3527A6E5666BCD6E507F549" xlink:to="loc_srt_RangeAxis_522564F51A5FE2693A80BCD6E50AE6CF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeMember" xlink:label="loc_srt_RangeMember_279C5277A6BCEBF56720BCD6E50A70A5_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_522564F51A5FE2693A80BCD6E50AE6CF" xlink:to="loc_srt_RangeMember_279C5277A6BCEBF56720BCD6E50A70A5_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RangeMember" xlink:label="loc_srt_RangeMember_279C5277A6BCEBF56720BCD6E50A70A5" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_522564F51A5FE2693A80BCD6E50AE6CF" xlink:to="loc_srt_RangeMember_279C5277A6BCEBF56720BCD6E50A70A5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MinimumMember" xlink:label="loc_srt_MinimumMember_944CAE106FF046E43C6EBCD6E50A99C8" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_279C5277A6BCEBF56720BCD6E50A70A5" xlink:to="loc_srt_MinimumMember_944CAE106FF046E43C6EBCD6E50A99C8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_MaximumMember" xlink:label="loc_srt_MaximumMember_14C3539356227E93794DBCD6E50B1154" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_279C5277A6BCEBF56720BCD6E50A70A5" xlink:to="loc_srt_MaximumMember_14C3539356227E93794DBCD6E50B1154" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentCarryingAmount" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_3A29B87260C39DBEBF0DBCD6E50B9480" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_14E34A21366002C95D69BCD6E50B78BE" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_3A29B87260C39DBEBF0DBCD6E50B9480" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermDebtCurrent" xlink:label="loc_us-gaap_LongTermDebtCurrent_71F0D53D2D0139690A91BCD6E50B77B1" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_14E34A21366002C95D69BCD6E50B78BE" xlink:to="loc_us-gaap_LongTermDebtCurrent_71F0D53D2D0139690A91BCD6E50B77B1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LongTermDebtNoncurrent" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_9A558FF32F0E9C5C2D96BCD6E50B9381" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_14E34A21366002C95D69BCD6E50B78BE" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_9A558FF32F0E9C5C2D96BCD6E50B9381" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage" xlink:label="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_EBA8799C6FC326A0C468BCD6E50BDBB8" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_14E34A21366002C95D69BCD6E50B78BE" xlink:to="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_EBA8799C6FC326A0C468BCD6E50BDBB8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity" xlink:label="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_EC49444B3791936B7446BCD6E50C04D4" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_14E34A21366002C95D69BCD6E50B78BE" xlink:to="loc_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity_EC49444B3791936B7446BCD6E50C04D4" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_DebtInstrumentSemiAnnualPeriodicPaymentPercentageOfPrincipal" xlink:label="loc_livn_DebtInstrumentSemiAnnualPeriodicPaymentPercentageOfPrincipal_28A43F203B2D19AC0C4CBCD6E50CBC70" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_14E34A21366002C95D69BCD6E50B78BE" xlink:to="loc_livn_DebtInstrumentSemiAnnualPeriodicPaymentPercentageOfPrincipal_28A43F203B2D19AC0C4CBCD6E50CBC70" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/FinancingArrangementsTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformation" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformationChangesInCarryingAmountOfGoodwillDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_F3820A4DD73C05C57145BCD6A5DADB41" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_6C8C8D8C19AD8F71C1CBBCD6A5D9D1D2" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_F3820A4DD73C05C57145BCD6A5DADB41" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_6C8C8D8C19AD8F71C1CBBCD6A5D9D1D2" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_84F18CFED08BEB4067E1BCD6A5D95232" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_6C8C8D8C19AD8F71C1CBBCD6A5D9D1D2" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_84F18CFED08BEB4067E1BCD6A5D95232" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_F382B7D35FB70397E9BABCD6A5D9D7F5_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_84F18CFED08BEB4067E1BCD6A5D95232" xlink:to="loc_us-gaap_SegmentDomain_F382B7D35FB70397E9BABCD6A5D9D7F5_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_F382B7D35FB70397E9BABCD6A5D9D7F5" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_84F18CFED08BEB4067E1BCD6A5D95232" xlink:to="loc_us-gaap_SegmentDomain_F382B7D35FB70397E9BABCD6A5D9D7F5" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_NeuromodulationSegmentMember" xlink:label="loc_livn_NeuromodulationSegmentMember_2E1B502FB3F06B4D2A25BCD6A5DABBDC" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_F382B7D35FB70397E9BABCD6A5D9D7F5" xlink:to="loc_livn_NeuromodulationSegmentMember_2E1B502FB3F06B4D2A25BCD6A5DABBDC" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_CardiovascularSegmentMember" xlink:label="loc_livn_CardiovascularSegmentMember_031DEDE76F9435D92628BCD6A5DA13FC" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_F382B7D35FB70397E9BABCD6A5D9D7F5" xlink:to="loc_livn_CardiovascularSegmentMember_031DEDE76F9435D92628BCD6A5DA13FC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillRollForward" xlink:label="loc_us-gaap_GoodwillRollForward_77D935917C8AE6918C63BCD6A5DBCD5F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_F3820A4DD73C05C57145BCD6A5DADB41" xlink:to="loc_us-gaap_GoodwillRollForward_77D935917C8AE6918C63BCD6A5DBCD5F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_DA6B4C76EFCD1F5F0626BCD6A5DBD98A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillRollForward_77D935917C8AE6918C63BCD6A5DBCD5F" xlink:to="loc_us-gaap_Goodwill_DA6B4C76EFCD1F5F0626BCD6A5DBD98A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_GoodwillTranslationAndPurchaseAccountingAdjustments" xlink:label="loc_us-gaap_GoodwillTranslationAndPurchaseAccountingAdjustments_EE4BBA9573CA34D9DB23BCD6A5DBF4EF" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillRollForward_77D935917C8AE6918C63BCD6A5DBCD5F" xlink:to="loc_us-gaap_GoodwillTranslationAndPurchaseAccountingAdjustments_EE4BBA9573CA34D9DB23BCD6A5DBF4EF" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformationGeographicAreasDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_3CAF89094F0D8CFEA520BCD6B5655D63" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_734650CF5A8F05054343BCD6B563462E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_3CAF89094F0D8CFEA520BCD6B5655D63" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_734650CF5A8F05054343BCD6B563462E" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_StatementGeographicalAxis" xlink:label="loc_srt_StatementGeographicalAxis_6123C8F93720A0738849BCD6B5641FBD" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_734650CF5A8F05054343BCD6B563462E" xlink:to="loc_srt_StatementGeographicalAxis_6123C8F93720A0738849BCD6B5641FBD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_SegmentGeographicalDomain" xlink:label="loc_srt_SegmentGeographicalDomain_77C6EAD2A3C6470D0E81BCD6B5640F3C_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_StatementGeographicalAxis_6123C8F93720A0738849BCD6B5641FBD" xlink:to="loc_srt_SegmentGeographicalDomain_77C6EAD2A3C6470D0E81BCD6B5640F3C_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_SegmentGeographicalDomain" xlink:label="loc_srt_SegmentGeographicalDomain_77C6EAD2A3C6470D0E81BCD6B5640F3C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_StatementGeographicalAxis_6123C8F93720A0738849BCD6B5641FBD" xlink:to="loc_srt_SegmentGeographicalDomain_77C6EAD2A3C6470D0E81BCD6B5640F3C" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/country/2017/country-2017-01-31.xsd#country_US" xlink:label="loc_country_US_72433BBD60D0CBB7CF90BCD6B5645923" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_SegmentGeographicalDomain_77C6EAD2A3C6470D0E81BCD6B5640F3C" xlink:to="loc_country_US_72433BBD60D0CBB7CF90BCD6B5645923" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_EuropeMember" xlink:label="loc_srt_EuropeMember_F3427A0EF6D569EC907CBCD6B564B976" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_SegmentGeographicalDomain_77C6EAD2A3C6470D0E81BCD6B5640F3C" xlink:to="loc_srt_EuropeMember_F3427A0EF6D569EC907CBCD6B564B976" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_LocationsExcludingTheUnitedStatesAndEuropeMember" xlink:label="loc_livn_LocationsExcludingTheUnitedStatesAndEuropeMember_DE105C5638530EF110A5BCD6B565005B" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_SegmentGeographicalDomain_77C6EAD2A3C6470D0E81BCD6B5640F3C" xlink:to="loc_livn_LocationsExcludingTheUnitedStatesAndEuropeMember_DE105C5638530EF110A5BCD6B565005B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_3B1822A475DA45DC3AA1BCD6B5652D48" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_3CAF89094F0D8CFEA520BCD6B5655D63" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_3B1822A475DA45DC3AA1BCD6B5652D48" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformationSegmentInfoDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_CDAA07A09336C60DA3FFBCD6C0E19FD0" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_6800C94EBE821A198D03BCD6C0DC770D" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_CDAA07A09336C60DA3FFBCD6C0E19FD0" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_6800C94EBE821A198D03BCD6C0DC770D" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ProductOrServiceAxis" xlink:label="loc_srt_ProductOrServiceAxis_C8B8A86A3DA06229D009BCD6C0DDF11A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_6800C94EBE821A198D03BCD6C0DC770D" xlink:to="loc_srt_ProductOrServiceAxis_C8B8A86A3DA06229D009BCD6C0DDF11A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ProductsAndServicesDomain" xlink:label="loc_srt_ProductsAndServicesDomain_50FD4F3A4E420E5A3390BCD6C0DD6E05_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ProductOrServiceAxis_C8B8A86A3DA06229D009BCD6C0DDF11A" xlink:to="loc_srt_ProductsAndServicesDomain_50FD4F3A4E420E5A3390BCD6C0DD6E05_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ProductsAndServicesDomain" xlink:label="loc_srt_ProductsAndServicesDomain_50FD4F3A4E420E5A3390BCD6C0DD6E05" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ProductOrServiceAxis_C8B8A86A3DA06229D009BCD6C0DDF11A" xlink:to="loc_srt_ProductsAndServicesDomain_50FD4F3A4E420E5A3390BCD6C0DD6E05" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_CardiopulmonaryMember" xlink:label="loc_livn_CardiopulmonaryMember_0C541EF24A80C02FF405BCD6C0DDAA22" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_50FD4F3A4E420E5A3390BCD6C0DD6E05" xlink:to="loc_livn_CardiopulmonaryMember_0C541EF24A80C02FF405BCD6C0DDAA22" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_HeartValvesMember" xlink:label="loc_livn_HeartValvesMember_97B936A873FFCD4F120ABCD6C0DD7C61" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_50FD4F3A4E420E5A3390BCD6C0DD6E05" xlink:to="loc_livn_HeartValvesMember_97B936A873FFCD4F120ABCD6C0DD7C61" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_AdvancedCirculatorySupportMember" xlink:label="loc_livn_AdvancedCirculatorySupportMember_297FFB08EDB338952C35BCD6C0DE2872" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_50FD4F3A4E420E5A3390BCD6C0DD6E05" xlink:to="loc_livn_AdvancedCirculatorySupportMember_297FFB08EDB338952C35BCD6C0DE2872" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_StatementGeographicalAxis" xlink:label="loc_srt_StatementGeographicalAxis_2355A7A81936B4FC5720BCD6C0DE27E3" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_6800C94EBE821A198D03BCD6C0DC770D" xlink:to="loc_srt_StatementGeographicalAxis_2355A7A81936B4FC5720BCD6C0DE27E3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_SegmentGeographicalDomain" xlink:label="loc_srt_SegmentGeographicalDomain_64D49AE3D2A7E1237BEBBCD6C0DEA73C_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_StatementGeographicalAxis_2355A7A81936B4FC5720BCD6C0DE27E3" xlink:to="loc_srt_SegmentGeographicalDomain_64D49AE3D2A7E1237BEBBCD6C0DEA73C_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_SegmentGeographicalDomain" xlink:label="loc_srt_SegmentGeographicalDomain_64D49AE3D2A7E1237BEBBCD6C0DEA73C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_StatementGeographicalAxis_2355A7A81936B4FC5720BCD6C0DE27E3" xlink:to="loc_srt_SegmentGeographicalDomain_64D49AE3D2A7E1237BEBBCD6C0DEA73C" xlink:type="arc" />
    <link:loc xlink:href="https://xbrl.sec.gov/country/2017/country-2017-01-31.xsd#country_US" xlink:label="loc_country_US_CD0471D7D5BCB7227353BCD6C0DEB1F6" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_SegmentGeographicalDomain_64D49AE3D2A7E1237BEBBCD6C0DEA73C" xlink:to="loc_country_US_CD0471D7D5BCB7227353BCD6C0DEB1F6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_EuropeMember" xlink:label="loc_srt_EuropeMember_29F37FF2EBE19241B712BCD6C0DFF4A7" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_SegmentGeographicalDomain_64D49AE3D2A7E1237BEBBCD6C0DEA73C" xlink:to="loc_srt_EuropeMember_29F37FF2EBE19241B712BCD6C0DFF4A7" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_LocationsExcludingTheUnitedStatesAndEuropeMember" xlink:label="loc_livn_LocationsExcludingTheUnitedStatesAndEuropeMember_D53D53327C63D3016A9FBCD6C0DF010A" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_SegmentGeographicalDomain_64D49AE3D2A7E1237BEBBCD6C0DEA73C" xlink:to="loc_livn_LocationsExcludingTheUnitedStatesAndEuropeMember_D53D53327C63D3016A9FBCD6C0DF010A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementOperatingActivitiesSegmentAxis" xlink:label="loc_us-gaap_StatementOperatingActivitiesSegmentAxis_E89291423B662BD598D3BCD6C0DFD92A" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_6800C94EBE821A198D03BCD6C0DC770D" xlink:to="loc_us-gaap_StatementOperatingActivitiesSegmentAxis_E89291423B662BD598D3BCD6C0DFD92A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentOperatingActivitiesDomain" xlink:label="loc_us-gaap_SegmentOperatingActivitiesDomain_7CDE8A6D76B39DCEFA32BCD6C0DF5BBC_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementOperatingActivitiesSegmentAxis_E89291423B662BD598D3BCD6C0DFD92A" xlink:to="loc_us-gaap_SegmentOperatingActivitiesDomain_7CDE8A6D76B39DCEFA32BCD6C0DF5BBC_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentOperatingActivitiesDomain" xlink:label="loc_us-gaap_SegmentOperatingActivitiesDomain_7CDE8A6D76B39DCEFA32BCD6C0DF5BBC" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementOperatingActivitiesSegmentAxis_E89291423B662BD598D3BCD6C0DFD92A" xlink:to="loc_us-gaap_SegmentOperatingActivitiesDomain_7CDE8A6D76B39DCEFA32BCD6C0DF5BBC" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentContinuingOperationsMember" xlink:label="loc_us-gaap_SegmentContinuingOperationsMember_F6CA95D4FAE3ACED734FBCD6C0DF3528" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentOperatingActivitiesDomain_7CDE8A6D76B39DCEFA32BCD6C0DF5BBC" xlink:to="loc_us-gaap_SegmentContinuingOperationsMember_F6CA95D4FAE3ACED734FBCD6C0DF3528" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ConsolidationItemsAxis" xlink:label="loc_srt_ConsolidationItemsAxis_AE46231803A3DC3AF7F0BCD6C0E0E931" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_6800C94EBE821A198D03BCD6C0DC770D" xlink:to="loc_srt_ConsolidationItemsAxis_AE46231803A3DC3AF7F0BCD6C0E0E931" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ConsolidationItemsDomain" xlink:label="loc_srt_ConsolidationItemsDomain_412B88E4083C439B207EBCD6C0E0EDEF_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ConsolidationItemsAxis_AE46231803A3DC3AF7F0BCD6C0E0E931" xlink:to="loc_srt_ConsolidationItemsDomain_412B88E4083C439B207EBCD6C0E0EDEF_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ConsolidationItemsDomain" xlink:label="loc_srt_ConsolidationItemsDomain_412B88E4083C439B207EBCD6C0E0EDEF" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ConsolidationItemsAxis_AE46231803A3DC3AF7F0BCD6C0E0E931" xlink:to="loc_srt_ConsolidationItemsDomain_412B88E4083C439B207EBCD6C0E0EDEF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingSegmentsMember" xlink:label="loc_us-gaap_OperatingSegmentsMember_9C6F25559A1683AAC327BCD6C0E05304" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ConsolidationItemsDomain_412B88E4083C439B207EBCD6C0E0EDEF" xlink:to="loc_us-gaap_OperatingSegmentsMember_9C6F25559A1683AAC327BCD6C0E05304" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CorporateNonSegmentMember" xlink:label="loc_us-gaap_CorporateNonSegmentMember_FB22F73678CE60FF0F1BBCD6C0E03867" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ConsolidationItemsDomain_412B88E4083C439B207EBCD6C0E0EDEF" xlink:to="loc_us-gaap_CorporateNonSegmentMember_FB22F73678CE60FF0F1BBCD6C0E03867" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_EC5F836F8BFEF8DF6752BCD6C0E003DB" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_6800C94EBE821A198D03BCD6C0DC770D" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_EC5F836F8BFEF8DF6752BCD6C0E003DB" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_8ACB22171AC7B987B9A8BCD6C0E1635C_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_EC5F836F8BFEF8DF6752BCD6C0E003DB" xlink:to="loc_us-gaap_SegmentDomain_8ACB22171AC7B987B9A8BCD6C0E1635C_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_8ACB22171AC7B987B9A8BCD6C0E1635C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_EC5F836F8BFEF8DF6752BCD6C0E003DB" xlink:to="loc_us-gaap_SegmentDomain_8ACB22171AC7B987B9A8BCD6C0E1635C" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_CardiovascularSegmentMember" xlink:label="loc_livn_CardiovascularSegmentMember_8227D41B01DB62BBA257BCD6C0E18A7A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_8ACB22171AC7B987B9A8BCD6C0E1635C" xlink:to="loc_livn_CardiovascularSegmentMember_8227D41B01DB62BBA257BCD6C0E18A7A" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_NeuromodulationSegmentMember" xlink:label="loc_livn_NeuromodulationSegmentMember_DA5917E471EDAAC72AC8BCD6C0E124CE" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_8ACB22171AC7B987B9A8BCD6C0E1635C" xlink:to="loc_livn_NeuromodulationSegmentMember_DA5917E471EDAAC72AC8BCD6C0E124CE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NumberOfReportableSegments" xlink:label="loc_us-gaap_NumberOfReportableSegments_C38D63A02B6E146EE3D5BCD6C0E1C75D" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_CDAA07A09336C60DA3FFBCD6C0E19FD0" xlink:to="loc_us-gaap_NumberOfReportableSegments_C38D63A02B6E146EE3D5BCD6C0E1C75D" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_NumberofGeographicRegionsinwhichEntityOperates" xlink:label="loc_livn_NumberofGeographicRegionsinwhichEntityOperates_2DC757DF52EA324AA633BCD6C0E2392F" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_CDAA07A09336C60DA3FFBCD6C0E19FD0" xlink:to="loc_livn_NumberofGeographicRegionsinwhichEntityOperates_2DC757DF52EA324AA633BCD6C0E2392F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_2B10B244A2FFCBE5E5F9BCD6C0E224F5" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_CDAA07A09336C60DA3FFBCD6C0E19FD0" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_2B10B244A2FFCBE5E5F9BCD6C0E224F5" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_OtherOperatingIncomeLossIncludedInSegmentIncomeLossFromContinuingOperations" xlink:label="loc_livn_OtherOperatingIncomeLossIncludedInSegmentIncomeLossFromContinuingOperations_F1604CAA0B2F80D9641DBCD6C0E284CE" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_CDAA07A09336C60DA3FFBCD6C0E19FD0" xlink:to="loc_livn_OtherOperatingIncomeLossIncludedInSegmentIncomeLossFromContinuingOperations_F1604CAA0B2F80D9641DBCD6C0E284CE" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessCombinationIntegrationRelatedCosts" xlink:label="loc_us-gaap_BusinessCombinationIntegrationRelatedCosts_E34CD091B243DA718F82BCD6C0E2D1E6" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_CDAA07A09336C60DA3FFBCD6C0E19FD0" xlink:to="loc_us-gaap_BusinessCombinationIntegrationRelatedCosts_E34CD091B243DA718F82BCD6C0E2D1E6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_A92C6988A34D06323234BCD6C0E236D1" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_CDAA07A09336C60DA3FFBCD6C0E19FD0" xlink:to="loc_us-gaap_RestructuringCharges_A92C6988A34D06323234BCD6C0E236D1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_C414A7C9D08498E021A7BCD6C0E3AB3C" xlink:type="locator" />
    <link:definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_CDAA07A09336C60DA3FFBCD6C0E19FD0" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_C414A7C9D08498E021A7BCD6C0E3AB3C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingIncomeLoss" xlink:label="loc_us-gaap_OperatingIncomeLoss_09E0FDCDF1D350BA6ADFBCD6C0E385F2" xlink:type="locator" />
    <link:definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_CDAA07A09336C60DA3FFBCD6C0E19FD0" xlink:to="loc_us-gaap_OperatingIncomeLoss_09E0FDCDF1D350BA6ADFBCD6C0E385F2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InvestmentIncomeInterest" xlink:label="loc_us-gaap_InvestmentIncomeInterest_D2742940935776A303FABCD6C0E3E42F" xlink:type="locator" />
    <link:definitionArc order="9" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_CDAA07A09336C60DA3FFBCD6C0E19FD0" xlink:to="loc_us-gaap_InvestmentIncomeInterest_D2742940935776A303FABCD6C0E3E42F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InterestExpense" xlink:label="loc_us-gaap_InterestExpense_F38D4DA9BDC28A58F0C1BCD6C0E3E0DA" xlink:type="locator" />
    <link:definitionArc order="10" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_CDAA07A09336C60DA3FFBCD6C0E19FD0" xlink:to="loc_us-gaap_InterestExpense_F38D4DA9BDC28A58F0C1BCD6C0E3E0DA" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_ForeignCurrencyTransactionGainLossandOtherNonoperatingIncome" xlink:label="loc_livn_ForeignCurrencyTransactionGainLossandOtherNonoperatingIncome_1B89C9CB03AA233D9167BCD6C0E3C03E" xlink:type="locator" />
    <link:definitionArc order="11" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_CDAA07A09336C60DA3FFBCD6C0E19FD0" xlink:to="loc_livn_ForeignCurrencyTransactionGainLossandOtherNonoperatingIncome_1B89C9CB03AA233D9167BCD6C0E3C03E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_C73B02BFC977A52ADBF6BCD6C0E3D72A" xlink:type="locator" />
    <link:definitionArc order="12" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_CDAA07A09336C60DA3FFBCD6C0E19FD0" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_C73B02BFC977A52ADBF6BCD6C0E3D72A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_Assets" xlink:label="loc_us-gaap_Assets_D02E9F0241515975EAAABCD6C0E4986E" xlink:type="locator" />
    <link:definitionArc order="13" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_CDAA07A09336C60DA3FFBCD6C0E19FD0" xlink:to="loc_us-gaap_Assets_D02E9F0241515975EAAABCD6C0E4986E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PropertyPlantAndEquipmentAdditions" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAdditions_7A8793AE9D9696BA2918BCD6C0E42CEA" xlink:type="locator" />
    <link:definitionArc order="14" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_CDAA07A09336C60DA3FFBCD6C0E19FD0" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentAdditions_7A8793AE9D9696BA2918BCD6C0E42CEA" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/GeographicAndSegmentInformationTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/IncomeTaxes" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/IncomeTaxesNarrativeDetails" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/Investments" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/InvestmentsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfEquityMethodInvestmentsLineItems" xlink:label="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_D4A8251A8F74472BB49FBCD6E54F375A" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfCostMethodInvestmentsTable" xlink:label="loc_us-gaap_ScheduleOfCostMethodInvestmentsTable_EB7E65004D5E8E5C1D7CBCD6E549145E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_D4A8251A8F74472BB49FBCD6E54F375A" xlink:to="loc_us-gaap_ScheduleOfCostMethodInvestmentsTable_EB7E65004D5E8E5C1D7CBCD6E549145E" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis" xlink:label="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_A1FFF18FFDF9780B1418BCD6E54A731D" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfCostMethodInvestmentsTable_EB7E65004D5E8E5C1D7CBCD6E549145E" xlink:to="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_A1FFF18FFDF9780B1418BCD6E54A731D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_EquityMethodInvesteeNameDomain" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_D2AE63C79035CDA11A6CBCD6E54AD8EB_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_A1FFF18FFDF9780B1418BCD6E54A731D" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_D2AE63C79035CDA11A6CBCD6E54AD8EB_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_EquityMethodInvesteeNameDomain" xlink:label="loc_srt_EquityMethodInvesteeNameDomain_D2AE63C79035CDA11A6CBCD6E54AD8EB" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis_A1FFF18FFDF9780B1418BCD6E54A731D" xlink:to="loc_srt_EquityMethodInvesteeNameDomain_D2AE63C79035CDA11A6CBCD6E54AD8EB" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_RespicardiaMember" xlink:label="loc_livn_RespicardiaMember_1A1D67E6C9A9C07EF8CABCD6E54A1170" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_D2AE63C79035CDA11A6CBCD6E54AD8EB" xlink:to="loc_livn_RespicardiaMember_1A1D67E6C9A9C07EF8CABCD6E54A1170" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_ALungTechnologiesInc.Member" xlink:label="loc_livn_ALungTechnologiesInc.Member_7B89FBA10D406885EFE9BCD6E54ACFC6" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_D2AE63C79035CDA11A6CBCD6E54AD8EB" xlink:to="loc_livn_ALungTechnologiesInc.Member_7B89FBA10D406885EFE9BCD6E54ACFC6" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_CeribellInc.Member" xlink:label="loc_livn_CeribellInc.Member_EEFAB39A0452B0498E13BCD6E54A481B" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_D2AE63C79035CDA11A6CBCD6E54AD8EB" xlink:to="loc_livn_CeribellInc.Member_EEFAB39A0452B0498E13BCD6E54A481B" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_ShiraTronicsInc.Member" xlink:label="loc_livn_ShiraTronicsInc.Member_206168F646F60ACDB7F0BCD6E54B7009" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_D2AE63C79035CDA11A6CBCD6E54AD8EB" xlink:to="loc_livn_ShiraTronicsInc.Member_206168F646F60ACDB7F0BCD6E54B7009" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_RainbowMedicalLtd.Member" xlink:label="loc_livn_RainbowMedicalLtd.Member_4A23696BB925AA8E2088BCD6E54BDD39" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_D2AE63C79035CDA11A6CBCD6E54AD8EB" xlink:to="loc_livn_RainbowMedicalLtd.Member_4A23696BB925AA8E2088BCD6E54BDD39" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_MDStartIIMember" xlink:label="loc_livn_MDStartIIMember_912CE2750D6EA7E85AF4BCD6E54B2A4E" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_D2AE63C79035CDA11A6CBCD6E54AD8EB" xlink:to="loc_livn_MDStartIIMember_912CE2750D6EA7E85AF4BCD6E54B2A4E" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_HighlifeS.A.S.Member" xlink:label="loc_livn_HighlifeS.A.S.Member_3CC188A6E2E08BCE37E3BCD6E54B3A12" xlink:type="locator" />
    <link:definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_D2AE63C79035CDA11A6CBCD6E54AD8EB" xlink:to="loc_livn_HighlifeS.A.S.Member_3CC188A6E2E08BCE37E3BCD6E54B3A12" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_OtherMember" xlink:label="loc_livn_OtherMember_29951F6BE6941A1FF150BCD6E54B3989" xlink:type="locator" />
    <link:definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_EquityMethodInvesteeNameDomain_D2AE63C79035CDA11A6CBCD6E54AD8EB" xlink:to="loc_livn_OtherMember_29951F6BE6941A1FF150BCD6E54B3989" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RelatedPartyTransactionAxis" xlink:label="loc_us-gaap_RelatedPartyTransactionAxis_75C33847EC04CA525D51BCD6E54BA903" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfCostMethodInvestmentsTable_EB7E65004D5E8E5C1D7CBCD6E549145E" xlink:to="loc_us-gaap_RelatedPartyTransactionAxis_75C33847EC04CA525D51BCD6E54BA903" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RelatedPartyTransactionDomain" xlink:label="loc_us-gaap_RelatedPartyTransactionDomain_949C81CFB583269AC3D6BCD6E54CB25B_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RelatedPartyTransactionAxis_75C33847EC04CA525D51BCD6E54BA903" xlink:to="loc_us-gaap_RelatedPartyTransactionDomain_949C81CFB583269AC3D6BCD6E54CB25B_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RelatedPartyTransactionDomain" xlink:label="loc_us-gaap_RelatedPartyTransactionDomain_949C81CFB583269AC3D6BCD6E54CB25B" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RelatedPartyTransactionAxis_75C33847EC04CA525D51BCD6E54BA903" xlink:to="loc_us-gaap_RelatedPartyTransactionDomain_949C81CFB583269AC3D6BCD6E54CB25B" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_CostMethodInvesteeMember" xlink:label="loc_livn_CostMethodInvesteeMember_3DCC3E73BFB48E7AE4F9BCD6E54C175E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_949C81CFB583269AC3D6BCD6E54CB25B" xlink:to="loc_livn_CostMethodInvesteeMember_3DCC3E73BFB48E7AE4F9BCD6E54C175E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_CounterpartyNameAxis" xlink:label="loc_srt_CounterpartyNameAxis_03B209847659DADF39FBBCD6E54CE4F2" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfCostMethodInvestmentsTable_EB7E65004D5E8E5C1D7CBCD6E549145E" xlink:to="loc_srt_CounterpartyNameAxis_03B209847659DADF39FBBCD6E54CE4F2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_C821A7ADCE7A9793A3E3BCD6E54CD0CA_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_CounterpartyNameAxis_03B209847659DADF39FBBCD6E54CE4F2" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_C821A7ADCE7A9793A3E3BCD6E54CD0CA_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_RepurchaseAgreementCounterpartyNameDomain" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_C821A7ADCE7A9793A3E3BCD6E54CD0CA" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_CounterpartyNameAxis_03B209847659DADF39FBBCD6E54CE4F2" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_C821A7ADCE7A9793A3E3BCD6E54CD0CA" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_RespicardiaMember" xlink:label="loc_livn_RespicardiaMember_3D6DA1EF2A3A0B92160BBCD6E54DB3EA" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_C821A7ADCE7A9793A3E3BCD6E54CD0CA" xlink:to="loc_livn_RespicardiaMember_3D6DA1EF2A3A0B92160BBCD6E54DB3EA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis" xlink:label="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_B613C6ABF8BCD11D5179BCD6E54DF2B8" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfCostMethodInvestmentsTable_EB7E65004D5E8E5C1D7CBCD6E549145E" xlink:to="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_B613C6ABF8BCD11D5179BCD6E54DF2B8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RelatedPartyDomain" xlink:label="loc_us-gaap_RelatedPartyDomain_9586530FEE010E916B6DBCD6E54D2FDB_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_B613C6ABF8BCD11D5179BCD6E54DF2B8" xlink:to="loc_us-gaap_RelatedPartyDomain_9586530FEE010E916B6DBCD6E54D2FDB_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RelatedPartyDomain" xlink:label="loc_us-gaap_RelatedPartyDomain_9586530FEE010E916B6DBCD6E54D2FDB" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_B613C6ABF8BCD11D5179BCD6E54DF2B8" xlink:to="loc_us-gaap_RelatedPartyDomain_9586530FEE010E916B6DBCD6E54D2FDB" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_CostMethodInvesteeMember" xlink:label="loc_livn_CostMethodInvesteeMember_B6062176B44FF5114027BCD6E54E58B4" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RelatedPartyDomain_9586530FEE010E916B6DBCD6E54D2FDB" xlink:to="loc_livn_CostMethodInvesteeMember_B6062176B44FF5114027BCD6E54E58B4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BalanceSheetLocationAxis" xlink:label="loc_us-gaap_BalanceSheetLocationAxis_8180EDB7E60E9D4CBFC7BCD6E54E501B" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfCostMethodInvestmentsTable_EB7E65004D5E8E5C1D7CBCD6E549145E" xlink:to="loc_us-gaap_BalanceSheetLocationAxis_8180EDB7E60E9D4CBFC7BCD6E54E501B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BalanceSheetLocationDomain" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_761FF03AE5DFCDA36D7BBCD6E54EEF7B_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_8180EDB7E60E9D4CBFC7BCD6E54E501B" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_761FF03AE5DFCDA36D7BBCD6E54EEF7B_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BalanceSheetLocationDomain" xlink:label="loc_us-gaap_BalanceSheetLocationDomain_761FF03AE5DFCDA36D7BBCD6E54EEF7B" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BalanceSheetLocationAxis_8180EDB7E60E9D4CBFC7BCD6E54E501B" xlink:to="loc_us-gaap_BalanceSheetLocationDomain_761FF03AE5DFCDA36D7BBCD6E54EEF7B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PrepaidExpensesAndOtherCurrentAssetsMember" xlink:label="loc_us-gaap_PrepaidExpensesAndOtherCurrentAssetsMember_83E3B75CFB2BFFD8A650BCD6E54E9908" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BalanceSheetLocationDomain_761FF03AE5DFCDA36D7BBCD6E54EEF7B" xlink:to="loc_us-gaap_PrepaidExpensesAndOtherCurrentAssetsMember_83E3B75CFB2BFFD8A650BCD6E54E9908" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount" xlink:label="loc_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount_AC68D44710799A485AA6BCD6E54FBD42" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_D4A8251A8F74472BB49FBCD6E54F375A" xlink:to="loc_us-gaap_EquitySecuritiesWithoutReadilyDeterminableFairValueAmount_AC68D44710799A485AA6BCD6E54FBD42" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityMethodInvestments" xlink:label="loc_us-gaap_EquityMethodInvestments_FA4DA7E65E88E81E20C7BCD6E54F8AB2" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_D4A8251A8F74472BB49FBCD6E54F375A" xlink:to="loc_us-gaap_EquityMethodInvestments_FA4DA7E65E88E81E20C7BCD6E54F8AB2" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquitySecuritiesFvNiAndWithoutReadilyDeterminableFairValue" xlink:label="loc_us-gaap_EquitySecuritiesFvNiAndWithoutReadilyDeterminableFairValue_3AB2CC4300409466A178BCD6E54F4223" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_D4A8251A8F74472BB49FBCD6E54F375A" xlink:to="loc_us-gaap_EquitySecuritiesFvNiAndWithoutReadilyDeterminableFairValue_3AB2CC4300409466A178BCD6E54F4223" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NotesReceivableNet" xlink:label="loc_us-gaap_NotesReceivableNet_E107906778C57C1F223DBCD6E54F2EA1" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ScheduleOfEquityMethodInvestmentsLineItems_D4A8251A8F74472BB49FBCD6E54F375A" xlink:to="loc_us-gaap_NotesReceivableNet_E107906778C57C1F223DBCD6E54F2EA1" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/InvestmentsTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/NewAccountingPronouncements" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/NewAccountingPronouncementsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems" xlink:label="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_1156ADA10E467B84FD74BCD6E46ED618" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable" xlink:label="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_B6F2108A6BB50C3961F2BCD6E46CD184" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_1156ADA10E467B84FD74BCD6E46ED618" xlink:to="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_B6F2108A6BB50C3961F2BCD6E46CD184" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_5FF034B7BBC89A5C1143BCD6E46C4D28" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_B6F2108A6BB50C3961F2BCD6E46CD184" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_5FF034B7BBC89A5C1143BCD6E46C4D28" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_324DBDABEF14D521B52EBCD6E46CA1DD_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_5FF034B7BBC89A5C1143BCD6E46C4D28" xlink:to="loc_us-gaap_EquityComponentDomain_324DBDABEF14D521B52EBCD6E46CA1DD_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_324DBDABEF14D521B52EBCD6E46CA1DD" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_5FF034B7BBC89A5C1143BCD6E46C4D28" xlink:to="loc_us-gaap_EquityComponentDomain_324DBDABEF14D521B52EBCD6E46CA1DD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RetainedEarningsMember" xlink:label="loc_us-gaap_RetainedEarningsMember_75602E7F2D6C29227585BCD6E46DC504" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_324DBDABEF14D521B52EBCD6E46CA1DD" xlink:to="loc_us-gaap_RetainedEarningsMember_75602E7F2D6C29227585BCD6E46DC504" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdjustmentsForNewAccountingPronouncementsAxis" xlink:label="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_9A91F8C0F24BE04B5860BCD6E46DD41C" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_B6F2108A6BB50C3961F2BCD6E46CD184" xlink:to="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_9A91F8C0F24BE04B5860BCD6E46DD41C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TypeOfAdoptionMember" xlink:label="loc_us-gaap_TypeOfAdoptionMember_A67A95EAC0B1DBD90E20BCD6E46D2FC6_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_9A91F8C0F24BE04B5860BCD6E46DD41C" xlink:to="loc_us-gaap_TypeOfAdoptionMember_A67A95EAC0B1DBD90E20BCD6E46D2FC6_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TypeOfAdoptionMember" xlink:label="loc_us-gaap_TypeOfAdoptionMember_A67A95EAC0B1DBD90E20BCD6E46D2FC6" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_9A91F8C0F24BE04B5860BCD6E46DD41C" xlink:to="loc_us-gaap_TypeOfAdoptionMember_A67A95EAC0B1DBD90E20BCD6E46D2FC6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountingStandardsUpdate201613Member" xlink:label="loc_us-gaap_AccountingStandardsUpdate201613Member_F9E5985C032C67BE3473BCD6E46D68F5" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TypeOfAdoptionMember_A67A95EAC0B1DBD90E20BCD6E46D2FC6" xlink:to="loc_us-gaap_AccountingStandardsUpdate201613Member_F9E5985C032C67BE3473BCD6E46D68F5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccountsReceivableNetCurrent" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_28F16B3CFCDCBBC0FB63BCD6E46E1EB4" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_1156ADA10E467B84FD74BCD6E46ED618" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_28F16B3CFCDCBBC0FB63BCD6E46E1EB4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CumulativeEffectOfNewAccountingPrincipleInPeriodOfAdoption" xlink:label="loc_us-gaap_CumulativeEffectOfNewAccountingPrincipleInPeriodOfAdoption_B85FF9AB1AC1D12F00CCBCD6E46E97AE" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_1156ADA10E467B84FD74BCD6E46ED618" xlink:to="loc_us-gaap_CumulativeEffectOfNewAccountingPrincipleInPeriodOfAdoption_B85FF9AB1AC1D12F00CCBCD6E46E97AE" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/NewAccountingPronouncementsTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/ProductRemediationLiability" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/ProductRemediationLiabilityDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProductLiabilityContingencyLineItems" xlink:label="loc_us-gaap_ProductLiabilityContingencyLineItems_6E1286D2DD521F0A1F76BD77D6A8743F" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ProductLiabilityContingencyTable" xlink:label="loc_us-gaap_ProductLiabilityContingencyTable_CF63ED34B79FC797F47DBD77D6A7A3D0" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ProductLiabilityContingencyLineItems_6E1286D2DD521F0A1F76BD77D6A8743F" xlink:to="loc_us-gaap_ProductLiabilityContingencyTable_CF63ED34B79FC797F47DBD77D6A7A3D0" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_LitigationCaseAxis" xlink:label="loc_srt_LitigationCaseAxis_3C0EA731F2E710354493BD77D6A7B325" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ProductLiabilityContingencyTable_CF63ED34B79FC797F47DBD77D6A7A3D0" xlink:to="loc_srt_LitigationCaseAxis_3C0EA731F2E710354493BD77D6A7B325" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="loc_srt_LitigationCaseTypeDomain_DDA2E3443FD6B4688FABBD77D6A71B2A_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_LitigationCaseAxis_3C0EA731F2E710354493BD77D6A7B325" xlink:to="loc_srt_LitigationCaseTypeDomain_DDA2E3443FD6B4688FABBD77D6A71B2A_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_LitigationCaseTypeDomain" xlink:label="loc_srt_LitigationCaseTypeDomain_DDA2E3443FD6B4688FABBD77D6A71B2A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_LitigationCaseAxis_3C0EA731F2E710354493BD77D6A7B325" xlink:to="loc_srt_LitigationCaseTypeDomain_DDA2E3443FD6B4688FABBD77D6A71B2A" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_ProductLiabilityMember" xlink:label="loc_livn_ProductLiabilityMember_16D782747A2F0B603EEBBD77D6A70EF1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_LitigationCaseTypeDomain_DDA2E3443FD6B4688FABBD77D6A71B2A" xlink:to="loc_livn_ProductLiabilityMember_16D782747A2F0B603EEBBD77D6A70EF1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LossContingencyAccrualAtCarryingValue" xlink:label="loc_us-gaap_LossContingencyAccrualAtCarryingValue_926E7A1B1E7EFCA6CDC1BD77D6A858C1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ProductLiabilityContingencyLineItems_6E1286D2DD521F0A1F76BD77D6A8743F" xlink:to="loc_us-gaap_LossContingencyAccrualAtCarryingValue_926E7A1B1E7EFCA6CDC1BD77D6A858C1" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/ProductRemediationLiabilityTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/Restructuring" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/RestructuringRestructuringAndRelatedCostsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="loc_us-gaap_RestructuringCostAndReserveLineItems_E823AB1E58AB2A152E33BCD6E569BEE0" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_AF47DA496BB58269773DBCD6E567A500" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_E823AB1E58AB2A152E33BCD6E569BEE0" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_AF47DA496BB58269773DBCD6E567A500" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringPlanAxis" xlink:label="loc_us-gaap_RestructuringPlanAxis_0297AEF857890C6E30A7BCD6E5677DBA" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_AF47DA496BB58269773DBCD6E567A500" xlink:to="loc_us-gaap_RestructuringPlanAxis_0297AEF857890C6E30A7BCD6E5677DBA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringPlanDomain" xlink:label="loc_us-gaap_RestructuringPlanDomain_EB1C1096ED99F804BD05BCD6E568AA8C_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RestructuringPlanAxis_0297AEF857890C6E30A7BCD6E5677DBA" xlink:to="loc_us-gaap_RestructuringPlanDomain_EB1C1096ED99F804BD05BCD6E568AA8C_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringPlanDomain" xlink:label="loc_us-gaap_RestructuringPlanDomain_EB1C1096ED99F804BD05BCD6E568AA8C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RestructuringPlanAxis_0297AEF857890C6E30A7BCD6E5677DBA" xlink:to="loc_us-gaap_RestructuringPlanDomain_EB1C1096ED99F804BD05BCD6E568AA8C" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_ReorganizationPlansMember" xlink:label="loc_livn_ReorganizationPlansMember_433A4D31E75B58438BDABCD6E568E28E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringPlanDomain_EB1C1096ED99F804BD05BCD6E568AA8C" xlink:to="loc_livn_ReorganizationPlansMember_433A4D31E75B58438BDABCD6E568E28E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCostAndReserveAxis" xlink:label="loc_us-gaap_RestructuringCostAndReserveAxis_975E5E08A40F1A041FABBCD6E5680F67" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_AF47DA496BB58269773DBCD6E567A500" xlink:to="loc_us-gaap_RestructuringCostAndReserveAxis_975E5E08A40F1A041FABBCD6E5680F67" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="loc_us-gaap_TypeOfRestructuringDomain_02028F059FC1C44E5CE8BCD6E5689C44_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_RestructuringCostAndReserveAxis_975E5E08A40F1A041FABBCD6E5680F67" xlink:to="loc_us-gaap_TypeOfRestructuringDomain_02028F059FC1C44E5CE8BCD6E5689C44_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TypeOfRestructuringDomain" xlink:label="loc_us-gaap_TypeOfRestructuringDomain_02028F059FC1C44E5CE8BCD6E5689C44" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_RestructuringCostAndReserveAxis_975E5E08A40F1A041FABBCD6E5680F67" xlink:to="loc_us-gaap_TypeOfRestructuringDomain_02028F059FC1C44E5CE8BCD6E5689C44" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EmployeeSeveranceMember" xlink:label="loc_us-gaap_EmployeeSeveranceMember_3D9B5B62A3E2F07FF836BCD6E569D551" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_02028F059FC1C44E5CE8BCD6E5689C44" xlink:to="loc_us-gaap_EmployeeSeveranceMember_3D9B5B62A3E2F07FF836BCD6E569D551" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherRestructuringMember" xlink:label="loc_us-gaap_OtherRestructuringMember_DC5661C9EAC4B7C4A482BCD6E569EFA6" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_TypeOfRestructuringDomain_02028F059FC1C44E5CE8BCD6E5689C44" xlink:to="loc_us-gaap_OtherRestructuringMember_DC5661C9EAC4B7C4A482BCD6E569EFA6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringReserveRollForward" xlink:label="loc_us-gaap_RestructuringReserveRollForward_3C74B3653BE05405C807BCD6E5696E38" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_E823AB1E58AB2A152E33BCD6E569BEE0" xlink:to="loc_us-gaap_RestructuringReserveRollForward_3C74B3653BE05405C807BCD6E5696E38" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringReserve" xlink:label="loc_us-gaap_RestructuringReserve_3FAEED413C7480563779BCD6E56A090D" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringReserveRollForward_3C74B3653BE05405C807BCD6E5696E38" xlink:to="loc_us-gaap_RestructuringReserve_3FAEED413C7480563779BCD6E56A090D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_FD13C72A67A1CB7ADA3ABCD6E56A05D1" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringReserveRollForward_3C74B3653BE05405C807BCD6E5696E38" xlink:to="loc_us-gaap_RestructuringCharges_FD13C72A67A1CB7ADA3ABCD6E56A05D1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_PaymentsForRestructuring" xlink:label="loc_us-gaap_PaymentsForRestructuring_0D4B7F249D39C13C7179BCD6E56ACC74" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringReserveRollForward_3C74B3653BE05405C807BCD6E5696E38" xlink:to="loc_us-gaap_PaymentsForRestructuring_0D4B7F249D39C13C7179BCD6E56ACC74" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringAndRelatedCostCostIncurredToDate1" xlink:label="loc_us-gaap_RestructuringAndRelatedCostCostIncurredToDate1_C09E30403A38EC53CE97BCD6E56AE700" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_E823AB1E58AB2A152E33BCD6E569BEE0" xlink:to="loc_us-gaap_RestructuringAndRelatedCostCostIncurredToDate1_C09E30403A38EC53CE97BCD6E56AE700" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/RestructuringRestructuringExpenseBySegmentDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCostAndReserveLineItems" xlink:label="loc_us-gaap_RestructuringCostAndReserveLineItems_8B96A63AE90F17AEE15BBCD6E5636996" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfRestructuringAndRelatedCostsTable" xlink:label="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_D705DE2F02F2BF0C68B0BCD6E561322A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_8B96A63AE90F17AEE15BBCD6E5636996" xlink:to="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_D705DE2F02F2BF0C68B0BCD6E561322A" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ConsolidationItemsAxis" xlink:label="loc_srt_ConsolidationItemsAxis_BC5F0E88FC8DA5621433BCD6E5629041" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_D705DE2F02F2BF0C68B0BCD6E561322A" xlink:to="loc_srt_ConsolidationItemsAxis_BC5F0E88FC8DA5621433BCD6E5629041" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ConsolidationItemsDomain" xlink:label="loc_srt_ConsolidationItemsDomain_BFB036EBB9639AA82DF2BCD6E5624225_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ConsolidationItemsAxis_BC5F0E88FC8DA5621433BCD6E5629041" xlink:to="loc_srt_ConsolidationItemsDomain_BFB036EBB9639AA82DF2BCD6E5624225_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/srt/2019/elts/srt-2019-01-31.xsd#srt_ConsolidationItemsDomain" xlink:label="loc_srt_ConsolidationItemsDomain_BFB036EBB9639AA82DF2BCD6E5624225" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ConsolidationItemsAxis_BC5F0E88FC8DA5621433BCD6E5629041" xlink:to="loc_srt_ConsolidationItemsDomain_BFB036EBB9639AA82DF2BCD6E5624225" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingSegmentsMember" xlink:label="loc_us-gaap_OperatingSegmentsMember_36E53066B9037C01D0ADBCD6E562D8CD" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ConsolidationItemsDomain_BFB036EBB9639AA82DF2BCD6E5624225" xlink:to="loc_us-gaap_OperatingSegmentsMember_36E53066B9037C01D0ADBCD6E562D8CD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CorporateNonSegmentMember" xlink:label="loc_us-gaap_CorporateNonSegmentMember_4DF9D65D451D3CC697D8BCD6E562D4A0" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ConsolidationItemsDomain_BFB036EBB9639AA82DF2BCD6E5624225" xlink:to="loc_us-gaap_CorporateNonSegmentMember_4DF9D65D451D3CC697D8BCD6E562D4A0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_F6322248B88D88005C49BCD6E563D547" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfRestructuringAndRelatedCostsTable_D705DE2F02F2BF0C68B0BCD6E561322A" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_F6322248B88D88005C49BCD6E563D547" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_692C2E7FA749E5F10368BCD6E5637B6C_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_F6322248B88D88005C49BCD6E563D547" xlink:to="loc_us-gaap_SegmentDomain_692C2E7FA749E5F10368BCD6E5637B6C_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_692C2E7FA749E5F10368BCD6E5637B6C" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_F6322248B88D88005C49BCD6E563D547" xlink:to="loc_us-gaap_SegmentDomain_692C2E7FA749E5F10368BCD6E5637B6C" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_CardiovascularSegmentMember" xlink:label="loc_livn_CardiovascularSegmentMember_868520D4B212896E2D36BCD6E5632032" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_692C2E7FA749E5F10368BCD6E5637B6C" xlink:to="loc_livn_CardiovascularSegmentMember_868520D4B212896E2D36BCD6E5632032" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_NeuromodulationSegmentMember" xlink:label="loc_livn_NeuromodulationSegmentMember_9DAB0D273BE28412420FBCD6E5636731" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_692C2E7FA749E5F10368BCD6E5637B6C" xlink:to="loc_livn_NeuromodulationSegmentMember_9DAB0D273BE28412420FBCD6E5636731" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestructuringCharges" xlink:label="loc_us-gaap_RestructuringCharges_6E9B15AE4C5A6D3531D6BCD6E56467F7" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RestructuringCostAndReserveLineItems_8B96A63AE90F17AEE15BBCD6E5636996" xlink:to="loc_us-gaap_RestructuringCharges_6E9B15AE4C5A6D3531D6BCD6E56467F7" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/RestructuringTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/StockBasedIncentivePlans" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/StockBasedIncentivePlansCompensationExpenseDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_404AD405C24B5C6F16C8BCD6E4B9874A" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_361ECD822EC2D057F22DBCD6E4B78E9F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_404AD405C24B5C6F16C8BCD6E4B9874A" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_361ECD822EC2D057F22DBCD6E4B78E9F" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_3C97CE96A1347FB3C041BCD6E4B896BD" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_361ECD822EC2D057F22DBCD6E4B78E9F" xlink:to="loc_us-gaap_AwardTypeAxis_3C97CE96A1347FB3C041BCD6E4B896BD" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_CBF011E4DB3678433EF4BCD6E4B8F321_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_AwardTypeAxis_3C97CE96A1347FB3C041BCD6E4B896BD" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_CBF011E4DB3678433EF4BCD6E4B8F321_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_CBF011E4DB3678433EF4BCD6E4B8F321" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_AwardTypeAxis_3C97CE96A1347FB3C041BCD6E4B896BD" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_CBF011E4DB3678433EF4BCD6E4B8F321" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestrictedStockUnitsRSUMember" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_5FA88DBD5DF50C8402EDBCD6E4B8E3CA" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_CBF011E4DB3678433EF4BCD6E4B8F321" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_5FA88DBD5DF50C8402EDBCD6E4B8E3CA" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockAppreciationRightsSARSMember" xlink:label="loc_us-gaap_StockAppreciationRightsSARSMember_D3DF955A05F5515F26A8BCD6E4B9CC80" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_CBF011E4DB3678433EF4BCD6E4B8F321" xlink:to="loc_us-gaap_StockAppreciationRightsSARSMember_D3DF955A05F5515F26A8BCD6E4B9CC80" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_MarketbasedPerformanceRestrictedStockUnitMember" xlink:label="loc_livn_MarketbasedPerformanceRestrictedStockUnitMember_DC932FDA641E4E77E634BCD6E4B958AB" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_CBF011E4DB3678433EF4BCD6E4B8F321" xlink:to="loc_livn_MarketbasedPerformanceRestrictedStockUnitMember_DC932FDA641E4E77E634BCD6E4B958AB" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_OperatingPerformancebasedRestrictedStockUnitsMember" xlink:label="loc_livn_OperatingPerformancebasedRestrictedStockUnitsMember_A3F9B2025FE7CBB41F12BCD6E4B9BF8B" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_CBF011E4DB3678433EF4BCD6E4B8F321" xlink:to="loc_livn_OperatingPerformancebasedRestrictedStockUnitsMember_A3F9B2025FE7CBB41F12BCD6E4B9BF8B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EmployeeStockOptionMember" xlink:label="loc_us-gaap_EmployeeStockOptionMember_D10F0DF658DB7D8ABFF6BCD6E4B979D9" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_CBF011E4DB3678433EF4BCD6E4B8F321" xlink:to="loc_us-gaap_EmployeeStockOptionMember_D10F0DF658DB7D8ABFF6BCD6E4B979D9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AllocatedShareBasedCompensationExpense" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_BBC563142CC7304F1E1EBCD6E4B907D1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_404AD405C24B5C6F16C8BCD6E4B9874A" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_BBC563142CC7304F1E1EBCD6E4B907D1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_BF5BF3E4BC27B89FBE8CBCD6E4BAC8F3" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_404AD405C24B5C6F16C8BCD6E4B9874A" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_BF5BF3E4BC27B89FBE8CBCD6E4BAC8F3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardCompensationCost1" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardCompensationCost1_06922F0B5DAEEBC3090FBCD6E4BA6FAC" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_404AD405C24B5C6F16C8BCD6E4B9874A" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardCompensationCost1_06922F0B5DAEEBC3090FBCD6E4BA6FAC" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/StockBasedIncentivePlansExecutedAgreementsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1B3526713CDEBFF0BB51BCD6E4B4E34C" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_655FD1DD50439FB84E6DBCD6E4B2BC21" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1B3526713CDEBFF0BB51BCD6E4B4E34C" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_655FD1DD50439FB84E6DBCD6E4B2BC21" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="loc_us-gaap_AwardTypeAxis_71608CEF61B6CC6EB33CBCD6E4B3DE82" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_655FD1DD50439FB84E6DBCD6E4B2BC21" xlink:to="loc_us-gaap_AwardTypeAxis_71608CEF61B6CC6EB33CBCD6E4B3DE82" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0EC2D10E20F96FE8DFCBBCD6E4B3E0F3_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_AwardTypeAxis_71608CEF61B6CC6EB33CBCD6E4B3DE82" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0EC2D10E20F96FE8DFCBBCD6E4B3E0F3_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0EC2D10E20F96FE8DFCBBCD6E4B3E0F3" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_AwardTypeAxis_71608CEF61B6CC6EB33CBCD6E4B3DE82" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0EC2D10E20F96FE8DFCBBCD6E4B3E0F3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockAppreciationRightsSARSMember" xlink:label="loc_us-gaap_StockAppreciationRightsSARSMember_B9D60ED5549660953C28BCD6E4B3CD19" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0EC2D10E20F96FE8DFCBBCD6E4B3E0F3" xlink:to="loc_us-gaap_StockAppreciationRightsSARSMember_B9D60ED5549660953C28BCD6E4B3CD19" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RestrictedStockUnitsRSUMember" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_B09163E53A923F7B38ACBCD6E4B48700" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0EC2D10E20F96FE8DFCBBCD6E4B3E0F3" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_B09163E53A923F7B38ACBCD6E4B48700" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_MarketbasedPerformanceRestrictedStockUnitMember" xlink:label="loc_livn_MarketbasedPerformanceRestrictedStockUnitMember_E7B6C89DE90D7B3C8BEFBCD6E4B4C90B" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0EC2D10E20F96FE8DFCBBCD6E4B3E0F3" xlink:to="loc_livn_MarketbasedPerformanceRestrictedStockUnitMember_E7B6C89DE90D7B3C8BEFBCD6E4B4C90B" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_OperatingPerformancebasedRestrictedStockUnitsMember" xlink:label="loc_livn_OperatingPerformancebasedRestrictedStockUnitsMember_2D8D317DB221CDCD6ED3BCD6E4B46488" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0EC2D10E20F96FE8DFCBBCD6E4B3E0F3" xlink:to="loc_livn_OperatingPerformancebasedRestrictedStockUnitsMember_2D8D317DB221CDCD6ED3BCD6E4B46488" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_F4107063DD68EE2F3EF1BCD6E4B42DD1" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1B3526713CDEBFF0BB51BCD6E4B4E34C" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_F4107063DD68EE2F3EF1BCD6E4B42DD1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_2E8B507445FC3D5273F2BCD6E4B4EC4B" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_1B3526713CDEBFF0BB51BCD6E4B4E34C" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_2E8B507445FC3D5273F2BCD6E4B4EC4B" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/StockBasedIncentivePlansTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/StockholdersEquity" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/StockholdersEquityComprehensiveIncomeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_0CF5F13DFB4A0310C77EBCC086289FB4" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossTable" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_F3EBAD468E4FAE5BE236BCC0862602F5" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_0CF5F13DFB4A0310C77EBCC086289FB4" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_F3EBAD468E4FAE5BE236BCC0862602F5" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_7E4AC40F9A5A28A58079BCC08626536D" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_F3EBAD468E4FAE5BE236BCC0862602F5" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_7E4AC40F9A5A28A58079BCC08626536D" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_77E70C9826A7B25F7BBEBCC086279444_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_7E4AC40F9A5A28A58079BCC08626536D" xlink:to="loc_us-gaap_EquityComponentDomain_77E70C9826A7B25F7BBEBCC086279444_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_77E70C9826A7B25F7BBEBCC086279444" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_7E4AC40F9A5A28A58079BCC08626536D" xlink:to="loc_us-gaap_EquityComponentDomain_77E70C9826A7B25F7BBEBCC086279444" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_F56FB9A74E686731704EBCC08627042F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_77E70C9826A7B25F7BBEBCC086279444" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_F56FB9A74E686731704EBCC08627042F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember" xlink:label="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_562386D0A545E92D3F45BCC086275365" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_F56FB9A74E686731704EBCC08627042F" xlink:to="loc_us-gaap_AccumulatedGainLossNetCashFlowHedgeParentMember_562386D0A545E92D3F45BCC086275365" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccumulatedTranslationAdjustmentMember" xlink:label="loc_us-gaap_AccumulatedTranslationAdjustmentMember_013E9D3756E22DD3C7B3BCC08628FB2B" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_F56FB9A74E686731704EBCC08627042F" xlink:to="loc_us-gaap_AccumulatedTranslationAdjustmentMember_013E9D3756E22DD3C7B3BCC08628FB2B" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AOCIAttributableToParentNetOfTaxRollForward" xlink:label="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_2927364EC11D92618956BCC08628BF09" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_0CF5F13DFB4A0310C77EBCC086289FB4" xlink:to="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_2927364EC11D92618956BCC08628BF09" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_EFE8875C1D12B22BDB5CBCC086281809" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_2927364EC11D92618956BCC08628BF09" xlink:to="loc_us-gaap_StockholdersEquity_EFE8875C1D12B22BDB5CBCC086281809" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent" xlink:label="loc_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent_B5F7CF7426CE7044D8EFBCC086292A07" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_2927364EC11D92618956BCC08628BF09" xlink:to="loc_us-gaap_OciBeforeReclassificationsBeforeTaxAttributableToParent_B5F7CF7426CE7044D8EFBCC086292A07" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsTax_BDFF8AF90BDC4286FFB1BCC086296256" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_2927364EC11D92618956BCC08628BF09" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsTax_BDFF8AF90BDC4286FFB1BCC086296256" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OciBeforeReclassificationsNetOfTaxAttributableToParent" xlink:label="loc_us-gaap_OciBeforeReclassificationsNetOfTaxAttributableToParent_FAF81D6ED53919134AAFBCC08629F747" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_2927364EC11D92618956BCC08628BF09" xlink:to="loc_us-gaap_OciBeforeReclassificationsNetOfTaxAttributableToParent_FAF81D6ED53919134AAFBCC08629F747" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent" xlink:label="loc_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent_11738DD1A1A0D32985F4BCC08629B421" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_2927364EC11D92618956BCC08628BF09" xlink:to="loc_us-gaap_ReclassificationFromAociCurrentPeriodBeforeTaxAttributableToParent_11738DD1A1A0D32985F4BCC08629B421" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ReclassificationFromAociCurrentPeriodTax" xlink:label="loc_us-gaap_ReclassificationFromAociCurrentPeriodTax_A93F1929928FC8FF6E53BCC08629D6B3" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_2927364EC11D92618956BCC08628BF09" xlink:to="loc_us-gaap_ReclassificationFromAociCurrentPeriodTax_A93F1929928FC8FF6E53BCC08629D6B3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ReclassificationFromAociCurrentPeriodNetOfTaxAttributableToParent" xlink:label="loc_us-gaap_ReclassificationFromAociCurrentPeriodNetOfTaxAttributableToParent_210BFC4380988177B0ACBCC086297A43" xlink:type="locator" />
    <link:definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_2927364EC11D92618956BCC08628BF09" xlink:to="loc_us-gaap_ReclassificationFromAociCurrentPeriodNetOfTaxAttributableToParent_210BFC4380988177B0ACBCC086297A43" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_D9A66B14941D826E8242BCC0862AF10A" xlink:type="locator" />
    <link:definitionArc order="8" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AOCIAttributableToParentNetOfTaxRollForward_2927364EC11D92618956BCC08628BF09" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_D9A66B14941D826E8242BCC0862AF10A" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/StockholdersEquityStatementOfStockholdersEquityDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ClassOfStockLineItems" xlink:label="loc_us-gaap_ClassOfStockLineItems_07437277E6E5E6ACD965BCBDA14C9164" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfStockByClassTable" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_6C3EA5E34D0B3E0DC48CBCBDA14AED87" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ClassOfStockLineItems_07437277E6E5E6ACD965BCBDA14C9164" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_6C3EA5E34D0B3E0DC48CBCBDA14AED87" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_99E9EA7E1832B758400CBCBDA14A019F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_6C3EA5E34D0B3E0DC48CBCBDA14AED87" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_99E9EA7E1832B758400CBCBDA14A019F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_E50950B50047B2332D4CBCBDA14BEA2E_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_99E9EA7E1832B758400CBCBDA14A019F" xlink:to="loc_us-gaap_EquityComponentDomain_E50950B50047B2332D4CBCBDA14BEA2E_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_EquityComponentDomain" xlink:label="loc_us-gaap_EquityComponentDomain_E50950B50047B2332D4CBCBDA14BEA2E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_99E9EA7E1832B758400CBCBDA14A019F" xlink:to="loc_us-gaap_EquityComponentDomain_E50950B50047B2332D4CBCBDA14BEA2E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockMember" xlink:label="loc_us-gaap_CommonStockMember_DBE7219D630FCE530530BCBDA14B3E9F" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_E50950B50047B2332D4CBCBDA14BEA2E" xlink:to="loc_us-gaap_CommonStockMember_DBE7219D630FCE530530BCBDA14B3E9F" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AdditionalPaidInCapitalMember" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_8300774A76A246B8D178BCBDA14B9D9C" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_E50950B50047B2332D4CBCBDA14BEA2E" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_8300774A76A246B8D178BCBDA14B9D9C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_TreasuryStockMember" xlink:label="loc_us-gaap_TreasuryStockMember_F5A49776835BD71CD927BCBDA14B2095" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_E50950B50047B2332D4CBCBDA14BEA2E" xlink:to="loc_us-gaap_TreasuryStockMember_F5A49776835BD71CD927BCBDA14B2095" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_F84905C5C427F845DDABBCBDA14CFF8C" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_E50950B50047B2332D4CBCBDA14BEA2E" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_F84905C5C427F845DDABBCBDA14CFF8C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_RetainedEarningsMember" xlink:label="loc_us-gaap_RetainedEarningsMember_1668A393C55B16F8AC80BCBDA14C5B2A" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_E50950B50047B2332D4CBCBDA14BEA2E" xlink:to="loc_us-gaap_RetainedEarningsMember_1668A393C55B16F8AC80BCBDA14C5B2A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01BCC91EFD65E5751876BCBDA14CF675" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockLineItems_07437277E6E5E6ACD965BCBDA14C9164" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01BCC91EFD65E5751876BCBDA14CF675" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CommonStockSharesIssued" xlink:label="loc_us-gaap_CommonStockSharesIssued_4D810BEE1214675D9B34BCBDA14D7C96" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01BCC91EFD65E5751876BCBDA14CF675" xlink:to="loc_us-gaap_CommonStockSharesIssued_4D810BEE1214675D9B34BCBDA14D7C96" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_D2B2FAE36A8332FB15D9BCBDA14D4693" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01BCC91EFD65E5751876BCBDA14CF675" xlink:to="loc_us-gaap_StockholdersEquity_D2B2FAE36A8332FB15D9BCBDA14D4693" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CumulativeEffectOfNewAccountingPrincipleInPeriodOfAdoption" xlink:label="loc_us-gaap_CumulativeEffectOfNewAccountingPrincipleInPeriodOfAdoption_51EEBDA26E320E09182FBCBDA14D24DF" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01BCC91EFD65E5751876BCBDA14CF675" xlink:to="loc_us-gaap_CumulativeEffectOfNewAccountingPrincipleInPeriodOfAdoption_51EEBDA26E320E09182FBCBDA14D24DF" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation_7D7B743D9B4E1A5165C4BCBDA14D42E8" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01BCC91EFD65E5751876BCBDA14CF675" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesShareBasedCompensation_7D7B743D9B4E1A5165C4BCBDA14D42E8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation_822D8AABA0C01619FA60BCBDA14D9371" xlink:type="locator" />
    <link:definitionArc order="5" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01BCC91EFD65E5751876BCBDA14CF675" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation_822D8AABA0C01619FA60BCBDA14D9371" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_56D311735529725835E8BCBDA14E5AF5" xlink:type="locator" />
    <link:definitionArc order="6" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01BCC91EFD65E5751876BCBDA14CF675" xlink:to="loc_us-gaap_NetIncomeLoss_56D311735529725835E8BCBDA14E5AF5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_D2DA48A9D1293FDFDA2DBCBDA14E9693" xlink:type="locator" />
    <link:definitionArc order="7" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_01BCC91EFD65E5751876BCBDA14CF675" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_D2DA48A9D1293FDFDA2DBCBDA14E9693" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/StockholdersEquityTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformation" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationSummaryOfAccruedLiabilitiesDetails" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationSummaryOfInventoryDetails" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/SupplementalFinancialInformationTables" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/UnauditedCondensedConsolidatedFinancialStatements" xlink:type="extended" />
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/UnauditedCondensedConsolidatedFinancialStatementsNarrativeDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_9B682F180830F69042A8BE84BD6825F4" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_FEBA2226F682C93AD7FABE84BD66799B" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_9B682F180830F69042A8BE84BD6825F4" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_FEBA2226F682C93AD7FABE84BD66799B" xlink:type="arc" xbrldt:closed="true" xbrldt:contextElement="segment" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_8BD36A0DB254B29CEC57BEAFF64B8568" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_FEBA2226F682C93AD7FABE84BD66799B" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_8BD36A0DB254B29CEC57BEAFF64B8568" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_70021A43CF2751BFC333BEAFF64EAD5A_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_8BD36A0DB254B29CEC57BEAFF64B8568" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_70021A43CF2751BFC333BEAFF64EAD5A_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_70021A43CF2751BFC333BEAFF64EAD5A" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_8BD36A0DB254B29CEC57BEAFF64B8568" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_70021A43CF2751BFC333BEAFF64EAD5A" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_InProcessResearchAndDevelopmentMember" xlink:label="loc_us-gaap_InProcessResearchAndDevelopmentMember_7FCB625FEEF023270A07BEB07203929E" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_70021A43CF2751BFC333BEAFF64EAD5A" xlink:to="loc_us-gaap_InProcessResearchAndDevelopmentMember_7FCB625FEEF023270A07BEB07203929E" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_3C7E3F86E6A4AE649840BE84BD672201" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_FEBA2226F682C93AD7FABE84BD66799B" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_3C7E3F86E6A4AE649840BE84BD672201" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_FB3778486BD7DD52A371BE84BD679ADA_default" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_3C7E3F86E6A4AE649840BE84BD672201" xlink:to="loc_us-gaap_SegmentDomain_FB3778486BD7DD52A371BE84BD679ADA_default" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SegmentDomain" xlink:label="loc_us-gaap_SegmentDomain_FB3778486BD7DD52A371BE84BD679ADA" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_3C7E3F86E6A4AE649840BE84BD672201" xlink:to="loc_us-gaap_SegmentDomain_FB3778486BD7DD52A371BE84BD679ADA" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_CardiovascularSegmentMember" xlink:label="loc_livn_CardiovascularSegmentMember_B418414F77D50D607BD2BE84BD67FC15" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_FB3778486BD7DD52A371BE84BD679ADA" xlink:to="loc_livn_CardiovascularSegmentMember_B418414F77D50D607BD2BE84BD67FC15" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_NeuromodulationSegmentMember" xlink:label="loc_livn_NeuromodulationSegmentMember_CD50E8C6A7112C272FC4BE84BD670FC9" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_FB3778486BD7DD52A371BE84BD679ADA" xlink:to="loc_livn_NeuromodulationSegmentMember_CD50E8C6A7112C272FC4BE84BD670FC9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_241B97F6DBF69F0C3D32BE84BD6888A8" xlink:type="locator" />
    <link:definitionArc order="1" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_9B682F180830F69042A8BE84BD6825F4" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_241B97F6DBF69F0C3D32BE84BD6888A8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_CC85CC7591EBD60968C4BE84BD688CCF" xlink:type="locator" />
    <link:definitionArc order="2" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_9B682F180830F69042A8BE84BD6825F4" xlink:to="loc_us-gaap_Goodwill_CC85CC7591EBD60968C4BE84BD688CCF" xlink:type="arc" />
    <link:loc xlink:href="livn-20200331.xsd#livn_GoodwillImpairmentTestHeadRoomPercentage" xlink:label="loc_livn_GoodwillImpairmentTestHeadRoomPercentage_1A932C1C2BDF3492E66FBE84BD68181C" xlink:type="locator" />
    <link:definitionArc order="3" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_9B682F180830F69042A8BE84BD6825F4" xlink:to="loc_livn_GoodwillImpairmentTestHeadRoomPercentage_1A932C1C2BDF3492E66FBE84BD68181C" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_52735D0EA65FDCEB8647BEAFCC15FF3C" xlink:type="locator" />
    <link:definitionArc order="4" xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_9B682F180830F69042A8BE84BD6825F4" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_52735D0EA65FDCEB8647BEAFCC15FF3C" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.livanova.cyberonics.com/role/UnauditedCondensedConsolidatedFinancialStatementsPolicies" xlink:type="extended" />
</link:linkbase>
